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The fused lasso, also known as total-variation denoising, is a locally-adaptive function estimator over a regular grid of design points. In this paper, we extend the fused lasso to settings in which the points do not occur on a regular…

Methodology · Statistics 2019-07-09 Oscar Hernan Madrid Padilla , James Sharpnack , Yanzhen Chen , Daniela M. Witten

We consider the problem of estimating a sparse multi-response regression function, with an application to expression quantitative trait locus (eQTL) mapping, where the goal is to discover genetic variations that influence gene-expression…

Machine Learning · Statistics 2012-10-01 Seyoung Kim , Eric P. Xing

This article introduces the sparse group fused lasso (SGFL) as a statistical framework for segmenting sparse regression models with multivariate time series. To compute solutions of the SGFL, a nonsmooth and nonseparable convex program, we…

Computation · Statistics 2020-10-09 David Degras

Many complex disease syndromes such as asthma consist of a large number of highly related, rather than independent, clinical phenotypes, raising a new technical challenge in identifying genetic variations associated simultaneously with…

Machine Learning · Statistics 2008-11-16 Seyoung Kim , Kyung-Ah Sohn , Eric P. Xing

Graph-regularized semi-supervised learning has been used effectively for classification when (i) instances are connected through a graph, and (ii) labeled data is scarce. If available, using multiple relations (or graphs) between the…

Machine Learning · Computer Science 2015-10-22 Junting Ye , Leman Akoglu

Graph similarity learning, crucial for tasks such as graph classification and similarity search, focuses on measuring the similarity between two graph-structured entities. The core challenge in this field is effectively managing the…

Information Retrieval · Computer Science 2025-02-26 Zenghui Chang , Yiqiao Zhang , Hong Cai Chen

Latent structure methods, specifically linear continuous latent structure methods, are a type of fundamental statistical learning strategy. They are widely used for dimension reduction, regression and prediction, in the fields of…

Methodology · Statistics 2025-08-07 Clara Grazian , Qian Jin , Pierre Lafaye De Micheaux

We consider the task of estimating a Gaussian graphical model in the high-dimensional setting. The graphical lasso, which involves maximizing the Gaussian log likelihood subject to an l1 penalty, is a well-studied approach for this task. We…

Machine Learning · Statistics 2013-07-23 Kean Ming Tan , Daniela Witten , Ali Shojaie

The fused lasso penalizes a loss function by the $L_1$ norm for both the regression coefficients and their successive differences to encourage sparsity of both. In this paper, we propose a Bayesian generalized fused lasso modeling based on…

Methodology · Statistics 2019-07-15 Kaito Shimamura , Masao Ueki , Shuichi Kawano , Sadanori Konishi

We consider the problem of estimating multiple related but distinct graphical models on the basis of a high-dimensional data set with observations that belong to distinct classes. A motivating example occurs in the analysis of gene…

Methodology · Statistics 2012-07-12 Patrick Danaher , Pei Wang , Daniela M. Witten

Large-scale {\it in vitro} drug sensitivity screens are an important tool in personalized oncology to predict the effectiveness of potential cancer drugs. The prediction of the sensitivity of cancer cell lines to a panel of drugs is a…

Methodology · Statistics 2020-03-10 Zhi Zhao , Manuela Zucknick

Fuzzy systems (FSs) have enjoyed wide applications in various fields, including pattern recognition, intelligent control, data mining and bioinformatics, which is attributed to the strong interpretation and learning ability. In traditional…

Artificial Intelligence · Computer Science 2023-09-21 Fuping Hu , Zhaohong Deng , Zhenping Xie , Kup-Sze Choi , Shitong Wang

In this paper, we propose an adaptive group Lasso deep neural network for high-dimensional function approximation where input data are generated from a dynamical system and the target function depends on few active variables or few linear…

Machine Learning · Computer Science 2021-12-06 Lam Si Tung Ho , Nicholas Richardson , Giang Tran

This thesis studies two problems in modern statistics. First, we study selective inference, or inference for hypothesis that are chosen after looking at the data. The motiving application is inference for regression coefficients selected by…

Machine Learning · Statistics 2015-07-02 Jason D. Lee

The regression of multiple inter-connected sequence data is a problem in various disciplines. Formally, we name the regression problem of multiple inter-connected data entities as the "dynamic network regression" in this paper. Within the…

Machine Learning · Computer Science 2020-10-19 Yixin Chen , Lin Meng , Jiawei Zhang

Previous research has sought to enhance the graph reasoning capabilities of LLMs by supervised fine-tuning on synthetic graph data. While these led to specialized LLMs better at solving graph algorithm problems, we don't need LLMs for…

Machine Learning · Computer Science 2025-08-19 Yizhuo Zhang , Heng Wang , Shangbin Feng , Zhaoxuan Tan , Xinyun Liu , Yulia Tsvetkov

Gaussian graphical models are recently used in economics to obtain networks of dependence among agents. A widely-used estimator is the Graphical Lasso (GLASSO), which amounts to a maximum likelihood estimation regularized using the…

Econometrics · Economics 2017-10-03 Khai X. Chiong , Hyungsik Roger Moon

Graphical Lasso (GL) is a popular method for learning the structure of an undirected graphical model, which is based on an $l_1$ regularization technique. The objective of this paper is to compare the computationally-heavy GL technique with…

Machine Learning · Statistics 2019-07-02 Salar Fattahi , Somayeh Sojoudi

We propose a multinomial logistic regression model for link prediction in a time series of directed binary networks. To account for the dynamic nature of the data we employ a dynamic model for the model parameters that is strongly connected…

Applications · Statistics 2017-10-05 Brenda Betancourt , Abel Rodríguez , Naomi Boyd

Relational databases are extensively utilized in a variety of modern information system applications, and they always carry valuable data patterns. There are a huge number of data mining or machine learning tasks conducted on relational…

Machine Learning · Computer Science 2023-12-05 Han Zhang , Quan Gan , David Wipf , Weinan Zhang