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Text Simplification improves the readability of sentences through several rewriting transformations, such as lexical paraphrasing, deletion, and splitting. Current simplification systems are predominantly sequence-to-sequence models that…

Computation and Language · Computer Science 2021-04-16 Mounica Maddela , Fernando Alva-Manchego , Wei Xu

Protein-protein interactions (PPIs) are crucial in regulating numerous cellular functions, including signal transduction, transportation, and immune defense. As the accuracy of multi-chain protein complex structure prediction improves, the…

Biomolecules · Quantitative Biology 2024-02-07 Chenqing Hua , Connor Coley , Guy Wolf , Doina Precup , Shuangjia Zheng

Protein-protein interaction (PPI) networks, providing a comprehensive landscape of protein interacting patterns, enable us to explore biological processes and cellular components at multiple resolutions. For a biological process, a number…

Molecular Networks · Quantitative Biology 2016-04-13 Xiuli Ma , Guangyu Zhou , Jingjing Wang , Jian Peng , Jiawei Han

Sentence Simplification aims to rephrase complex sentences into simpler sentences while retaining original meaning. Large Language models (LLMs) have demonstrated the ability to perform a variety of natural language processing tasks.…

Computation and Language · Computer Science 2023-02-24 Yutao Feng , Jipeng Qiang , Yun Li , Yunhao Yuan , Yi Zhu

Drug-drug interaction (DDI) is a major cause of morbidity and mortality and a subject of intense scientific interest. Biomedical literature mining can aid DDI research by extracting evidence for large numbers of potential interactions from…

Machine Learning · Statistics 2015-05-19 Artemy Kolchinsky , Anália Lourenço , Heng-Yi Wu , Lang Li , Luis M. Rocha

Motivation: Protein-protein interactions (PPI) are critical to the function of proteins in both normal and diseased cells, and many critical protein functions are mediated by interactions.Knowledge of the nature of these interactions is…

Computation and Language · Computer Science 2022-01-10 Aparna Elangovan , Melissa Davis , Karin Verspoor

Sentence simplification aims to simplify the content and structure of complex sentences, and thus make them easier to interpret for human readers, and easier to process for downstream NLP applications. Recent advances in neural machine…

Computation and Language · Computer Science 2018-04-23 Tu Vu , Baotian Hu , Tsendsuren Munkhdalai , Hong Yu

Relation extraction is a fundamental problem in natural language processing. Most existing models are defined for relation extraction in the general domain. However, their performance on specific domains (e.g., biomedicine) is yet unclear.…

Computation and Language · Computer Science 2021-12-14 Yongkang Li

Protein-protein interactions (PPIs) are crucial in various biological processes and their study has significant implications for drug development and disease diagnosis. Existing deep learning methods suffer from significant performance…

Molecular Networks · Quantitative Biology 2023-05-16 Ziyuan Zhao , Peisheng Qian , Xulei Yang , Zeng Zeng , Cuntai Guan , Wai Leong Tam , Xiaoli Li

Protein-protein interaction extraction is the key precondition of the construction of protein knowledge network, and it is very important for the research in the biomedicine. This paper extracted directional protein-protein interaction from…

Computation and Language · Computer Science 2014-08-25 Peilei Liu , Ting Wang

Background: Protein-protein interaction (PPI) network analyses are highly valuable in deciphering and understanding the intricate organisation of cellular functions. Nevertheless, the majority of available protein-protein interaction…

Molecular Networks · Quantitative Biology 2015-01-08 Oussema Souiai , Fatma Guerfali , Slimane Ben Miled , Christine Brun , Alia Benkahla

Protein-protein interactions (PPIs) govern nearly all cellular processes, yet computational methods for identifying binding partners typically produce ranked predictions without mechanistic justification. This creates a fundamental barrier…

Quantitative Methods · Quantitative Biology 2026-05-22 Kingsley Yeon , Xuefeng Liu , Promit Ghosal

A systematic review identifies and collates various clinical studies and compares data elements and results in order to provide an evidence based answer for a particular clinical question. The process is manual and involves lot of time. A…

Information Retrieval · Computer Science 2016-06-22 Tanmay Basu , Shraman Kumar , Abhishek Kalyan , Priyanka Jayaswal , Pawan Goyal , Stephen Pettifer , Siddhartha R. Jonnalagadda

We provide a visualization model that targets the visualization of Protein-Protein Interactions(PPI) and combines it with a super view based on publications and methods to extract interactions. Although there are several existing tools, our…

Information Retrieval · Computer Science 2021-11-29 Melih Sozdinler

Biomedical Information Extraction is an exciting field at the crossroads of Natural Language Processing, Biology and Medicine. It encompasses a variety of different tasks that require application of state-of-the-art NLP techniques, such as…

Computation and Language · Computer Science 2017-05-17 Surag Nair

The prediction of protein interactions (CPIs) is crucial for the in-silico screening step in drug discovery. Recently, many end-to-end representation learning methods using deep neural networks have achieved significantly better performance…

Quantitative Methods · Quantitative Biology 2020-11-30 Jingtao Wang , Xi Li , Hua Zhang

Predicting protein-protein interactions (PPIs) by learning informative representations from amino acid sequences is a challenging yet important problem in biology. Although various deep learning models in Siamese architecture have been…

Machine Learning · Computer Science 2020-10-19 Kishan KC , Feng Cui , Anne Haake , Rui Li

Biological data are extremely diverse, complex but also quite sparse. The recent developments in deep learning methods are offering new possibilities for the analysis of complex data. However, it is easy to be get a deep learning model that…

Machine Learning · Computer Science 2019-01-21 Florian Richoux , Charlène Servantie , Cynthia Borès , Stéphane Téletchéa

The goal of text simplification (TS) is to transform difficult text into a version that is easier to understand and more broadly accessible to a wide variety of readers. In some domains, such as healthcare, fully automated approaches cannot…

Computation and Language · Computer Science 2020-10-22 Hoang Van , David Kauchak , Gondy Leroy

Complexes of physically interacting proteins are one of the fundamental functional units responsible for driving key biological mechanisms within the cell. Their identification is therefore necessary not only to understand complex formation…

Computational Engineering, Finance, and Science · Computer Science 2012-11-27 Sriganesh Srihari , Hon Wai Leong