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Neural systems show a modular and typically also a hierarchical organisation across different levels and across different species. Topology relates to function, but it is also influences dynamics as earlier studies showed its effect on…

Neurons and Cognition · Quantitative Biology 2014-05-15 Marcus Kaiser

Investigations of the human connectome have elucidated core features of adult structural networks, particularly the crucial role of hub-regions. However, little is known regarding network organisation of the healthy elderly connectome, a…

Neurons and Cognition · Quantitative Biology 2015-12-15 Alistair Perry , Wei Wen , Anton Lord , Anbupalam Thalamuthu , Perminder Sachdev , Michael Breakspear

The human brain can be considered as complex networks, composed of various regions that continuously exchange their information with each other, forming the brain network graph, from which nodes and edges are extracted using resting-state…

Machine Learning · Computer Science 2025-02-19 Parnian Jalali , Mehran Safayani

A complete understanding of the brain requires an integrated description of the numerous scales of neural organization. It means studying the interplay of genes, synapses, and even whole brain regions which ultimately leads to different…

Neurons and Cognition · Quantitative Biology 2022-08-09 Charley Presigny , Fabrizio De Vico Fallani

When the human brain manifests the birth of organised communication among local and large-scale neuronal populations activity remains undescribed. We report, in resting-state EEG source-estimates of 100 infants at term age, the existence of…

Neurons and Cognition · Quantitative Biology 2020-09-08 Steve Mehrkanoon

We introduce a method that takes advantage of high-quality pretrained multimodal representations to explore fine-grained semantic networks in the human brain. Previous studies have documented evidence of functional localization in the…

Artificial Intelligence · Computer Science 2023-06-07 Cory Efird , Alex Murphy , Joel Zylberberg , Alona Fyshe

The human brain is a complex system defined by multi-way, higher-order interactions invisible to traditional pairwise network models. Although a diverse array of analytical methods has been developed to address this shortcoming, the field…

Quantitative Methods · Quantitative Biology 2025-11-11 Mohamma Reza Salehi , Ali BashirGonbadi , Hamid Soltanian-Zadeh

Large-scale white matter pathways crisscrossing the cortex create a complex pattern of connectivity that underlies human cognitive function. Generative mechanisms for this architecture have been difficult to identify in part because little…

Neurons and Cognition · Quantitative Biology 2015-06-16 Florian Klimm , Danielle S. Bassett , Jean M. Carlson , Peter J. Mucha

We propose to analyze dynamically changing brain networks by decomposing them into three orthogonal components through the Hodge decomposition. We propose to quantify the magnitude and relative strength of each component. We performed…

Neurons and Cognition · Quantitative Biology 2025-07-23 D. Vijay Anand , Anass B El-Yaagoubi , Hernando Ombao , Moo K. Chung

The architecture of biological networks has been reported to exhibit high level of modularity, and to some extent, topological modules of networks overlap with known functional modules. However, how the modular topology of the molecular…

Molecular Networks · Quantitative Biology 2007-09-07 Jing Zhao , Guo-Hui Ding , Lin Tao , Hong Yu , Zhong-Hao Yu , Jian-Hua Luo , Zhi-Wei Cao , Yi-Xue Li

Several networks occurring in real life have modular structures that are arranged in an hierarchical fashion. In this paper, we have proposed a model for such networks, using a stochastic generation method. Using this model we show that,…

Physics and Society · Physics 2009-03-12 Raj Kumar Pan , Sitabhra Sinha

Brain networks has attracted the interests of many neuroscientists. From functional MRI (fMRI) data, statistical tools have been developed to recover brain networks. However, the dimensionality of whole-brain fMRI, usually in hundreds of…

Methodology · Statistics 2014-04-08 Xi Luo

Typical brain networks consist of many peripheral regions and a few highly central ones, i.e. hubs, playing key functional roles in cerebral inter-regional interactions. Studies have shown that networks, obtained from the analysis of…

Neurons and Cognition · Quantitative Biology 2016-07-19 Manlio De Domenico , Shuntaro Sasai , Alex Arenas

Understanding the structural and functional organization of the human brain requires a detailed examination of cortical folding patterns, among which the three-hinge gyrus (3HG) has been identified as a key structural landmark. GyralNet, a…

Neurons and Cognition · Quantitative Biology 2025-04-02 Yan Zhuang , Minheng Chen , Chao Cao , Tong Chen , Jing Zhang , Xiaowei Yu , Yanjun Lyu , Lu Zhang , Tianming Liu , Dajiang Zhu

The ``social brain hypothesis'' for the evolution of large brains in primates has led to evidence for the coevolution of neocortical size and social group sizes. Extrapolation of these findings to modern humans indicated that the equivalent…

Statistical Mechanics · Physics 2007-05-23 W. -X. Zhou , D. Sornette , R. A. Hill , R. I. M. Dunbar

Human parsing is for pixel-wise human semantic understanding. As human bodies are underlying hierarchically structured, how to model human structures is the central theme in this task. Focusing on this, we seek to simultaneously exploit the…

Computer Vision and Pattern Recognition · Computer Science 2020-03-12 Wenguan Wang , Hailong Zhu , Jifeng Dai , Yanwei Pang , Jianbing Shen , Ling Shao

Complex functional brain networks are large networks of brain regions and functional brain connections. Statistical characterizations of these networks aim to quantify global and local properties of brain activity with a small number of…

Neurons and Cognition · Quantitative Biology 2011-07-19 Mikail Rubinov , Olaf Sporns

In the traditional understanding of the neocortex, sensory information flows up a hierarchy of regions, with each level processing increasingly complex features. Information also flows down the hierarchy via a different set of connections.…

Neurons and Cognition · Quantitative Biology 2025-07-09 Jeff Hawkins , Niels Leadholm , Viviane Clay

In cognitive network neuroscience, the connectivity and community structure of the brain network is related to cognition. Much of this research has focused on two measures of connectivity - modularity and flexibility - which frequently have…

Neurons and Cognition · Quantitative Biology 2017-11-28 Aurora I. Ramos-Nuñez , Simon Fischer-Baum , Randi Martin , Qiuhai Yue , Fengdan Ye , Michael W. Deem

Networks that are organized as a hierarchy of modules have been the subject of much research, mainly focusing on algorithms that can extract this community structure from data. The question of why modular hierarchical organizations are so…

Physics and Society · Physics 2019-07-02 Benjamin F. Maier , Cristián Huepe , Dirk Brockmann