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Support vector machines (SVMs) have been successful in solving many computer vision tasks including image and video category recognition especially for small and mid-scale training problems. The principle of these non-parametric models is…
Identification and characterization of large protein complexes is a mainstay of biochemical toolboxes. Utilization of cross-linking chemicals can facilitate the capture and identification of transient or weak interactions of a transient…
In the analysis of spatially resolved transcriptomics data, detecting spatially variable genes (SVGs) is crucial. Numerous computational methods exist, but varying SVG definitions and methodologies lead to incomparable results. We review 33…
Skeleton-based human action recognition has attracted much attention with the prevalence of accessible depth sensors. Recently, graph convolutional networks (GCNs) have been widely used for this task due to their powerful capability to…
Graph convolutional networks (GCNs) have been very successful in skeleton-based human action recognition where the sequence of skeletons is modeled as a graph. However, most of the GCN-based methods in this area train a deep feed-forward…
Exploiting the wealth of imaging and non-imaging information for disease prediction tasks requires models capable of representing, at the same time, individual features as well as data associations between subjects from potentially large…
Protein representation learning aims to learn informative protein embeddings capable of addressing crucial biological questions, such as protein function prediction. Although sequence-based transformer models have shown promising results by…
In this paper, we discuss the issues in automatic recognition of vowels in Persian language. The present work focuses on new statistical method of recognition of vowels as a basic unit of syllables. First we describe a vowel detection…
International Classification of Disease (ICD) codes are widely used for encoding diagnoses in electronic health records (EHR). Automated methods have been developed over the years for predicting biomedical responses using EHR that borrow…
We tackle classification based on brain connectivity derived from diffusion magnetic resonance images. We propose a machine-learning model inspired by graph convolutional networks (GCNs), which takes a brain connectivity input graph and…
Single-cell gene expression measurements offer opportunities in deriving mechanistic understanding of complex diseases, including cancer. However, due to the complex regulatory machinery of the cell, gene regulatory network (GRN) model…
The methodology of community detection can be divided into two principles: imposing a network model on a given graph, or optimizing a designed objective function. The former provides guarantees on theoretical detectability but falls short…
We propose a novel deep neural network architecture to integrate imaging and genetics data, as guided by diagnosis, that provides interpretable biomarkers. Our model consists of an encoder, a decoder and a classifier. The encoder learns a…
Graph neural networks (GNNs) have emerged as powerful tools for learning protein structures by capturing spatial relationships at the residue level. However, existing GNN-based methods often face challenges in learning multiscale…
The identification of melanoma involves an integrated analysis of skin lesion images acquired using the clinical and dermoscopy modalities. Dermoscopic images provide a detailed view of the subsurface visual structures that supplement the…
Classification is one of the main areas of pattern recognition research, and within it, Support Vector Machine (SVM) is one of the most popular methods outside of field of deep learning -- and a de-facto reference for many Machine Learning…
Most approaches to prediction of protein function from primary structure are based on similarity between the query sequence and sequences of known function. This approach, however, disregards the occurrence of gene duplication (paralogy) or…
Motivation: Identifying interaction clusters of large gene regulatory networks (GRNs) is critical for its further investigation, while this task is very challenging, attributed to data noise in experiment data, large scale of GRNs, and…
Investigation on the electrocardiogram (ECG) signals is an essential way to diagnose heart disease since the ECG process is noninvasive and easy to use. This work presents a supraventricular arrhythmia prediction model consisting of a few…
The shared topology of human skeletons motivated the recent investigation of graph convolutional network (GCN) solutions for action recognition. However, most of the existing GCNs rely on the binary connection of two neighboring vertices…