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Learning is based on synaptic plasticity, which affects and is driven by neural activity. Because pre- and postsynaptic spiking activity is shaped by randomness, the synaptic weights follow a stochastic process, requiring a probabilistic…

Neurons and Cognition · Quantitative Biology 2026-01-14 Jakob Stubenrauch , Naomi Auer , Richard Kempter , Benjamin Lindner

The apparent stochasticity of in-vivo neural circuits has long been hypothesized to represent a signature of ongoing stochastic inference in the brain. More recently, a theoretical framework for neural sampling has been proposed, which…

Neurons and Cognition · Quantitative Biology 2017-03-14 Mihai A. Petrovici , Ilja Bytschok , Johannes Bill , Johannes Schemmel , Karlheinz Meier

General results from statistical learning theory suggest to understand not only brain computations, but also brain plasticity as probabilistic inference. But a model for that has been missing. We propose that inherently stochastic features…

Neural and Evolutionary Computing · Computer Science 2016-02-17 David Kappel , Stefan Habenschuss , Robert Legenstein , Wolfgang Maass

We propose a scalable semiparametric Bayesian model to capture dependencies among multiple neurons by detecting their co-firing (possibly with some lag time) patterns over time. After discretizing time so there is at most one spike at each…

Applications · Statistics 2015-06-22 Babak Shahbaba , Bo Zhou , Shiwei Lan , Hernando Ombao , David Moorman , Sam Behseta

Statistical analysis and inferences on spike trains are one of the central topics in neural coding. It is of great interest to understand the underlying distribution and geometric structure of given spike train data. However, a fundamental…

Neurons and Cognition · Quantitative Biology 2015-06-11 Sergiusz Wesolowski , Alexandre A. Nikonov , Robert J. Contreras , Wei Wu

We suggest a mechanism based on spike time dependent plasticity (STDP) of synapses to store, retrieve and predict temporal sequences. The mechanism is demonstrated in a model system of simplified integrate-and-fire type neurons densely…

Adaptation and Self-Organizing Systems · Physics 2009-11-07 Thomas Nowotny , Misha I. Rabinovich , Henry D. I. Abarbanel

Piecewise-deterministic Markov processes (PDMPs) offer a powerful stochastic modeling framework that combines deterministic trajectories with random perturbations at random times. Estimating their local characteristics (particularly the…

Methodology · Statistics 2025-12-29 Romain Azaïs , Solune Denis

Entropy rate of sequential data-streams naturally quantifies the complexity of the generative process. Thus entropy rate fluctuations could be used as a tool to recognize dynamical perturbations in signal sources, and could potentially be…

Information Theory · Computer Science 2014-03-24 Ishanu Chattopadhyay , Hod Lipson

The intricate relations between elements in natural and human-made systems sustain the complex processes that shape our world, forming multiscale networks of interactions. These networks can be represented as graphs composed of nodes…

Disordered Systems and Neural Networks · Physics 2026-03-20 M. Ángeles Serrano

Recent work emphasizes that the maximum entropy principle provides a bridge between statistical mechanics models for collective behavior in neural networks and experiments on networks of real neurons. Most of this work has focused on…

Neurons and Cognition · Quantitative Biology 2015-06-05 Gasper Tkacik , Olivier Marre , Thierry Mora , Dario Amodei , Michael J. Berry , William Bialek

Discovering frequent episodes in event sequences is an interesting data mining task. In this paper, we argue that this framework is very effective for analyzing multi-neuronal spike train data. Analyzing spike train data is an important…

Databases · Computer Science 2008-03-10 Debprakash Patnaik , P. S. Sastry , K. P. Unnikrishnan

Fitting network models to neural activity is an important tool in neuroscience. A popular approach is to model a brain area with a probabilistic recurrent spiking network whose parameters maximize the likelihood of the recorded activity.…

Machine Learning · Statistics 2021-11-16 Guillaume Bellec , Shuqi Wang , Alireza Modirshanechi , Johanni Brea , Wulfram Gerstner

Spiking activity from populations of neurons display causal interactions and memory effects. Therefore, they are expected to show some degree of irreversibility in time. Motivated by the spike train statistics, in this paper we build a…

Biological Physics · Physics 2015-12-07 Rodrigo Cofre , Cesar Maldonado

Spiking neural networks (SNNs) are distributed trainable systems whose computing elements, or neurons, are characterized by internal analog dynamics and by digital and sparse synaptic communications. The sparsity of the synaptic spiking…

Machine Learning · Computer Science 2020-01-08 Hyeryung Jang , Osvaldo Simeone , Brian Gardner , André Grüning

Spiking neural network is a type of artificial neural network in which neurons communicate between each other with spikes. Spikes are identical Boolean events characterized by the time of their arrival. A spiking neuron has internal…

Neural and Evolutionary Computing · Computer Science 2016-02-16 Oleg Y. Sinyavskiy

One of the paramount challenges in neuroscience is to understand the dynamics of individual neurons and how they give rise to network dynamics when interconnected. Historically, researchers have resorted to graph theory, statistics, and…

Neurons and Cognition · Quantitative Biology 2019-02-08 Jean-Baptiste Bardin , Gard Spreemann , Kathryn Hess

Spike generation in neurons produces a temporal point process, whose statistics is governed by intrinsic phenomena and the external incoming inputs to be coded. In particular, spike-evoked adaptation currents support a slow temporal process…

Neurons and Cognition · Quantitative Biology 2016-10-31 Eugenio Urdapilleta

When brain signals are recorded in an electroencephalogram or some similar large-scale record of brain activity, oscillatory patterns are typically observed that are thought to reflect the aggregate electrical activity of the underlying…

Neurons and Cognition · Quantitative Biology 2013-06-04 Andre Nathan , Valmir C. Barbosa

Advances in neuroscience have enabled researchers to measure the activities of large numbers of neurons simultaneously in behaving animals. We have access to the fluorescence of each of the neurons which provides a first-order approximation…

Neurons and Cognition · Quantitative Biology 2023-07-21 Abhisek Chakraborty

The relationship between a neuron's complex inputs and its spiking output defines the neuron's coding strategy. This is frequently and effectively modeled phenomenologically by one or more linear filters that extract the components of the…

Neurons and Cognition · Quantitative Biology 2011-11-02 Michael Famulare , Adrienne L. Fairhall