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As the global need for large-scale data storage is rising exponentially, existing storage technologies are approaching their theoretical and functional limits in terms of density and energy consumption, making DNA based storage a potential…

Emerging Technologies · Computer Science 2021-10-12 Yotam Nahum , Eyar Ben-Tolila , Leon Anavy

Typical bio-signal processing front-ends are designed to maximize the quality of the recorded data, to allow faithful reproduction of the signal for monitoring and off-line processing. This leads to designs that have relatively large area…

Signal Processing · Electrical Eng. & Systems 2022-11-24 Mohammadali Sharifshazileh , Giacomo Indiveri

We report an accurate method to determine DNA barcodes from the dwell time measurement of protein tags (barcodes) along the DNA backbone using Brownian dynamics simulation of a model DNA and use a recursive theoretical scheme which improves…

Soft Condensed Matter · Physics 2021-02-09 Swarnadeep Seth , Aniket Bhattacharya

This paper presents a \textit{physics-based} steady-state equivalent circuit model of a two-stage bidirectional inverter. These inverters connect distributed energy resources (DERs), such as photovoltaic (PV) and battery systems, to…

Systems and Control · Electrical Eng. & Systems 2026-01-21 Emmanuel O. Badmus , Amritanshu Pandey

It has been shown that unclocked, recurrent networks of Boolean gates in FPGAs can be used for low-SWaP reservoir computing. In such systems, topology and node functionality of the network are randomly initialized. To create a network that…

Neural and Evolutionary Computing · Computer Science 2024-03-21 Raphael Norman-Tenazas , David Kleinberg , Erik C. Johnson , Daniel P. Lathrop , Matthew J. Roos

DNA is now firmly established as a versatile and robust platform for achieving synthetic nanostructures. While the folding of single molecules into complex structures is routinely achieved through engineering basepair sequences, much less…

Soft Condensed Matter · Physics 2025-05-15 Soumen De Karmakar , Thomas Speck

We study classes of dynamical systems that can be obtained by constructing recursive networks with monotone Boolean functions. Stack filters in nonlinear signal processing are special cases of such systems. We show an analytical connection…

Disordered Systems and Neural Networks · Physics 2009-07-28 Matti Nykter , Juha Kesseli , Ilya Shmulevich

The emerging field of DNA storage employs strands of DNA bases (A/T/C/G) as a storage medium for digital information to enable massive density and durability. The DNA storage pipeline includes: (1) encoding the raw data into sequences of…

Genomics · Quantitative Biology 2025-01-28 Hadas Abraham , Barak Gahtan , Adir Kobovich , Orian Leitersdorf , Alex M. Bronstein , Eitan Yaakobi

We study energy management policies for the compression and transmission of source data collected by an energy-harvesting sensor node with a finite energy buffer (e.g., rechargeable battery) and a finite data buffer (memory) between source…

Information Theory · Computer Science 2014-02-11 Paolo Castiglione , Gerald Matz

We present a new simulation scheme which allows an efficient sampling of reconfigurable supramolecular structures made of polymeric constructs functionalized by reactive binding sites. The algorithm is based on the configurational bias…

Soft Condensed Matter · Physics 2015-06-23 Robin De Gernier , Tine Curk , Galina V. Dubacheva , Ralf P. Richter , Bortolo M. Mognetti

Two models for energy and charge transport and storage in biomolecules are considered. A model based on the discrete nonlinear Schrodinger equation with long-range dispersive interactions (LRI's) between base pairs of DNA is offered for the…

In this work, we report a novel strategy to construct molecular diodes with a record tunable rectification ratio of as high as 10^6 using oxidatively damaged DNA molecules. Being exposed to several endogenous and exogenous events, DNA…

Soft Condensed Matter · Physics 2022-08-01 Abhishek Aggarwal , Supriyo Naskar , Prabal K. Maiti

We demonstrate how the stochastic global optimization scheme of Simulated Annealing can be used to evaluate optimum parameters in the problem of DNA breathing dynamics. The breathing dynamics is followed in accordance with the stochastic…

Statistical Mechanics · Physics 2009-07-29 Pinaki Chaudhury , Ralf Metzler , Suman K Banik

The two strands of a DNA molecule with a repetitive sequence can pair into many different basepairing patterns. For perfectly periodic sequences, early bulk experiments of Poerschke indicate the existence of a sliding process, permitting…

Biomolecules · Quantitative Biology 2007-05-23 Richard A. Neher , Ulrich Gerland

We perform a detailed resource estimate for the prospect of using deep entanglement renormalization ansatz (DMERA) on a fault-tolerant quantum computer, focusing on the regime in which the target system is large. For probing a relatively…

Quantum Physics · Physics 2024-04-18 Joshua Job , Isaac H. Kim , Eric Johnston , Steve Adachi

The central dogma of molecular biology is the principal framework for understanding how nucleic acid information is propagated and used by living systems to create complex biomolecules. Here, by integrating the structural and dynamic…

Biological Physics · Physics 2018-10-04 Jihoon Shin , Junghoon Kim , Sung Ha Park , Tai Hwan Ha

A practical deep neural network's (DNN) evaluation involves thousands of multiply-and-accumulate (MAC) operations. To extend DNN's superior inference capabilities to energy constrained devices, architectures and circuits that minimize…

Emerging Technologies · Computer Science 2020-08-04 Aditya Shukla

Solid-state nanopore and nanopipette sensors are powerful devices for the detection, quantification and structural analysis of biopolymers such as DNA and proteins, especially in carrier-enhanced resistive-pulse sensing. However, hundreds…

Mesoscale and Nanoscale Physics · Physics 2025-10-14 Cengiz J. Khan , Oliver J. Irving , Rand A. Al-Waqfi , Giorgio Ferrari , Tim Albrecht

Flow-driven rotary motors drive functional processes in human society such as windmills and water wheels. Although examples of such rotary motors also feature prominently in cell biology, their synthetic construction at the nanoscale has…

In this paper we discuss the potential of emerging spintorque devices for computing applications. Recent proposals for spinbased computing schemes may be differentiated as all-spin vs. hybrid, programmable vs. fixed, and, Boolean vs.…

Disordered Systems and Neural Networks · Physics 2013-08-19 Kaushik Roy , Mrigank Sharad , Deliang Fan , Karthik Yogendra