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The problem of the directionality of genome evolution is studied from the information-theoretic view. We propose that the function-coding information quantity of a genome always grows in the course of evolution through sequence duplication,…

Genomics · Quantitative Biology 2011-08-05 Liaofu Luo

There is an intrinsic relationship between the molecular evolution in primordial period and the properties of genomes and proteomes of contemporary species. The genomic data may help us understand the driving force of evolution of life at…

Genomics · Quantitative Biology 2009-11-25 Dirson Jian Li , Shengli Zhang

Neural codes appear efficient. Naturally, neuroscientists contend that an efficient process is responsible for generating efficient codes. They argue that natural selection is the efficient process that generates those codes. Although…

Neurons and Cognition · Quantitative Biology 2022-03-21 Han Kim

In order to make a case for or against a trend in the evolution of complexity in biological evolution, complexity needs to be both rigorously defined and measurable. A recent information-theoretic (but intuitively evident) definition…

Biological Physics · Physics 2016-09-08 Christoph Adami , Charles Ofria , Travis C. Collier

Software is the key crosscutting technology that enables advances in mathematics, computer science, and domain-specific science and engineering to achieve robust simulations and analysis for science, engineering, and other research fields.…

Evolution and learning are two of the fundamental mechanisms by which life adapts in order to survive and to transcend limitations. These biological phenomena inspired successful computational methods such as evolutionary algorithms and…

Neural and Evolutionary Computing · Computer Science 2019-05-10 Jan Schuchardt , Vladimir Golkov , Daniel Cremers

This chapter investigates the evolutionary ecology of software, focusing on the symbiotic relationship between software and innovation. An interplay between constraints, tinkering, and frequency-dependent selection drives the complex…

Software Engineering · Computer Science 2025-12-03 Sergi Valverde , Blai Vidiella , Salva Duran-Nebreda

Distribution can be a feature of the software evolution process. In other words, temporally and spatially distributed teams and organizations can develop and work on a software application. The simplest case is to outsource production and…

Software Engineering · Computer Science 2022-05-02 Mohammad Reza Besharati

The human microbiome is the ensemble of genes in the microbes that live inside and on the surface of humans. Because microbial sequencing information is now much easier to come by than phenotypic information, there has been an explosion of…

Populations and Evolution · Quantitative Biology 2014-07-08 Frederick A Matsen

In Search Based Software Engineering, Genetic Programming has been used for bug fixing, performance improvement and parallelisation of programs through the modification of source code. Where an evolutionary computation algorithm, such as…

Neural and Evolutionary Computing · Computer Science 2012-11-22 Brendan Cody-Kenny , Stephen Barrett

In computer science, we can theoretically neatly separate transmission and processing of information, hardware and software, and programs and their inputs. This is much more intricate in biology, Nevertheless, I argue that Shannon's concept…

Populations and Evolution · Quantitative Biology 2020-11-02 Jürgen Jost

``The purpose of life is to obtain knowledge, use it to live with as much satisfaction as possible, and pass it on with improvements and modifications to the next generation.'' This may sound philosophical, and the interpretation of words…

Quantum Physics · Physics 2007-05-23 Apoorva Patel

We discuss a model of genome as a program with functional architecture and consider the approach to Darwinian evolution as a learning problem for functional programming. In particular we introduce a model of learning for some class of…

Neural and Evolutionary Computing · Computer Science 2020-06-18 S. V. Kozyrev

Because genomes are products of natural processes rather than intelligent design, all genomes contain functional and nonfunctional parts. The fraction of the genome that has no biological function is called rubbish DNA. Rubbish DNA consists…

Genomics · Quantitative Biology 2016-01-25 Dan Graur

The modeling of time series is becoming increasingly critical in a wide variety of applications. Overall, data evolves by following different patterns, which are generally caused by different user behaviors. Given a time series, we define…

Machine Learning · Computer Science 2022-07-13 Wenjie Hu , Jianping Huang , Liang Wu , Yang Yang , Zongtao Liu , Zhanlin Sun , Bingshen Yao , Ke Chen

A central goal of evolutionary biology is to explain the origins and distribution of diversity across life. Beyond species or genetic diversity, we also observe diversity in the circuits (genetic or otherwise) underlying complex functional…

Populations and Evolution · Quantitative Biology 2018-06-06 Ali Tehrani-Saleh , Thomas LaBar , Christoph Adami

Ecosystems are complex and dynamic systems. Over billions of years, they have developed advanced capabilities to provide stable functions, despite changes in their environment. In this paper, we argue that the laws of organization and…

Software Engineering · Computer Science 2012-07-11 Benoit Baudry , Martin Monperrus

Program synthesis is the task of automatically generating a program consistent with a given specification. A natural way to specify programs is to provide examples of desired input-output behavior, and many current program synthesis…

Machine Learning · Computer Science 2020-07-28 Alexander Suh , Yuval Timen

The problem of the directionality of genome evolution is studied. Based on the analysis of C-value paradox and the evolution of genome size we propose that the function-coding information quantity of a genome always grows in the course of…

Genomics · Quantitative Biology 2015-05-13 Liaofu Luo

Evolution has fascinated quantitative and physical scientists for decades: how can the random process of mutation, recombination, and duplication of genetic information generate the diversity of life? What determines the rate of evolution?…

Populations and Evolution · Quantitative Biology 2018-04-23 Richard A. Neher , Aleksandra M. Walczak