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Related papers: Dendritic Cells for Real-Time Anomaly Detection

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Distributed system as e.g. artificial immune systems, complex adaptive systems, or multi-agent systems are widely used in Computer Science, e.g. for network security, optimisations, or simulations. In these systems, small entities move…

Multiagent Systems · Computer Science 2008-05-14 Michael Hilker

We study the emergence of the collective spatio-temporal macroscopic properties of the immune system, by representing individually the elementary interactions between its microscopic components (antibodies, antigens, cytokines). The results…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Yoram Louzoun , Sorin Solomon , Henri Atlan , Irun. R. Cohen

Anomaly detection is to identify samples that do not conform to the distribution of the normal data. Due to the unavailability of anomalous data, training a supervised deep neural network is a cumbersome task. As such, unsupervised methods…

Computer Vision and Pattern Recognition · Computer Science 2022-07-05 Vahid Reza Khazaie , Anthony Wong , John Taylor Jewell , Yalda Mohsenzadeh

Many dynamical systems of interest are nonlinear, with examples in turbulence, epidemiology, neuroscience, and finance, making them difficult to control using linear approaches. Model predictive control (MPC) is a powerful model-based…

Optimization and Control · Mathematics 2021-08-31 Urban Fasel , Eurika Kaiser , J. Nathan Kutz , Bingni W. Brunton , Steven L. Brunton

The Clock Drawing Test (CDT) is a rapid, inexpensive, and popular neuropsychological screening tool for cognitive conditions. The Digital Clock Drawing Test (dCDT) uses novel software to analyze data from a digitizing ballpoint pen that…

Machine Learning · Statistics 2016-06-24 William Souillard-Mandar , Randall Davis , Cynthia Rudin , Rhoda Au , Dana Penney

Deep neural networks (DNNs) have demonstrated exceptional success across various tasks, underscoring the need to evaluate the robustness of advanced DNNs. However, traditional methods using stickers as physical perturbations to deceive…

Computer Vision and Pattern Recognition · Computer Science 2023-05-24 Chengyin Hu , Weiwen Shi

The goal is to develop a novel approach for cardiac disease prediction and diagnosis using intelligent agents. Initially the symptoms are preprocessed using filter and wrapper based agents. The filter removes the missing or irrelevant…

Multiagent Systems · Computer Science 2010-09-28 Murugesan Kuttikrishnan

We envision "AI scientists" as systems capable of skeptical learning and reasoning that empower biomedical research through collaborative agents that integrate AI models and biomedical tools with experimental platforms. Rather than taking…

Understanding the morphological changes of primary neuronal cells induced by chemical compounds is essential for drug discovery. Using the data from a single high-throughput imaging assay, a classification model for predicting the…

Image and Video Processing · Electrical Eng. & Systems 2019-09-02 Andrey Kormilitzin , Xinyu Yang , William H. Stone , Caroline Woffindale , Francesca Nicholls , Elena Ribe , Alejo Nevado-Holgado , Noel Buckley

Top-down feedback in cortex is critical for guiding sensory processing, which has prominently been formalized in the theory of hierarchical predictive coding (hPC). However, experimental evidence for error units, which are central to the…

Neurons and Cognition · Quantitative Biology 2022-11-23 Fabian A. Mikulasch , Lucas Rudelt , Michael Wibral , Viola Priesemann

We develop an online data-enabled predictive (ODeePC) control method for optimal control of unknown systems, building on the recently proposed DeePC [1]. Our proposed ODeePC method leverages a primal-dual algorithm with real-time…

Optimization and Control · Mathematics 2020-11-20 Stefanos Baros , Chin-Yao Chang , Gabriel E. Colon-Reyes , Andrey Bernstein

Dendrites are crucial structures for computation of an individual neuron. It has been shown that the dynamics of a biological neuron with dendrites can be approximated by artificial neural networks (ANN) with deep structure. However, it…

Neurons and Cognition · Quantitative Biology 2023-05-23 Jingyang Ma , Songting Li , Douglas Zhou

Cells coexist together in colonies or as tissues. Their behaviour is controlled by an interplay between intercellular forces and biochemical regulation. We develop a simple model of the cell cycle, the fundamental regulatory network…

Biological Physics · Physics 2021-08-04 Jintao Li , Simon K. Schnyder , Matthew S. Turner , Ryoichi Yamamoto

Cybergenetic gene expression control in bacteria enables applications in engineering biology, drug development, and biomanufacturing. AI-based controllers offer new possibilities for real-time, single-cell-level regulation but typically…

Systems and Control · Electrical Eng. & Systems 2026-05-13 Liam Perreault , Idris Kempf , Kirill Sechkar , Jean-Baptiste Lugagne , Antonis Papachristodoulou

The coordination of the immune system and its components is essential for the body to maintain a healthy status. Recent clinical studies show that breast cancer patients with high Dendritic cell clustering in tumour draining lymph nodes…

Cell Behavior · Quantitative Biology 2026-04-21 Domenic P. J. Germano , Federico Frascoli , Robyn P. Araujo , Peter P. Lee , Peter S. Kim

Conventional electronics is founded on a paradigm where shaping perfect electrical elements is done at the fabrication plant, so as to make devices and systems identical, "eternally immutable". In nature, morphogenic evolutions are observed…

Cell movement, for example during embryogenesis or tumor metastasis, is a complex dynamical process resulting from an intricate interplay of multiple components of the cellular migration machinery. At first sight, the paths of migrating…

Cell Behavior · Quantitative Biology 2009-04-17 Peter Dieterich , Rainer Klages , Roland Preuss , Albrecht Schwab

Computers are deterministic dynamical systems (CHAOS 19:033124, 2009). Among other things, that implies that one should be able to use deterministic forecast rules to predict their behavior. That statement is sometimes-but not always-true.…

Chaotic Dynamics · Physics 2013-05-24 Joshua Garland , Ryan James , Elizabeth Bradley

We consider the problem of detecting anomalies among a given set of processes using their noisy binary sensor measurements. The noiseless sensor measurement corresponding to a normal process is 0, and the measurement is 1 if the process is…

Signal Processing · Electrical Eng. & Systems 2020-06-02 Geethu Joseph , M. Cenk Gursoy , Pramod K. Varshney

Circulating tumor cells (CTCs) are cancer cells found in the bloodstream that serve as biomarkers for early cancer detection, prognostication, and disease monitoring. However, CTC detection remains challenging due to low cell abundance and…