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Recent technological advancements have led to the rapid generation of high-throughput biological data, which can be used to address novel scientific questions in broad areas of research. These data can be thought of as a large matrix with…

Computation · Statistics 2021-03-01 Jane W. Liang , Saunak Sen

Researchers now routinely use AI or other machine learning methods to estimate latent variables of economic interest, then plug-in the estimates as covariates in a regression. We show both theoretically and empirically that naively treating…

Econometrics · Economics 2025-05-01 Laura Battaglia , Timothy Christensen , Stephen Hansen , Szymon Sacher

Statistical Relational Learning (SRL) methods have shown that classification accuracy can be improved by integrating relations between samples. Techniques such as iterative classification or relaxation labeling achieve this by propagating…

Information Retrieval · Computer Science 2017-02-13 Immanuel Bayer , Uwe Nagel , Steffen Rendle

We consider a family of problems that are concerned about making predictions for the majority of unlabeled, graph-structured data samples based on a small proportion of labeled samples. Relational information among the data samples, often…

Machine Learning · Computer Science 2019-11-05 Jiaqi Ma , Weijing Tang , Ji Zhu , Qiaozhu Mei

We consider settings where the observations are drawn from a zero-mean multivariate (real or complex) normal distribution with the population covariance matrix having eigenvalues of arbitrary multiplicity. We assume that the eigenvectors of…

Statistics Theory · Mathematics 2009-01-22 N. Raj Rao , James A. Mingo , Roland Speicher , Alan Edelman

We describe a method for inferring linear causal relations among multi-dimensional variables. The idea is to use an asymmetry between the distributions of cause and effect that occurs if both the covariance matrix of the cause and the…

Machine Learning · Statistics 2009-09-25 Dominik Janzing , Patrik O. Hoyer , Bernhard Schoelkopf

Variable selection, also known as feature selection in machine learning, plays an important role in modeling high dimensional data and is key to data-driven scientific discoveries. We consider here the problem of detecting influential…

Methodology · Statistics 2014-09-24 Bo Jiang , Jun S. Liu

Randomized experiments have become a cornerstone of evidence-based decision-making in contexts ranging from online platforms to public health. However, in experimental settings with network interference, a unit's treatment can influence…

Machine Learning · Computer Science 2025-10-22 Sadegh Shirani , Yuwei Luo , William Overman , Ruoxuan Xiong , Mohsen Bayati

Researchers are often interested in understanding the relationship between a set of covariates and a set of response variables. To achieve this goal, the use of regression analysis, either linear or generalized linear models, is largely…

We analyze the complexity of Gibbs samplers for inference in crossed random effect models used in modern analysis of variance. We demonstrate that for certain designs the plain vanilla Gibbs sampler is not scalable, in the sense that its…

Computation · Statistics 2018-03-28 Omiros Papaspiliopoulos , Gareth O. Roberts , Giacomo Zanella

Missing values are unavoidable in many applications of machine learning and present challenges both during training and at test time. When variables are missing in recurring patterns, fitting separate pattern submodels have been proposed as…

Machine Learning · Computer Science 2023-11-27 Lena Stempfle , Ashkan Panahi , Fredrik D. Johansson

Permutation-based partial-correlation tests guarantee finite-sample Type I error control under any fixed design and exchangeable noise, yet their power can collapse when the permutation-augmented design aligns too closely with the covariate…

Methodology · Statistics 2025-06-04 Tianyi Wang , Guanghui Wang , Zhaojun Wang , Changliang Zou

Testing the equality of the covariance matrices of two high-dimensional samples is a fundamental inference problem in statistics. Several tests have been proposed but they are either too liberal or too conservative when the required…

Statistics Theory · Mathematics 2023-01-04 Jin-Ting Zhang , Jingyi Wang , Tianming Zhu

Copulas are a powerful tool for modeling multivariate distributions as they allow to separately estimate the univariate marginal distributions and the joint dependency structure. However, known parametric copulas offer limited flexibility…

Machine Learning · Statistics 2021-11-11 Tim Janke , Mohamed Ghanmi , Florian Steinke

In semi-supervised learning, the prevailing understanding suggests that observing additional unlabeled samples improves estimation accuracy for linear parameters only in the case of model misspecification. In this work, we challenge such a…

Methodology · Statistics 2025-09-03 Kai Chen , Yuqian Zhang

We propose a transfer learning method that utilizes data representations in a semiparametric regression model. Our aim is to perform statistical inference on the parameter of primary interest in the target model while accounting for…

Methodology · Statistics 2024-06-21 Baihua He , Huihang Liu , Xinyu Zhang , Jian Huang

Estimates based on 2x2 tables of frequencies are widely used in statistical applications. However, in many cases these tables are incomplete in the sense that the data required to compute the frequencies for a subset of the cells defining…

Statistics Theory · Mathematics 2018-08-31 Li-Chun Zhang , Raymond L. Chambers

Selecting a good column (or row) subset of massive data matrices has found many applications in data analysis and machine learning. We propose a new adaptive sampling algorithm that can be used to improve any relative-error column selection…

Data Structures and Algorithms · Computer Science 2015-10-15 Saurabh Paul , Malik Magdon-Ismail , Petros Drineas

This paper is concerned with the problem of low rank plus sparse matrix decomposition for big data. Conventional algorithms for matrix decomposition use the entire data to extract the low-rank and sparse components, and are based on…

Numerical Analysis · Computer Science 2017-03-17 Mostafa Rahmani , George Atia

We consider regression in which one predicts a response $Y$ with a set of predictors $X$ across different experiments or environments. This is a common setup in many data-driven scientific fields and we argue that statistical inference can…

Methodology · Statistics 2026-03-23 Niklas Pfister , Evan G. Williams , Jonas Peters , Ruedi Aebersold , Peter Bühlmann