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Solving population balance equations, we derive analytical steady-state cell size distributions for single-lineage experiments, such as the mother machine. These experiments are fundamentally different from batch cultures where populations…

Populations and Evolution · Quantitative Biology 2023-09-13 Arthur Genthon

Particles moving along curved trajectories will diffuse if the curvature fluctuates sufficiently in either magnitude or orientation. We consider particles moving at a constant speed with either a fixed or with a Gaussian distributed…

Soft Condensed Matter · Physics 2009-11-10 Andrew D. Rutenberg , Andrew J. Richardson , Claire J. Montgomery

The effect of mechanical interactions between cells in the spreading of bacterial populations was investigated in one-dimensional space. A continuum-mechanics approach, comprising cell migration, proliferation, and exclusion processes, was…

Biological Physics · Physics 2015-12-15 Waipot Ngamsaad , Suthep Suantai

A novel theory for cell differentiation is proposed, based on simulations with interacting artificial cells which have metabolic networks within, and divide into two when the final product is accumulated. Results of simulations with coupled…

adap-org · Physics 2015-06-30 Kunihiko Kaneko , Tetsuya Yomo

Consider a graph where the sites are distributed in space according to a Poisson point process on $\mathbb R^n$. We study a population evolving on this network, with individuals jumping between sites with a rate which decreases…

Probability · Mathematics 2023-04-05 Vincent Bansaye , Michele Salvi

We investigate the long-time evolution of branching diffusion processes (starting with a finite number of particles) in inhomogeneous media. The qualitative behavior of the processes depends on the intensity of the branching. In the…

Probability · Mathematics 2011-08-23 Leonid Koralov

How are granular details of stochastic growth and division of individual cells reflected in smooth deterministic growth of population numbers? We provide an integrated, multiscale perspective of microbial growth dynamics by formulating a…

We consider a continuous-time branching random walk on a multidimensional lattice with two types of particles and an infinite number of initial particles. The main results are devoted to the study of the generating function and the limiting…

Probability · Mathematics 2022-03-16 Iu. Makarova , D. Balashova , S. Molchanov , E. Yarovaya

We are interested in modeling some two-level population dynamics, resulting from the interplay of ecological interactions and phenotypic variation of individuals (or hosts) and the evolution of cells (or parasites) of two types living in…

Probability · Mathematics 2011-01-21 Sylvie Méléard , Sylvie Roelly

We consider individuals of two species distributed over m patches, each with a hosting capacity $d_i N$ , where $d_i \in (0, 1]$. We assume that all the patches are linked by the dispersal of individuals. This work examines how the…

Probability · Mathematics 2026-01-28 Benoît Henry , Céline Wang

Do biological cells sense time by the number of their divisions, a process that ends at senescence? We consider the question "can the cell's perception of time be expressed through the length of the shortest telomere?" The answer is that…

Subcellular Processes · Quantitative Biology 2017-11-15 Zeev Schuss , Kimsy Tor , David Holcman

When an infection spreads in a community, an individual's probability of becoming infected depends on both her susceptibility and exposure to the contagion through contact with others. While one often has knowledge regarding an individual's…

Social and Information Networks · Computer Science 2017-12-05 Maggie Makar , John Guttag , Jenna Wiens

The data we analyze derives from the observation of numerous cells of the bacterium Escherichia coli (E. coli) growing and dividing. Single cells grow and divide to give birth to two daughter cells, that in turn grow and divide. Thus, a…

Applications · Statistics 2015-09-18 Bernard Delyon , Benoîte de Saporta , Nathalie Krell , Lydia Robert

In this paper we consider a model based on branching process theory for the proliferation and the dissemination network of T cells in the adaptive immune response. A multi-type Galton Watson branching process is assumed as the basic…

Quantitative Methods · Quantitative Biology 2015-06-09 Alessandro Boianelli , Antonio Vicino

Various bacterial strains exhibit colonial branching patterns during growth on poor substrates. These patterns reflect bacterial cooperative self-organization and cybernetic processes of communication, regulation and control employed during…

Condensed Matter · Physics 2015-06-25 Ido Golding , Yonathan Kozlovsky , Inon Cohen , Eshel Ben-Jacob

Heterogeneity in the size distribution of cancer cell populations has been recently linked to drug resistance and invasiveness. However, despite many progresses have been made in understanding how such heterogeneous size distributions arise…

Cell Behavior · Quantitative Biology 2023-10-23 Mattia Miotto , Simone Scalise , Marco Leonetti , Giancarlo Ruocco , Giovanna Peruzzi , Giorgio Gosti

For a minimal diffusion process on $ (a,b) $, any possible extension of it to a standard process on $ [a,b] $ is characterized by the characteristic measures of excursions away from the boundary points $ a $ and $ b $. The generator of the…

Probability · Mathematics 2012-04-03 Kouji Yano

A class of stochastic vector-borne infectious disease models is derived and studied. The class type is determined by a general nonlinear incidence rate of the disease. The disease spreads in a highly random environment with variability from…

Populations and Evolution · Quantitative Biology 2020-05-05 Divine Wanduku

The evolution of multicellularity was a major transition in the history of life on earth. Conditions under which multicellularity is favored have been studied theoretically and experimentally. But since the construction of a multicellular…

Populations and Evolution · Quantitative Biology 2018-03-19 Jason Olejarz , Kamran Kaveh , Carl Veller , Martin A. Nowak

Cell motility is one of the most fundamental phenomena underlying biological processes that maintain living organisms alive. Here we introduce a simple model to describe the motility of cells which include not only time-correlated internal…

Biological Physics · Physics 2022-07-13 T. N. Azevedo , L. G. Rizzi
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