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Patchwork learning arises as a new and challenging data collection paradigm where both samples and features are observed in fragmented subsets. Due to technological limits, measurement expense, or multimodal data integration, such patchwork…

Methodology · Statistics 2024-06-21 Lili Zheng , Andersen Chang , Genevera I. Allen

The advent of next-generation sequencing-based spatially resolved transcriptomics (SRT) techniques has reshaped genomic studies by enabling high-throughput gene expression profiling while preserving spatial and morphological context.…

Applications · Statistics 2025-02-20 Bencong Zhu , Alberto Cassese , Marina Vannucci , Michele Guindani , Qiwei Li

In this paper, we consider feature screening for ultrahigh dimensional clustering analyses. Based on the observation that the marginal distribution of any given feature is a mixture of its conditional distributions in different clusters, we…

Methodology · Statistics 2024-02-05 Changhu Wang , Zihao Chen , Ruibin Xi

Data clustering is a process of arranging similar data into groups. A clustering algorithm partitions a data set into several groups such that the similarity within a group is better than among groups. In this paper a hybrid clustering…

Databases · Computer Science 2012-05-25 Ravindra Jain

We present a structural clustering algorithm for large-scale datasets of small labeled graphs, utilizing a frequent subgraph sampling strategy. A set of representatives provides an intuitive description of each cluster, supports the…

Databases · Computer Science 2016-10-03 Till Schäfer , Petra Mutzel

With the explosive growth of multi-source data, multi-view clustering has attracted great attention in recent years. Most existing multi-view methods operate in raw feature space and heavily depend on the quality of original feature…

Machine Learning · Computer Science 2022-05-20 Liang Liu , Peng Chen , Guangchun Luo , Zhao Kang , Yonggang Luo , Sanchu Han

Important tasks in the study of genomic data include the identification of groups of similar cells (for example by clustering), and visualisation of data summaries (for example by dimensional reduction). In this paper, we develop a novel…

Methodology · Statistics 2024-10-15 Thomas E. Bartlett , Swati Chandna , Sandipan Roy

In this work we seek clusters of genomic words in human DNA by studying their inter-word lag distributions. Due to the particularly spiked nature of these histograms, a clustering procedure is proposed that first decomposes each…

Applications · Statistics 2021-01-13 Ana Helena Tavares , Jakob Raymaekers , Peter J. Rousseeuw , Paula Brito , Vera Afreixo

Temporal data, obtained in the setting where it is only possible to observe one time point per experiment, is widely used in different research fields, yet remains insufficiently addressed from the statistical point of view. Such data often…

Methodology · Statistics 2025-03-10 Polina Arsenteva , Mohamed Amine Benadjaoud , Hervé Cardot

To understand complex biological systems, the research community has produced huge corpus of gene expression data. A large number of clustering approaches have been proposed for the analysis of gene expression data. However, extracting…

Computational Engineering, Finance, and Science · Computer Science 2010-03-28 Swathi. H

We consider the problem of clustering data points in high dimensions, i.e. when the number of data points may be much smaller than the number of dimensions. Specifically, we consider a Gaussian mixture model (GMM) with non-spherical…

Statistics Theory · Mathematics 2014-06-10 Martin Azizyan , Aarti Singh , Larry Wasserman

Spatial transcriptomics is a modern sequencing technology that allows the measurement of the activity of thousands of genes in a tissue sample and map where the activity is occurring. This technology has enabled the study of the so-called…

Methodology · Statistics 2022-09-15 Andrea Sottosanti , Davide Risso

We consider a discrete latent variable model for two-way data arrays, which allows one to simultaneously produce clusters along one of the data dimensions (e.g. exchangeable observational units or features) and contiguous groups, or…

We study the clustering problem for mixtures of bounded covariance distributions, under a fine-grained separation assumption. Specifically, given samples from a $k$-component mixture distribution $D = \sum_{i =1}^k w_i P_i$, where each $w_i…

Machine Learning · Computer Science 2023-12-20 Ilias Diakonikolas , Daniel M. Kane , Jasper C. H. Lee , Thanasis Pittas

The method of Hol\'y, Sokol and \v{C}ern\'y (Applied Soft Computing, 2017, Vol. 60, p. 752-762) clusters objects based on their incidence in a large number of given sets. The idea is to minimize the occurrence of multiple objects from the…

Artificial Intelligence · Computer Science 2021-02-03 Ondřej Sokol , Vladimír Holý

Large datasets with interactions between objects are common to numerous scientific fields (i.e. social science, internet, biology...). The interactions naturally define a graph and a common way to explore or summarize such dataset is graph…

Applications · Statistics 2009-10-13 Hugo Zanghi , Stevenn Volant , Christophe Ambroise

Due to the wider availability of modern electronic health records, patient care data is often being stored in the form of time-series. Clustering such time-series data is crucial for patient phenotyping, anticipating patients' prognoses by…

Medical Physics · Physics 2020-06-17 Changhee Lee , Mihaela van der Schaar

Spectral clustering algorithms typically require a priori selection of input parameters such as the number of clusters, a scaling parameter for the affinity measure, or ranges of these values for parameter tuning. Despite efforts for…

Machine Learning · Computer Science 2019-03-20 Milad Afzalan , Farrokh Jazizadeh

Motivation. Understanding the pan-cancer mutational landscape offers critical insights into the molecular mechanisms underlying tumorigenesis. While patient-level machine learning techniques have been widely employed to identify tumor…

Machine Learning · Computer Science 2025-08-29 Yifan Dou , Adam Khadre , Ruben C Petreaca , Golrokh Mirzaei

Spatial clustering is a crucial field, finding universal use across criminology, pathology, and urban planning. However, most spatial clustering algorithms cannot pull information from nearby nodes and suffer performance drops when dealing…

Machine Learning · Computer Science 2025-03-12 Aidan Gao , Junhong Lin