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In oncology, phase II studies are crucial for clinical development plans as such studies identify potent agents with sufficient activity to continue development in the subsequent phase III trials. Traditionally, phase II studies are…

Methodology · Statistics 2023-08-08 Takuya Yoshimoto , Satoru Shinoda , Kouji Yamamoto , Kouji Tahata

In this article we consider two-grid finite element methods for solving semilinear interface problems in d space dimensions, for d=2 or d=3. We first describe in some detail the target problem class with discontinuous diffusion…

Numerical Analysis · Mathematics 2012-03-05 Michael Holst , Ryan Szypowski , Yunrong Zhu

The point inclusion tests for polygons, in other words the point-in-polygon (PIP) algorithms, are fundamental tools for many scientific fields related to computational geometry, and they have been studied for a long time. The PIP algorithms…

Computational Geometry · Computer Science 2021-02-03 Rahman Salim Zengin , Volkan Sezer

We propose a roadmap for bootstrapping conformal field theories (CFTs) described by gauge theories in dimensions $d>2$. In particular, we provide a simple and workable answer to the question of how to detect the gauge group in the bootstrap…

High Energy Physics - Theory · Physics 2021-12-29 Yin-Chen He , Junchen Rong , Ning Su

In this paper, I have proved that for a class of polynomial differential systems of degree n+1 ( where n is an arbitrary positive integer) the composition conjecture is true. I give the sufficient and necessary conditions for these…

Classical Analysis and ODEs · Mathematics 2019-05-01 Zhengxin Zhou

Evolution in its course found a variety of solutions to the same optimisation problem. The advent of high-throughput genomic sequencing has made available extensive data from which, in principle, one can infer the underlying structure on…

Quantitative Methods · Quantitative Biology 2016-04-12 Silvia Grigolon , Silvio Franz , Matteo Marsili

Earlier the authors considered and, in some cases, computed Poincare series of two sorts of multi-index filtrations on the ring of germs of functions on a complex (normal) surface singularity (in particular on the complex plane). A…

Algebraic Geometry · Mathematics 2008-09-12 A. Campillo , F. Delgado , S. M. Gusein-Zade

This work studies the problem of panoptic symbol spotting, which is to spot and parse both countable object instances (windows, doors, tables, etc.) and uncountable stuff (wall, railing, etc.) from computer-aided design (CAD) drawings.…

Computer Vision and Pattern Recognition · Computer Science 2024-01-22 Wenlong Liu , Tianyu Yang , Yuhan Wang , Qizhi Yu , Lei Zhang

We consider the population of critical points, generated from the critical point of the master function with no variables, which is associated with the trivial representation of the twisted affine Lie algebra $C_n^{(1)}$. The population is…

Algebraic Geometry · Mathematics 2018-11-09 Alexander Varchenko , Tyler Woodruff

We study a class of one-dimensional full branch maps admitting two indifferent fixed points as well as critical points and/or unbounded derivative. Under some mild assumptions we prove the existence of a unique invariant mixing absolutely…

Dynamical Systems · Mathematics 2024-05-28 Douglas Coates , Stefano Luzzatto , Muhammad Mubarak

We study four-point functions of critical percolation in two dimensions, and more generally of the Potts model. We propose an exact ansatz for the spectrum: an infinite, discrete and non-diagonal combination of representations of the…

High Energy Physics - Theory · Physics 2018-04-20 Marco Picco , Sylvain Ribault , Raoul Santachiara

Identification of local structure in intensive data -- such as time series, images, and higher dimensional processes -- is an important problem in astronomy. Since the data are typically generated by an inhomogeneous Poisson process, an…

Data Analysis, Statistics and Probability · Physics 2007-05-23 Jeffrey D. Scargle

Computing mountain passes is a standard way of finding critical points. We describe a numerical method for finding critical points that is convergent in the nonsmooth case and locally superlinearly convergent in the smooth finite…

Numerical Analysis · Mathematics 2011-06-14 Adrian S. Lewis , C. H. Jeffrey Pang

Scanning probes reveal complex, inhomogeneous patterns on the surface of many condensed matter systems. In some cases, the patterns form self-similar, fractal geometric clusters. In this paper, we advance the theory of criticality as it…

Strongly Correlated Electrons · Physics 2021-11-11 Shuo Liu , E. W. Carlson , K. A. Dahmen

We use dual graphs and generating sequences of valuations to compute the Poincare series of non-divisorial valuations on function fields of dimension two. The Poincare series are shown to reflect data from the dual graphs and hence carry…

Commutative Algebra · Mathematics 2026-03-31 Charles Li , Hans Schoutens

The classic Voronoi cells can be generalized to a higher-order version by considering the cells of points for which a given $k$-element subset of the set of sites consists of the $k$ closest sites. We study the structure of the $k$-order…

Metric Geometry · Mathematics 2019-06-14 Juan Enrique Martínez-Legaz , Vera Roshchina , Maxim Todorov

The fixed point that governs the critical behavior of magnets described by the $N$-vector chiral model under the physical values of $N$ ($N =2, 3$) is shown to be a stable focus both in two and three dimensions. Robust evidence in favor of…

Statistical Mechanics · Physics 2009-11-07 P. Calabrese , P. Parruccini , A. I. Sokolov

Given any n-tuple of complex numbers, one can canonically define a polynomial of degree n+1 that has the entries of this n-tuple as its critical points. In 2002, Beardon, Carne, and Ng studied a map $\theta\colon \mathbb{C}^n\to…

Complex Variables · Mathematics 2019-08-29 Michael Dougherty , Jon McCammond

The presence of slow-fast Hopf (or singular Hopf) points in slow-fast systems in the plane is often deduced from the shape of a vector field brought into normal form. It can however be quite cumbersome to put a system in normal form. In the…

Dynamical Systems · Mathematics 2021-11-10 Peter De Maesschalck , Thai Son Doan , Jeroen Wynen

We proposed a new universal method for significantly increasing accuracy of critical points of 2 and 3-dimensional Ising models and exploring fluctuation mechanism. The method is based on analysis of block fractals and the renormalization…

General Physics · Physics 2010-07-12 You-gang Feng