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Biological neurons can detect complex spatio-temporal features in spiking patterns via their synapses spread across across their dendritic branches. This is achieved by modulating the efficacy of the individual synapses, and by exploiting…

Emerging Technologies · Computer Science 2023-12-15 Melika Payvand , Simone D'Agostino , Filippo Moro , Yigit Demirag , Giacomo Indiveri , Elisa Vianello

Performing anomaly detection in hybrid systems is a challenging task since it requires analysis of timing behavior and mutual dependencies of both discrete and continuous signals. Typically, it requires modeling system behavior, which is…

Machine Learning · Computer Science 2020-10-30 Nemanja Hranisavljevic , Oliver Niggemann , Alexander Maier

Migration of cells can be characterized by two, prototypical types of motion: individual and collective migration. We propose a statistical-inference approach designed to detect the presence of cell-cell interactions that give rise to…

Cell Behavior · Quantitative Biology 2020-03-13 Elena Agliari , Pablo J. Sáez , Adriano Barra , Matthieu Piel , Pablo Vargas , Michele Castellana

Quality inspection applications in industry are required to move towards a zero-defect manufacturing scenario, withnon-destructive inspection and traceability of 100 % of produced parts. Developing robust fault detection and classification…

Computer Vision and Pattern Recognition · Computer Science 2021-07-08 Julen Balzategui , Luka Eciolaza , Daniel Maestro-Watson

The problem of \emph{statistical recognition} is considered, as it arises in immunobiology, namely, the discrimination of foreign antigens against a background of the body's own molecules. The precise mechanism of this…

Subcellular Processes · Quantitative Biology 2009-09-30 Florian Lipsmeier , Ellen Baake

The process of identifying and characterizing B-cell epitopes, which are the portions of antigens recognized by antibodies, is important for our understanding of the immune system, and for many applications including vaccine development,…

Quantitative Methods · Quantitative Biology 2025-12-10 Xiao Yuan

For over a century, immunology has masterfully discovered and dissected the components of our immune system, yet its collective behavior remains fundamentally unpredictable. In this perspective, we argue that building on the learnings of…

Anomaly detection consists in identifying, within a dataset, those samples that significantly differ from the majority of the data, representing the normal class. It has many practical applications, e.g. ranging from defective product…

Computer Vision and Pattern Recognition · Computer Science 2020-11-13 Pankaj Mishra , Claudio Piciarelli , Gian Luca Foresti

It has been known for some time that human autoimmune diseases can be triggered by viral infections. Several possible mechanisms of interactions between a virus and immune system have been analysed, with a prevailing opinion being that the…

Populations and Evolution · Quantitative Biology 2012-09-21 K. B. Blyuss , L. B. Nicholson

Anomaly detection aims to detect abnormal events by a model of normality. It plays an important role in many domains such as network intrusion detection, criminal activity identity and so on. With the rapidly growing size of accessible…

Machine Learning · Computer Science 2018-08-02 Chu Wang , Yan-Ming Zhang , Cheng-Lin Liu

Most of the existing methods for anomaly detection use only positive data to learn the data distribution, thus they usually need a pre-defined threshold at the detection stage to determine whether a test instance is an outlier.…

Machine Learning · Computer Science 2019-03-19 Kai Tian , Shuigeng Zhou , Jianping Fan , Jihong Guan

Biological organisms have evolved a wide range of immune mechanisms to defend themselves against pathogens. Beyond molecular details, these mechanisms differ in how protection is acquired, processed and passed on to subsequent generations…

Populations and Evolution · Quantitative Biology 2016-12-26 Andreas Mayer , Thierry Mora , Olivier Rivoire , Aleksandra M. Walczak

Automatic anomaly detection is a major issue in various areas. Beyond mere detection, the identification of the source of the problem that produced the anomaly is also essential. This is particularly the case in aircraft engine health…

Machine Learning · Statistics 2016-08-10 Tsirizo Rabenoro , Jérôme Lacaille , Marie Cottrell , Fabrice Rossi

Anomaly detection is critical for the secure and reliable operation of industrial control systems. As our reliance on such complex cyber-physical systems grows, it becomes paramount to have automated methods for detecting anomalies,…

Machine Learning · Computer Science 2024-05-10 Mayra Macas , Chunming Wu , Walter Fuertes

This work illustrates potentials for recognition within {\em ad hoc} sensor networks if their nodes possess individual inter-related biologically inspired genetic codes. The work takes ideas from natural immune systems protecting organisms…

Cryptography and Security · Computer Science 2009-12-31 Reinert Korsnes , Knut Ovsthus

This paper proposes an original theory of aging of multicellular organisms. The cells of multicellular organisms, in contrast to unicellular organisms, are burdened with a two- part genome: housekeeping and specialized (multicellular),…

Cell Behavior · Quantitative Biology 2012-08-16 Lev Salnikov

Developing efficient time series anomaly detection techniques is important to maintain service quality and provide early alarms. Generative neural network methods are one class of the unsupervised approaches that are achieving increasing…

Machine Learning · Computer Science 2022-10-07 Yueyan Gu , Farrokh Jazizadeh

This article highlights specific features of biological neurons and their dendritic trees, whose adoption may help advance artificial neural networks used in various machine learning applications. Advancements could take the form of…

Neurons and Cognition · Quantitative Biology 2021-06-15 Spyridon Chavlis , Panayiota Poirazi

Network Intrusion Detection Systems (NIDS) are computer systems which monitor a network with the aim of discerning malicious from benign activity on that network. While a wide range of approaches have met varying levels of success, most…

Artificial Intelligence · Computer Science 2010-07-05 Gianni Tedesco , Uwe Aickelin

Dendrograms are a way to represent evolutionary relationships between organisms. Nowadays, these are inferred based on the comparison of genes or protein sequences by taking into account their differences and similarities. The genetic…

Molecular Networks · Quantitative Biology 2019-09-09 Daniel Gamermann , Arnau Montagud , J. Alberto Conejero , Pedro Fernández de Córdoba , Javier F. Urchueguía