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Observability is a modelling property that describes the possibility of inferring the internal state of a system from observations of its output. A related property, structural identifiability, refers to the theoretical possibility of…

Quantitative Methods · Quantitative Biology 2018-12-12 Alejandro F. Villaverde

In this paper, the relationship between probabilistic graphical models, in particular Bayesian networks, and causal diagrams, also called structural causal models, is studied. Structural causal models are deterministic models, based on…

Artificial Intelligence · Computer Science 2026-04-24 Peter J. F. Lucas , Eleonora Zullo , Fabio Stella

In a variety of disciplines such as social sciences, psychology, medicine and economics, the recorded data are considered to be noisy measurements of latent variables connected by some causal structure. This corresponds to a family of…

Machine Learning · Computer Science 2014-08-12 Ricardo Silva , Robert B. Gramacy

In a variety of disciplines such as social sciences, psychology, medicine and economics, the recorded data are considered to be noisy measurements of latent variables connected by some causal structure. This corresponds to a family of…

Machine Learning · Computer Science 2010-03-15 Ricardo Silva , Robert B. Gramacy

A graphical model is a statistical model that is associated to a graph whose nodes correspond to variables of interest. The edges of the graph reflect allowed conditional dependencies among the variables. Graphical models admit…

Methodology · Statistics 2016-06-09 Mathias Drton , Marloes H. Maathuis

Elimination of unknowns in a system of differential equations is often required when analysing (possibly nonlinear) dynamical systems models, where only a subset of variables are observable. One such analysis, identifiability, often relies…

Algebraic Geometry · Mathematics 2022-11-28 Ruiwen Dong , Christian Goodbrake , Heather A Harrington , Gleb Pogudin

A parameter of a mathematical model is structurally identifiable if it can be determined from noiseless experimental data. Here, we examine the identifiability properties of two important classes of linear compartmental models:…

The successful application of modern machine learning for time series classification is often hampered by limitations in quality and quantity of available training data. To overcome these limitations, available domain expert knowledge in…

Machine Learning · Computer Science 2025-02-07 Janis Norden , Elisa Oostwal , Michael Chappell , Peter Tino , Kerstin Bunte

The paper gives an overview of recent advances in structural equation modeling. A structural equation model is a multivariate statistical model that is determined by a mixed graph, also known as a path diagram. Our focus is on the…

Statistics Theory · Mathematics 2016-12-20 Mathias Drton

In this paper, we prove that some Gaussian structural equation models with dependent errors having equal variances are identifiable from their corresponding Gaussian distributions. Specifically, we prove identifiability for the Gaussian…

Machine Learning · Statistics 2018-08-30 Jose M. Peña

A fundamental challenge of scientific research is inferring causal relations based on observed data. One commonly used approach involves utilizing structural causal models that postulate noisy functional relations among interacting…

Methodology · Statistics 2024-08-13 David Strieder , Mathias Drton

Estimating the governing equation parameter values is essential for integrating experimental data with scientific theory to understand, validate, and predict the dynamics of complex systems. In this work, we propose a new method for…

Dynamical Systems · Mathematics 2025-06-27 Cristian López , Keegan J. Moore

In this paper we present a sufficient condition that guarantees identifiability of linear network dynamic systems exhibiting continuous-time weighted consensus protocols with acyclic structure. Each edge of the underlying network graph…

Systems and Control · Computer Science 2014-12-03 Seyedbehzad Nabavi , Aranya Chakrabortty , Pramod P. Khargonekar

Linear structural equation models represent direct causal effects as directed edges and confounding factors as bidirected edges. An open problem is to identify the causal parameters from correlations between the nodes. We investigate…

Artificial Intelligence · Computer Science 2022-03-07 Benito van der Zander , Marcel Wienöbst , Markus Bläser , Maciej Liśkiewicz

Stochasticity plays a key role in many biological systems, necessitating the calibration of stochastic mathematical models to interpret associated data. For model parameters to be estimated reliably, it is typically the case that they must…

Differential equation models are crucial to scientific processes. The values of model parameters are important for analyzing the behaviour of solutions. A parameter is called globally identifiable if its value can be uniquely determined…

Quantitative Methods · Quantitative Biology 2024-02-07 Helen Byrne , Heather Harrington , Alexey Ovchinnikov , Gleb Pogudin , Hamid Rahkooy , Pedro Soto

While hidden class models of various types arise in many statistical applications, it is often difficult to establish the identifiability of their parameters. Focusing on models in which there is some structure of independence of some of…

Statistics Theory · Mathematics 2009-09-01 Elizabeth S. Allman , Catherine Matias , John A. Rhodes

A key step in mechanistic modelling of dynamical systems is to conduct a structural identifiability analysis. This entails deducing which parameter combinations can be estimated from a given set of observed outputs. The standard…

Optimization and Control · Mathematics 2026-03-30 Johannes G Borgqvist , Alexander P Browning , Fredrik Ohlsson , Ruth E Baker

Structural identifiability concerns the question of which unknown parameters of a model can be recovered from (perfect) input-output data. If all of the parameters of a model can be recovered from data, the model is said to be identifiable.…

Systems and Control · Electrical Eng. & Systems 2025-06-11 Nicolette Meshkat , Alexey Ovchinnikov , Thomas Scanlon

Linear structural equation models relate the components of a random vector using linear interdependencies and Gaussian noise. Each such model can be naturally associated with a mixed graph whose vertices correspond to the components of the…