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Related papers: Triggering up states in all-to-all coupled neurons

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Many types of mammalian cells exert active contractile forces and mechanically deform their elastic substrate, to accomplish biological functions such as cell migration. These substrate deformations provide a mechanism by which cells can…

Soft Condensed Matter · Physics 2022-02-22 Subhaya Bose , Patrick S. Noerr , Ajay Gopinathan , Arvind Gopinath , Kinjal Dasbiswas

We study molecular dynamics within populations of diffusively coupled cells under the assumption of fast diffusive exchange. As a technical tool, we propose conditions on boundedness and ultimate boundedness for systems with a singular…

Cell Behavior · Quantitative Biology 2012-12-19 Steffen Waldherr , Frank Allgöwer

Cortical neurons are characterized by irregular firing and a broad distribution of rates. The balanced state model explains these observations with a cancellation of mean excitatory and inhibitory currents, which makes fluctuations drive…

Neurons and Cognition · Quantitative Biology 2020-10-15 Alessandro Sanzeni , Mark H Histed , Nicolas Brunel

We investigate the dynamics of a network consisting of an array of identical cortical units with nearest neighbor interactions under periodic arousal. Each unit consists of two interconnected populations of neurons tuned to a state in which…

Neurons and Cognition · Quantitative Biology 2019-02-12 Leandro M. Alonso

The study of cortical dynamics during different states such as decision making, sleep and movement, is an important topic in Neuroscience. Modelling efforts aim to relate the neural rhythms present in cortical recordings to the underlying…

Neurons and Cognition · Quantitative Biology 2025-12-10 Daniele Avitabile , Gabriel J. Lord , Khadija Meddouni

Sequences of events in noise-driven excitable systems with slow variables often show serial correlations among their intervals of events. Here, we employ a master equation for general non-renewal processes to calculate the interval and…

Biological Physics · Physics 2011-05-23 Farzad Farkhooi , Eilif Muller , Martin P. Nawrot

We report a noise induced delay of bifurcation in a simple pulse-coupled neural circuit. We study the behavior of two neural oscillators, each individually governed by saddle-node dynamics, with reciprocal excitatory synaptic connections.…

Biological Physics · Physics 2007-05-23 Boris Gutkin , Tim Hely , Juergen Jost

In the last century, most sensorimotor studies of cortical neurons relied on average firing rates. Rate coding is efficient for fast sensorimotor processing that occurs within a few seconds. Much less is known about the neural mechanisms…

Neurons and Cognition · Quantitative Biology 2026-05-01 Terrence J. Sejnowski

We study a system of dynamical units, each of which shows excitable or oscillatory behavior, depending on the choice of parameters. When we couple these units with repressive bonds, we can control the duration of collective oscillations for…

Molecular Networks · Quantitative Biology 2014-02-06 Darka Labavic , Hildegard Meyer-Ortmanns

Metastable brain dynamics are characterized by abrupt, jump-like modulations so that the neural activity in single trials appears to unfold as a sequence of discrete, quasi-stationary states. Evidence that cortical neural activity unfolds…

Neurons and Cognition · Quantitative Biology 2019-06-20 Giancarlo La Camera , Alfredo Fontanini , Luca Mazzucato

Local networks of neurons are nonlinear systems driven by synaptic currents elicited by its own spiking activity and the input received from other brain areas. Synaptic currents are well approximated by correlated Gaussian noise. Besides,…

Neurons and Cognition · Quantitative Biology 2024-04-09 Gianni Valerio Vinci , Maurizio Mattia

We study the versatile performance of networks of coupled circuits. Each of these circuits is composed of a positive and a negative feedback loop in a motif that is frequently found in genetic and neural networks. When two of these circuits…

Adaptation and Self-Organizing Systems · Physics 2015-06-22 Darka Labavić , Hildegard Meyer-Ortmanns

The occurrence of sleep passed through the evolutionary sieve and is widespread in animal species. Sleep is known to be beneficial to cognitive and mnemonic tasks, while chronic sleep deprivation is detrimental. Despite the importance of…

Neurons and Cognition · Quantitative Biology 2019-11-19 Cristiano Capone , Elena Pastorelli , Bruno Golosio , Pier Stanislao Paolucci

Flexible modulation of temporal dynamics in neural sequences underlies many cognitive processes. For instance, we can adaptively change the speed of motor sequences and speech. While such flexibility is influenced by various factors such as…

Neurons and Cognition · Quantitative Biology 2025-04-15 Tomoki Kurikawa , Kunihiko Kaneko

Cortical neurons include many sub-cellular processes, operating at multiple timescales, which may affect their response to stimulation through non-linear and stochastic interaction with ion channels and ionic concentrations. Since new…

Neurons and Cognition · Quantitative Biology 2014-05-01 Daniel Soudry , Ron Meir

We analyze the stability of standing pulse solutions of a neural network integro-differential equation. The network consists of a coarse-grained layer of neurons synaptically connected by lateral inhibition with a non-saturating nonlinear…

Neurons and Cognition · Quantitative Biology 2007-05-23 Yixin Guo , Carson C. Chow

We here study a network of synaptic relations mingling excitatory and inhibitory neuron nodes that displays oscillations quite similar to electroencephalogram (EEG) brain waves, and identify abrupt variations brought about by swift synaptic…

Neurons and Cognition · Quantitative Biology 2021-02-17 Jorge Pretel , Joaquin J. Torres , J. Marro

We study the statistics of spike trains of simultaneously recorded grid cells in freely behaving rats. We evaluate pairwise correlations between these cells and, using a generalized linear model (kinetic Ising model), study their functional…

Neurons and Cognition · Quantitative Biology 2015-06-19 Benjamin Dunn , Maria Mørreaunet , Yasser Roudi

The dynamics of three mutually coupled cortical neurons with time delays in the coupling are explored numerically and analytically. The neurons are coupled in a line, with the middle neuron sending a somewhat stronger projection to the…

Chaotic Dynamics · Physics 2011-01-25 Alexandra S. Landsman , Ira B. Schwartz

A pervasive challenge in neuroscience is testing whether neuronal connectivity changes over time due to specific causes, such as stimuli, events, or clinical interventions. Recent hardware innovations and falling data storage costs enable…

Neurons and Cognition · Quantitative Biology 2024-01-05 Johan Medrano , Karl J. Friston , Peter Zeidman