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The aim of this chapter is to convey the importance and usefulness of mathematical modelling as a tool to achieve a deeper understanding of stem cell biology. We introduce key mathematical concepts (random walk theory, differential…

Cell Behavior · Quantitative Biology 2020-10-30 Laura E Wadkin , Sirio Orozco-Fuentes , Irina Neganova , Majlinda Lako , Nicholas G Parker , Anvar Shukurov

Graphs are central to the chemical sciences, providing a natural language to describe molecules, proteins, reactions, and industrial processes. They capture interactions and structures that underpin materials, biology, and medicine. This…

This paper investigates Gaussian Markov random field approximations to nonstationary Gaussian fields using graph representations of stochastic partial differential equations. We establish approximation error guarantees building on the…

Methodology · Statistics 2021-04-28 Daniel Sanz-Alonso , Ruiyi Yang

Graphs and networks provide a canonical representation of relational data, with massive network data sets becoming increasingly prevalent across a variety of scientific fields. Although tools from mathematics and computer science have been…

Methodology · Statistics 2014-08-11 Benjamin P. Olding , Patrick J. Wolfe

In this article, the notion of a mathematical model in science is attempted to be enlightened from several points of view. In particular, it is shown that mathematical models are introduced differently and used differently in different…

History and Overview · Mathematics 2022-05-25 Inge S. Helland

We introduce a rigorous framework for stochastic cell transmission models for general traffic networks. The performance of traffic systems is evaluated based on preference functionals and acceptable designs. The numerical implementation…

Machine Learning · Computer Science 2023-04-25 Zachary Feinstein , Marcel Kleiber , Stefan Weber

Foundation models have emerged as critical components in a variety of artificial intelligence applications, and showcase significant success in natural language processing and several other domains. Meanwhile, the field of graph machine…

Machine Learning · Computer Science 2025-03-11 Jiawei Liu , Cheng Yang , Zhiyuan Lu , Junze Chen , Yibo Li , Mengmei Zhang , Ting Bai , Yuan Fang , Lichao Sun , Philip S. Yu , Chuan Shi

We explore the use of graph neural networks (GNNs) to model spatial processes in which there is no a priori graphical structure. Similar to finite element analysis, we assign nodes of a GNN to spatial locations and use a computational…

Machine Learning · Computer Science 2019-11-19 Ferran Alet , Adarsh K. Jeewajee , Maria Bauza , Alberto Rodriguez , Tomas Lozano-Perez , Leslie Pack Kaelbling

We introduce efficient Markov chain Monte Carlo methods for inference and model determination in multivariate and matrix-variate Gaussian graphical models. Our framework is based on the G-Wishart prior for the precision matrix associated…

Methodology · Statistics 2010-05-25 Adrian Dobra , Alex Lenkoski , Abel Rodriguez

A goal of systems biology is to understand the dynamics of intracellular systems. Stochastic chemical kinetic models are often utilized to accurately capture the stochastic nature of these systems due to low numbers of molecules. Collecting…

Computation · Statistics 2015-03-17 Jarad Niemi , Matthew Wheeler

This work in progress aims to provide a unified introduction to statistical learning, building up slowly from classical models like the GMM and HMM to modern neural networks like the VAE and diffusion models. There are today many internet…

Machine Learning · Computer Science 2025-07-31 Joseph G. Makin

Graphs arise naturally in many real-world applications including social networks, recommender systems, ontologies, biology, and computational finance. Traditionally, machine learning models for graphs have been mostly designed for static…

Machine Learning · Computer Science 2020-04-28 Seyed Mehran Kazemi , Rishab Goel , Kshitij Jain , Ivan Kobyzev , Akshay Sethi , Peter Forsyth , Pascal Poupart

Graphs are commonly used to characterise interactions between objects of interest. Because they are based on a straightforward formalism, they are used in many scientific fields from computer science to historical sciences. In this paper,…

Machine Learning · Statistics 2015-06-24 Pierre Latouche , Fabrice Rossi

Recent developments in Machine Learning approaches for modelling physical systems have begun to mirror the past development of numerical methods in the computational sciences. In this survey, we begin by providing an example of this with…

Machine Learning · Computer Science 2023-04-04 Artur P. Toshev , Ludger Paehler , Andrea Panizza , Nikolaus A. Adams

This paper explores the versatility and depth of Bayesian modeling by presenting a comprehensive range of applications and methods, combining Markov chain Monte Carlo (MCMC) techniques and variational approximations. Covering topics such as…

Applications · Statistics 2025-02-18 Yifei Yan , Juan Sosa , Carlos A. Martínez

Graph neural networks have emerged as a leading architecture for many graph-level tasks, such as graph classification and graph generation. As an essential component of the architecture, graph pooling is indispensable for obtaining a…

Machine Learning · Computer Science 2023-06-23 Chuang Liu , Yibing Zhan , Jia Wu , Chang Li , Bo Du , Wenbin Hu , Tongliang Liu , Dacheng Tao

In this paper, we propose a simple, versatile model for learning the structure and parameters of multivariate distributions from a data set. Learning a Markov network from a given data set is not a simple problem, because Markov networks…

Machine Learning · Computer Science 2012-06-19 Kazuya Takabatake , Shotaro Akaho

Diffusion models, as a novel generative paradigm, have achieved remarkable success in various image generation tasks such as image inpainting, image-to-text translation, and video generation. Graph generation is a crucial computational task…

Machine Learning · Computer Science 2023-08-29 Chengyi Liu , Wenqi Fan , Yunqing Liu , Jiatong Li , Hang Li , Hui Liu , Jiliang Tang , Qing Li

We explore a simple mathematical model of network computation, based on Markov chains. Similar models apply to a broad range of computational phenomena, arising in networks of computers, as well as in genetic, and neural nets, in social…

Information Retrieval · Computer Science 2009-04-18 Dusko Pavlovic

In this paper, we outline a model of graph (or network) dynamics based on two ingredients. The first ingredient is a Markov chain on the space of possible graphs. The second ingredient is a semi-Markov counting process of renewal type. The…

Probability · Mathematics 2015-05-28 Marco Raberto , Fabio Rapallo , Enrico Scalas