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This work explores four nonlinear classical models of neural oscillators, the Hodgkin-Huxley model, the Fitzhugh-Nagumo model, the Morris-Lecar model, and the Hindmarsh-Rose model. Nonlinear contraction theory is used to develop observers…

Neurons and Cognition · Quantitative Biology 2013-10-03 Ranjeetha Bharath , Jean-Jacques Slotine

This paper presents an investigation of the dynamics of two coupled non-identical FitzHugh-Nagumo neurons with quadratic term and delayed synaptic connection. We consider coupling strength and time delay as bifurcation parameters, and try…

Chaotic Dynamics · Physics 2016-02-29 Niloofar Farajzadeh Tehrani , MohammadReza Razvan

The stochastic FitzHugh-Nagumo (FHN) model is a two-dimensional nonlinear stochastic differential equation with additive degenerate noise, whose first component, the only one observed, describes the membrane voltage evolution of a single…

Computation · Statistics 2024-10-08 Adeline Samson , Massimiliano Tamborrino , Irene Tubikanec

In this article, we study the FitzHugh-Nagumo $(1,1)$--fast-slow system where the vector fields associated to the slow/fast equations come from the reduction of the Hodgin-Huxley model for the nerve impulse. After deriving dynamical…

Dynamical Systems · Mathematics 2025-06-19 Bruno F. F. Gonçalves , Isabel S. Labouriau , Alexandre A. P. Rodrigues

Being an example for a relaxation oscillator, the FitzHugh-Nagumo model has been widely employed for describing the generation of action potentials. In this paper, we begin with a biological interpretation of what the subsequent…

Numerical Analysis · Mathematics 2025-01-31 Burcu Gürbüz , Aytül Gökçe , Mahmut Modanlı

We study the dynamics of a low-dimensional system of coupled model neurons as a step towards understanding the vastly complex network of neurons in the brain. We analyze the bifurcation structure of a system of two model neurons with…

Dynamical Systems · Mathematics 2019-03-27 Elizabeth N. Davison , Zahra Aminzare , Biswadip Dey , Naomi Ehrich Leonard

Serotonergic, noradrenergic and dopaminergic brainstem (including midbrain) neurons, often exhibit spontaneous and fairly regular spiking with frequencies of order a few Hz, though dopaminergic and noradrenergic neurons only exhibit such…

Neurons and Cognition · Quantitative Biology 2017-04-18 Henry C. Tuckwell , Ying Zhou , Nicholas J. Penington

We derive the mean-field equations arising as the limit of a network of interacting spiking neurons, as the number of neurons goes to infinity. The neurons belong to a fixed number of populations and are represented either by the…

Neurons and Cognition · Quantitative Biology 2016-11-25 Javier Baladron , Diego Fasoli , Olivier Faugeras , Jonathan Touboul

This paper presents an investigation of the dynamics of two coupled non-identical FitzHugh-Nagumo neurons with delayed synaptic connection. We consider coupling strength and time delay as bifurcation parameters, and try to classify all…

Dynamical Systems · Mathematics 2015-10-07 Niloofar Farajzadeh Tehrani , MohammadReza Razvan

We study the phenomenological model of ensemble of two FitzHugh-Nagumo neuron-like elements with symmetric excitatory couplings. The main advantage of proposed model is the new approach to model of coupling which is implemented by smooth…

Dynamical Systems · Mathematics 2018-12-05 Alexander G. Korotkov , Alexey O. Kazakov , Tatiana A. Levanova , Grigory V. Osipov

The Hodgkin-Huxley equations constitute one of the more realistic neuronal models in literature and the most accepted one. It is well known that, depending on the value of the external stimuli current, it exhibits periodic solutions, both…

Dynamical Systems · Mathematics 2015-11-09 A. Balti , V. Lanza , M. A. Aziz-Alaou

This paper presents an overview of some techniques and concepts coming from dynamical system theory and used for the analysis of dynamical neural networks models. In a first section, we describe the dynamics of the neuron, starting from the…

Adaptation and Self-Organizing Systems · Physics 2011-11-09 B. Cessac , M. Samuelides

The behavior of neurons can be modeled by the FitzHugh-Nagumo oscillator model, consisting of two nonlinear differential equations, which simulates the behavior of nerve impulse conduction through the neuronal membrane. In this work, we…

Chaotic Dynamics · Physics 2015-04-29 Anderson Hoff , Juliana V. dos Santos , Cesar Manchein , Holokx A. Albuquerque

The FitzHugh-Nagumo equation, which was derived as a simplification of the Hodgkin-Huxley model for nerve impulse propagation, has been extensively studied as a paradigmatic activator-inhibitor system. We consider the version of this system…

Dynamical Systems · Mathematics 2018-03-15 Paul Cornwell , Christopher K. R. T. Jones

The FitzHugh-Nagumo equation, originally conceived in neuroscience during the 1960s, became a key model providing a simplified view of excitable neuron cell behavior. Its applicability, however, extends beyond neuroscience into fields like…

Pattern Formation and Solitons · Physics 2025-01-08 Daniel Cebrián-Lacasa , Pedro Parra-Rivas , Daniel Ruiz-Reynés , Lendert Gelens

The dynamics of a multiplex heterogeneous network of oscillators is studied. Two types of similar models based on the Hodgkin-Huxley formalism are used as the basic elements of the networks. The first type model demonstrates bursting…

Disordered Systems and Neural Networks · Physics 2021-06-03 Nataliya Stankevich

The dynamics of complex-valued fractional-order neuronal networks are investigated, focusing on stability, instability and Hopf bifurcations. Sufficient conditions for the asymptotic stability and instability of a steady state of the…

Dynamical Systems · Mathematics 2017-03-21 Eva Kaslik , Ileana Rodica Radulescu

Neuromorphic computing targets energy-efficient event-driven information processing by placing artificial spiking-neurons at its core. Artificial neuron devices and circuits have multiple operating modes and produce region-dependent…

Applied Physics · Physics 2026-01-06 Zhiwei Li , Shi-Li Zhang , Chenyu Wen

We discuss synchronization in networks of neuronal oscillators which are interconnected via diffusive coupling, i.e. linearly coupled via gap junctions. In particular, we present sufficient conditions for synchronization in these networks…

Pattern Formation and Solitons · Physics 2015-05-13 Erik Steur , Ivan Tyukin , Henk Nijmeijer

Hodgkin-Huxley equations as a monumental breakthrough in biological and physiological theory of the 20th century had been distilled into many simplified models to study, typically FitzHugh-Nagumo equations and Hindmarsh-Rose equations, but…

Analysis of PDEs · Mathematics 2026-05-11 Yuncheng You
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