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De novo genome assembly is challenging in highly repetitive regions; however, reference-guided assemblers often suffer from bias. We propose a framework for pangenome-guided sequence assembly, which can resolve short-read data in complex…

Quantum Physics · Physics 2026-02-11 Josh Cudby , James Bonfield , Chenxi Zhou , Richard Durbin , Sergii Strelchuk

Despite the promising performance of convolutional neural networks (CNNs) in brain tumor diagnosis from magnetic resonance imaging (MRI), their integration into the clinical workflow has been limited. That is mainly due to the fact that the…

Image and Video Processing · Electrical Eng. & Systems 2024-11-04 Sara Ketabi , Matthias W. Wagner , Cynthia Hawkins , Uri Tabori , Birgit Betina Ertl-Wagner , Farzad Khalvati

Subject to intricate environmental variables, the precise classification of jamming signals holds paramount significance in the effective implementation of anti-jamming strategies within communication systems. In light of this imperative,…

Signal Processing · Electrical Eng. & Systems 2024-06-27 Xuhui Ding , Yue Zhang , Gaoyang Li , Xiaozheng Gao , Neng Ye , Dusit Niyato , Kai Yang

Computer-aided tumor detection has shown great potential in enhancing the interpretation of over 80 million CT scans performed annually in the United States. However, challenges arise due to the rarity of CT scans with tumors, especially…

Image and Video Processing · Electrical Eng. & Systems 2024-09-11 Qi Chen , Yuxiang Lai , Xiaoxi Chen , Qixin Hu , Alan Yuille , Zongwei Zhou

This work introduces a novel framework for brain tumor segmentation leveraging pre-trained GANs and Unet architectures. By combining a global anomaly detection module with a refined mask generation network, the proposed model accurately…

Image and Video Processing · Electrical Eng. & Systems 2025-06-27 Qifei Cui , Xinyu Lu

Ensuring high-quality data is paramount for maximizing the performance of machine learning models and business intelligence systems. However, challenges in data quality, including noise in data capture, missing records, limited data…

Machine Learning · Computer Science 2024-05-30 Paulo Neves , Joerg K. Wegner , Philippe Schwaller

Artificial Neural Networks (ANN) comprise important symmetry properties, which can influence the performance of Monte Carlo methods in Neuroevolution. The problem of the symmetries is also known as the competing conventions problem or…

Neural and Evolutionary Computing · Computer Science 2011-07-25 Onay Urfalioglu , Orhan Arikan

Motivation: Despite significant advances in Third-Generation Sequencing (TGS) technologies, Next-Generation Sequencing (NGS) technologies remain dominant in the current sequencing market. This is due to the lower error rates and richer…

Information Theory · Computer Science 2023-04-04 Jia Wang , Yi Niu , Tianyi Xu , Mingming Ma , Dahua Gao , Guangming Shi

To improve patient survival and treatment outcomes, early diagnosis of brain tumors is an essential task. It is a difficult task to evaluate the magnetic resonance imaging (MRI) images manually. Thus, there is a need for digital methods for…

Computer Vision and Pattern Recognition · Computer Science 2021-01-05 Ginni Garg , Ritu Garg

Recent advances in conditional generative modeling have introduced Continuous conditional Generative Adversarial Network (CcGAN) and Continuous Conditional Diffusion Model (CCDM) for estimating high-dimensional data distributions…

Machine Learning · Computer Science 2026-02-04 Xin Ding , Yun Chen , Yongwei Wang , Kao Zhang , Sen Zhang , Peibei Cao , Xiangxue Wang

Skin Cancer is one of the most deathful of all the cancers. It is bound to spread to different parts of the body on the off chance that it is not analyzed and treated at the beginning time. It is mostly because of the abnormal growth of…

Machine Learning · Computer Science 2019-12-10 Rishu Garg , Saumil Maheshwari , Anupam Shukla

Cancer is one of the leading causes of death worldwide, and head and neck (H&N) cancer is amongst the most prevalent types. Positron emission tomography and computed tomography are used to detect, segment and quantify the tumor region.…

Image and Video Processing · Electrical Eng. & Systems 2022-05-13 Ikboljon Sobirov , Otabek Nazarov , Hussain Alasmawi , Mohammad Yaqub

This study proposes CGRclust, a novel combination of unsupervised twin contrastive clustering of Chaos Game Representations (CGR) of DNA sequences, with convolutional neural networks (CNNs). To the best of our knowledge, CGRclust is the…

Genomics · Quantitative Biology 2024-11-14 Fatemeh Alipour , Kathleen A. Hill , Lila Kari

Recent tumor genome sequencing confirmed that one tumor often consists of multiple cell subpopulations (clones) which bear different, but related, genetic profiles such as mutation and copy number variation profiles. Thus far, one tumor has…

Molecular Networks · Quantitative Biology 2014-09-09 Edwin Wang , Jinfeng Zou , Naif Zaman , Lenore K. Beitel , Mark Trifiro , Miltiadis Paliouras

Changes in the number of copies of certain parts of the genome, known as copy number alterations (CNAs), due to somatic mutation processes are a hallmark of many cancers. This genomic complexity is known to be associated with poorer…

Genomics · Quantitative Biology 2024-08-26 Charles Gadd , Christopher Yau

Deploying deep learning-based imaging tools across various clinical sites poses significant challenges due to inherent domain shifts and regulatory hurdles associated with site-specific fine-tuning. For histopathology, stain normalization…

Identification of genes that initiate cell anomalies and cause cancer in humans is among the important fields in the oncology researches. The mutation and development of anomalies in these genes are then transferred to other genes in the…

Molecular Networks · Quantitative Biology 2023-03-03 Mostafa Akhavan Safar , Babak Teimourpour , Abbas Nozari-Dalini

Using histopathological images to automatically classify cancer is a difficult task for accurately detecting cancer, especially to identify metastatic cancer in small image patches obtained from larger digital pathology scans. Computer…

Image and Video Processing · Electrical Eng. & Systems 2020-11-16 Guanwen Qiu , Xiaobing Yu , Baolin Sun , Yunpeng Wang , Lipei Zhang

Quantum computers with hundreds of qubits will be available soon. Unfortunately, high device error-rates pose a significant challenge in using these near-term quantum systems to power real-world applications. Executing a program on existing…

Quantum Physics · Physics 2022-08-22 Swamit Tannu , Poulami Das , Ramin Ayanzadeh , Moinuddin Qureshi

Consistency Models (CMs) have shown promise for efficient one-step generation. However, most existing CMs rely on manually designed discretization schemes, which can cause repeated adjustments for different noise schedules and datasets. To…

Machine Learning · Computer Science 2025-10-21 Jiayu Bai , Zhanbo Feng , Zhijie Deng , Tianqi Hou , Robert C. Qiu , Zenan Ling