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Reversibility, weak reversibility and deficiency, detailed and complex balancing are generally not "encoded" in the kinetic differential equations but they are realization properties that may imply local or even global asymptotic stability…

Molecular Networks · Quantitative Biology 2011-05-11 Gabor Szederkenyi , Katalin M. Hangos

The characterization of the notions of complex and detailed balancing for mass action kinetics chemical reaction networks is revisited from the perspective of algebraic graph theory, in particular Kirchhoff's Matrix Tree theorem for…

Dynamical Systems · Mathematics 2015-03-09 Arjan van der Schaft , Shodhan Rao , Bayu Jayawardhana

The principle of detailed balance (DB) states that every kinetic transition in a system with many micro-states, $\mu$, is balanced, on average, with the opposite transition, $\mu_i\leftrightharpoons\mu_j$. Since its introduction by…

Soft Condensed Matter · Physics 2022-12-29 Xulai Sun , Yinqiao Wang , Yujie Wang , Raphael Blumenfeld , Jie Zhang

A complex balanced kinetic system is absolutely complex balanced (ACB) if every positive equilibrium is complex balanced. Two results on absolute complex balancing were foundational for modern chemical reaction network theory (CRNT): in…

Dynamical Systems · Mathematics 2021-12-28 Editha C. Jose , Eduardo R. Mendoza , Dylan Antonio SJ. Talabis

Very often, models in biology, chemistry, physics, and engineering are systems of polynomial or power-law ordinary differential equations, arising from a reaction network. Such dynamical systems can be generated by many different reaction…

Dynamical Systems · Mathematics 2020-01-01 Gheorghe Craciun , Jiaxin Jin , Polly Y. Yu

We develop a general approach to setting up and studying classes of quantum dynamical systems close to and structurally similar to systems having specified properties, in particular detailed balance. This is done in terms of transport plans…

Quantum Physics · Physics 2025-05-13 Rocco Duvenhage , Samuel Skosana , Machiel Snyman

We further clarify the relation between detailed-balanced and complex-balanced equilibria of reversible chemical reaction networks. Our results hold for arbitrary kinetics and also for boundary equilibria. Detailed balance, complex balance,…

Dynamical Systems · Mathematics 2020-09-29 Stefan Müller , Badal Joshi

The principle of detailed balance states that in equilibrium each elementary process is equilibrated by its reverse process. For many real physico-chemical complex systems (e.g. homogeneous combustion, heterogeneous catalytic oxidation,…

Statistical Mechanics · Physics 2011-08-24 A. N. Gorban , G. S. Yablonsky

We consider various modeling levels for spatially homogeneous chemical reaction systems, namely the chemical master equation, the chemical Langevin dynamics, and the reaction-rate equation. Throughout we restrict our study to the case where…

Analysis of PDEs · Mathematics 2020-12-02 Jan Maas , Alexander Mielke

Mass action type deterministic kinetic models of ion channels are usually constructed in such a way as to obey the principle of detailed balance (or, microscopic reversibility) for two reasons: first, the authors aspire to have models…

Molecular Networks · Quantitative Biology 2011-09-21 I. Nagy , J. Tóth

Transient bonds between fast linkers and slower particles are widespread in physical and biological systems. In spite of their diverse structure and function, a commonality is that the linkers diffuse on timescales much faster compared to…

Soft Condensed Matter · Physics 2023-06-06 Sophie Marbach , Christopher E. Miles

The detailed balance property is a fundamental property that must be satisfied in all the macroscopic systems with a well defined temperature at each point. On the other hand, many biochemical networks work in non-equilibrium conditions and…

Classical Analysis and ODEs · Mathematics 2025-02-10 E. Franco , J. J. L. Velázquez

The general theory of a complex system of nonlinear chemical reactions is a primary language of chemistry that includes chemical engineering and cellular biochemistry. Its significance as an analytical framework, however, has not been fully…

Chemical Physics · Physics 2025-10-21 Liu Hong , Hong Qian

Living systems are typically characterized by irreversible processes. A condition equivalent to the reversibility is the detailed balance, whose absence is an obstacle for analytically solving ecological models. We revisit a promising model…

Statistical Mechanics · Physics 2012-11-20 Jacopo Grilli , Sandro Azaele , Jayanth R. Banavar , Amos Maritan

Mass action systems capture chemical reaction networks in homogeneous and dilute solutions. We suggest a notion of generalized mass action systems that admits arbitrary nonnegative power-law rate functions and serves as a more realistic…

Dynamical Systems · Mathematics 2013-08-15 Stefan Müller , Georg Regensburger

We propose a formal extension of thermodynamics and kinetic theories to a larger class of entropy functionals. Kinetic equations associated to Boltzmann, Fermi, Bose and Tsallis entropies are recovered as a special case. This formalism…

Statistical Mechanics · Physics 2015-06-24 Pierre-Henri Chavanis

The standard assumptions that underlie many conceptual and quantitative frameworks do not hold for many complex physical, biological, and social systems. Complex systems science clarifies when and why such assumptions fail and provides…

Physics and Society · Physics 2020-11-11 Alexander F. Siegenfeld , Yaneer Bar-Yam

The graph-related symmetries of a reaction network give rise to certain special equilibria (such as complex balanced equilibria) in deterministic models of dynamics of the reaction network. Correspondingly, in the stochastic setting, when…

Probability · Mathematics 2018-05-21 Daniele Cappelletti , Badal Joshi

It is well known that, for mass-action systems, complex-balanced equilibria are asymptotically stable. For generalized mass-action systems, even if there exists a unique complex-balanced equilibrium (in every stoichiometric class and for…

Dynamical Systems · Mathematics 2022-09-14 Balazs Boros , Stefan Müller , Georg Regensburger

We develop a general framework for the discussion of detailed balance and analyse its microscopic background. We find that there should be two additions to the well-known $T$- or $PT$-invariance of the microscopic laws of motion: 1.…

Statistical Mechanics · Physics 2014-10-09 A. N. Gorban
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