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Although the immune response is often regarded as acting to suppress tumor growth, it is now clear that it can be both stimulatory and inhibitory. The interplay between these competing influences has complex implications for tumor…

Cell Behavior · Quantitative Biology 2013-05-17 Kathleen P. Wilkie , Philip Hahnfeldt

Risk-driven behavior provides a feedback mechanism through which individuals both shape and are collectively affected by an epidemic. We introduce a general and flexible compartmental model to study the effect of heterogeneity in the…

We present a method based on a time domain simulation of wave propagation that allows studying the optical response of a broad range of dielectric photonic structures. This method is particularly suitable for dealing with complex biological…

Computational Physics · Physics 2013-01-07 Andrés E. Dolinko , Diana C. Skigin

A model of an organism as an autonomous intelligent system has been proposed. This model was used to analyze learning of an organism in various environmental conditions. Processes of learning were divided into two types: strong and weak…

Artificial Intelligence · Computer Science 2007-05-23 Alexey V. Melkikh

We develop a theory for the susceptible-infected-susceptible (SIS) epidemic model on networks that incorporate both network structure and dynamic correlations. This theory can account for the multistage onset of the epidemic phase in…

Physics and Society · Physics 2021-04-07 Chao-Ran Cai , Zhi-Xi Wu , Petter Holme

A deterministic cellular automaton rule defined on the Moore neighbourhood is studied as a model of epidemic propagation. The directed nature of the interaction between cells allows one to introduce the dependence on a disorder parameter…

Statistical Mechanics · Physics 2007-05-23 M. Bezzi , R. Livi

Biological systems, unlike physical or chemical systems, are characterized by the very inhomogeneous distribution of their components. The immune system, in particular, is notable for self-organizing its structure. Classically, the dynamics…

Statistical Mechanics · Physics 2007-05-23 Yoram Louzoun , Sorin Solomon , Henri Atlan , Irun R. Cohen

The spread of certain diseases can be promoted, in some cases substantially, by prior infection with another disease. One example is that of HIV, whose immunosuppressant effects significantly increase the chances of infection with other…

Physics and Society · Physics 2014-08-04 M. E. J. Newman , C. R. Ferrario

Infectious diseases are practically represented by models with multiple states and complex transition rules corresponding to, for example, birth, death, infection, recovery, disease progression, and quarantine. In addition, networks…

Disordered Systems and Neural Networks · Physics 2007-05-23 Naoki Masuda , Norio Konno

Many pathogens spread primarily via direct contact between infected and susceptible hosts. Thus, the patterns of contacts or contact network of a population fundamentally shapes the course of epidemics. While there is a robust and growing…

Populations and Evolution · Quantitative Biology 2012-08-01 Shweta Bansal , Lauren Ancel Meyers

The stacked contact process is a stochastic model for the spread of an infection within a population of hosts located on the $d$-dimensional integer lattice. Regardless of whether they are healthy or infected, hosts give birth and die at…

Probability · Mathematics 2014-10-16 Nicolas Lanchier , Yuan Zhang

Biological systems, from cells to organisms, must respond to the ever changing environment in order to survive and function. This is not a simple task given the often random nature of the signals they receive, as well as the intrinsically…

Quantitative Methods · Quantitative Biology 2015-07-09 Aleksandra M. Walczak

Infectious diseases outbreaks are often characterized by a spatial component induced by hosts' distribution, mobility, and interactions. Spatial models that incorporate hosts' movements are being used to describe these processes, to…

Physics and Society · Physics 2012-07-20 Chiara Poletto , Michele Tizzoni , Vittoria Colizza

In this paper, we give a complete analysis of an SIS epidemiological model in a population of varying size with two dissimilar groups of infective individuals. It is mainly based on the discussion of the existence and stability of…

Classical Analysis and ODEs · Mathematics 2007-05-23 M. R. Razvan

This paper is a survey paper on stochastic epidemic models. A simple stochastic epidemic model is defined and exact and asymptotic model properties (relying on a large community) are presented. The purpose of modelling is illustrated by…

Probability · Mathematics 2009-11-05 Tom Britton

Epidemiological models for the spread of pathogens in a population are usually only able to describe a single pathogen. This makes their application unrealistic in cases where multiple pathogens with similar symptoms are spreading…

Social and Information Networks · Computer Science 2018-05-16 Nir Levy , Michael Iv , Elad Yom-Tov

Epidemiological models describe the spread of an infectious disease within a population. They capture microscopic details on how the disease is passed on among individuals in various different ways, while making predictions about the state…

Populations and Evolution · Quantitative Biology 2024-02-27 Stefan Hohenegger , Francesco Sannino

As the development of a dengue vaccine is ongoing, we simulate an hypothetical vaccine as an extra protection to the population. In a first phase, the vaccination process is studied as a new compartment in the model, and different ways of…

Optimization and Control · Mathematics 2013-11-26 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres

We analyze infection spreading processes in a system where only a fraction $p$ of individuals can be affected by disease, while remaining $1-p$ individuals are immune. Such a picture can emerge as a natural consequence of previously…

Disordered Systems and Neural Networks · Physics 2021-12-06 V. Blavatska , Yu. Holovatch

We consider a reaction-diffusion system including discontinuous hysteretic relay operators in reaction terms. This system is motivated by an epigenetic model that describes the evolution of a population of organisms which can switch their…

Analysis of PDEs · Mathematics 2015-08-12 Pavel Gurevich , Dmitrii Rachinskii