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This work focuses on optimal controls of a class of stochastic SIS epidemic models under regime switching. By assuming that a decision maker can either influence the infectivity period or isolate infected individuals, our aim is to minimize…

Optimization and Control · Mathematics 2021-01-12 Ky Tran , George Yin

As global living standards improve and medical technology advances, many infectious diseases have been effectively controlled. However, certain diseases, such as the recent COVID-19 pandemic, continue to pose significant threats to public…

Numerical Analysis · Mathematics 2025-02-24 Ayesha Baig , Li Zhouxin

This is the second part of study on the optimal convergence rate of the explicit Euler discretization in time for the convection-diffusion equations [Appl. Math. Lett. \textbf{131} (2022) 108048] which focuses on high-dimensional…

Numerical Analysis · Mathematics 2022-05-13 Qifeng Zhang , Jiyuan Zhang , Zhi-zhong Sun

Delayed processes are ubiquitous throughout biology. These delays may arise through maturation processes or as the result of complex multi-step networks, and mathematical models with distributed delays are increasingly used to capture the…

Populations and Evolution · Quantitative Biology 2024-10-15 Tyler Cassidy

In this work we are interested in the modelling and control of opinion dynamics spreading on a time evolving network with scale-free asymptotic degree distribution. The mathematical model is formulated as a coupling of an opinion alignment…

Optimization and Control · Mathematics 2015-11-03 Giacomo Albi , Lorenzo Pareschi , Mattia Zanella

Optimal control of large particle systems with collective dynamics by few agents is a subject of high practical importance (e.g. in evacuation dynamics), but still limited mathematical basis. In particular the transition from discrete…

Optimization and Control · Mathematics 2016-10-06 Martin Burger , René Pinnau , Andreas Roth , Claudia Totzeck , Oliver Tse

Reliable and timely dengue predictions provide actionable lead time for targeted vector control and clinical preparedness, reducing preventable diseases and health-system costs in at-risk communities. Dengue forecasting often relies on…

Applications · Statistics 2025-12-01 Saman Hosseini , Lee W. Cohnstaedt , Caterina Scoglio

This work discloses an epidemiological mathematical model to predict an empirical treatment for dogs infected by Pseudomonas aeruginosa. This dangerous pathogen is one of the leading causes of multi-resistant infections and can be…

Populations and Evolution · Quantitative Biology 2024-01-17 Javier López-de-la-Cruz , María Pérez-Aranda , Ana Alcudia , Belén Begines , Tomás Caraballo , Eloísa Pajuelo , Pedro J. Ginel

It is recognized that social heterogeneities in terms of the contact distribution have a strong influence on the spread of infectious diseases. Nevertheless, few data are available on the group composition of social contacts, and their…

Optimization and Control · Mathematics 2023-06-09 Jonathan Franceschi , Andrea Medaglia , Mattia Zanella

This work addresses an optimal control problem on a dynamics governed by a nonlinear differential equation with a bistable time-periodic nonlinearity. This problem, relevant in population dynamics, models the strategy of replacing a…

Optimization and Control · Mathematics 2026-01-14 Grégoire Nadin , David Nahmani , Nicolas Vauchelet

In this work we introduce a new approach to Dynamical Monte Carlo methods to simulate markovian processes. We apply this approach to formulate and study an epidemic generalized SIRS model. The results are in excellent agreement with the…

Biological Physics · Physics 2007-05-23 O. E. Aiello , M. A. A. da Silva

In this paper, we study the dynamics of epidemic processes taking place in temporal and adaptive networks. Building on the activity-driven network model, we propose an adaptive model of epidemic processes, where the network topology…

Social and Information Networks · Computer Science 2018-02-27 Masaki Ogura , Victor M. Preciado , Naoki Masuda

Although dengue fever is an ancient disease that should have been eradicated since time ago, in Mexico as well as in other regions worldwide the cases of classic and hemorrhagic dengue continue to be reported presently. Since 2002 (and…

Populations and Evolution · Quantitative Biology 2016-01-28 Erick J. Lopez-Sanchez , Norma Y. Sanchez-Torres , Carlos Trenado , Juan M. Romero

Mosquitoes are vectors of many human diseases. In particular, Aedes \ae gypti (Linnaeus) is the main vector for Chikungunya, Dengue, and Zika viruses in Latin America and it represents a global threat. Public health policies that aim at…

Machine Learning · Statistics 2018-05-08 J. M. Scavuzzo , F. Trucco , M. Espinosa , C. B. Tauro , M. Abril , C. M. Scavuzzo , A. C. Frery

Li, Chen, Tai & E. (J. Machine Learning Research, 2018) have proposed a regularization of the forward-backward sweep iteration for solving the Pontryagin maximum principle in optimal control problems. The authors prove the global…

Numerical Analysis · Mathematics 2020-08-21 Xin Liu , Jason Frank

Infection by distinct Dengue virus serotypes and host immunity are intricately linked. In particular, certain levels of cross-reactive antibodies in the host may actually enhance infection severity leading to Dengue hemorrhagic fever (DHF).…

Populations and Evolution · Quantitative Biology 2019-12-19 Hayriye Gulbudak , Cameron J. Browne

In this paper, we consider the problem of optimizing the worst-case behavior of a partially observed system. All uncontrolled disturbances are modeled as finite-valued uncertain variables. Using the theory of cost distributions, we present…

Optimization and Control · Mathematics 2023-02-21 Aditya Dave , Nishanth Venkatesh , Andreas A. Malikopoulos

We study the effect of the streamline upwind/Petrov Galerkin (SUPG) stabilized finite element method on the discretization of optimal control problems governed by linear advection-diffusion equations. We compare two approaches for the…

Numerical Analysis · Mathematics 2024-11-18 S. Scott Collis , Matthias Heinkenschloss

Frequent emergence of communicable diseases has been a major concern worldwide. Lack of sufficient resources to mitigate the disease-burden makes the situation even more challenging for lower-income countries. Hence, strategy development…

Populations and Evolution · Quantitative Biology 2023-02-03 Biplab Maity , Swarnendu Banerjee , Abhishek Senapati , Joydev Chattopadhyay

We consider a controlled reaction-diffusion equation, motivated by a pest eradication problem. Our goal is to derive a simpler model, describing the controlled evolution of a contaminated set. In this direction, the first part of the paper…

Optimization and Control · Mathematics 2021-08-24 Alberto Bressan , Maria Teresa Chiri , Najmeh Salehi
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