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The segregation of plasmids in a bacterial population is investigated. Hereby, a dynamical model is formulated in terms of a size-structured population using a hyperbolic partial differential equation incorporating non-local terms (the…

Populations and Evolution · Quantitative Biology 2017-01-13 Johannes Müller , Karin Münch , Bendix Koopmann , Eva Stadler , Louisa Roselius , Dieter Jahn , Richard Münch

We study the effect of discreteness on various models for patterning in bacterial colonies. In a bacterial colony with branching pattern, there are discrete entities - bacteria - which are only two orders of magnitude smaller than the…

Disordered Systems and Neural Networks · Physics 2007-05-23 Inon Cohen , Ido Golding , Yonathan Kozlovsky , Eshel Ben-Jacob

One of the most interesting phenomena in the soft-matter realm consists in the spontaneous formation of super-molecular structures (microphases) in condition of thermodynamic equilibrium. A simple mechanism responsible for this…

Soft Condensed Matter · Physics 2017-08-23 A. Imperio , D. Pini , L. Reatto

We study numerically and analytically the dynamics of a sedimenting suspension of active, reproducing particles, such as growing bacteria in a gravitational field. In steady state we find a non-equilibrium phase transition between a…

Statistical Mechanics · Physics 2009-11-13 C. Barrett-Freeman , M. R. Evans , D. Marenduzzo , W. C. K. Poon

We explore phase separation and kinetic arrest in a model active colloidal system consisting of self-propelled, hard-core particles with nonconvex shapes. The passive limit of the model, namely cross-shaped particles on a square lattice,…

Soft Condensed Matter · Physics 2020-05-11 Carl Merrigan , Kabir Ramola , Rakesh Chatterjee , Nimrod Segall , Yair Shokef , Bulbul Chakraborty

We investigate the structure and stability of the steady states for a bacterial colony model with density-suppressed motility. We treat the growth rate of bacteria as a bifurcation parameter to explore the local and global structure of the…

Analysis of PDEs · Mathematics 2020-05-15 Manjun Ma , Peng Xia , Qifeng Zhang , Matti Vuorinen

Various bacterial strains (e.g. strains belonging to the genera Bacillus, Paenibacillus, Serratia and Salmonella) exhibit colonial branching patterns during growth on poor semi-solid substrates. These patterns reflect the bacterial…

Condensed Matter · Physics 2009-10-31 Yonathan Kozlovsky , Inon Cohen , Ido Golding , Eshel Ben-Jacob

Centrifugation of biological matter in density gradient solutions is a standard method for separating cell types or components. It is also used to separate red blood cells (RBCs) by age, as they lose water and become denser over their…

Soft Condensed Matter · Physics 2026-02-09 Felix Maurer , Camila Romero , Nikolas Lerch , Thomas John , Lars Kaestner , Christian Wagner , Alexis Darras

We study the steady state resulting from instabilities in crystals driven through a dissipative medium, for instance, a colloidal crystal which is steadily sedimenting through a viscous fluid. The problem involves two coupled fields, the…

Statistical Mechanics · Physics 2009-10-31 Rangan Lahiri , Mustansir Barma , Sriram Ramaswamy

The trajectories of microswimmers moving in narrow channels of widths comparable to their sizes are significantly altered when they encounter another microswimmer moving in the opposite direction. The consequence of these encounters is a…

The influence of size differences, shape, mass and persistent motion on phase separation in binary mixtures has been intensively studied. Here we focus on the exclusive role of diffusivity differences in binary mixtures of equal-sized…

Soft Condensed Matter · Physics 2016-03-04 Simon N. Weber , Christoph A. Weber , Erwin Frey

Gradient-driven diffusion in crowded, multicomponent mixtures is a topic of high interest because of its role in biological processes such as transport in cell membranes. In partially phase-separated solutions, gradient-driven diffusion…

Soft Condensed Matter · Physics 2017-02-15 Prithviraj Nandigrami , Brandy Grove , Andrew Konya , Robin L. B. Selinger

We examine a non-reciprocally coupled dynamical model of a mixture of two diffusing species. We demonstrate that nonreciprocity, which is encoded in the model via antagonistic cross diffusivities, provides a generic mechanism for the…

Soft Condensed Matter · Physics 2020-08-21 Zhihong You , Aparna Baskaran , M. Cristina Marchetti

Quenched or frozen-in structural disorder is ubiquitous in real experimental systems. Much of the progress is achieved in understanding the phase separation of such systems using the diffusion-driven coarsening in Ising model with quenched…

Soft Condensed Matter · Physics 2023-08-15 Rounak Bhattacharyya , Bhaskar Sen Gupta

Dense suspensions of swimming bacteria are known to exhibit collective behaviour arising from the interplay of steric and hydrodynamic interactions. Unconfined suspensions exhibit transient, recurring vortices and jets, whereas those…

Biological Physics · Physics 2016-07-04 Hugo Wioland , Enkeleida Lushi , Raymond E. Goldstein

Microphase separation is common in active biological systems as exemplified by the separation of RNA and DNA-rich phases in the cell nucleus driven by the transcriptional activity of polymerase enzymes acting similarly to amphiphiles in a…

Soft Condensed Matter · Physics 2025-07-22 Rakesh Chatterjee , Hui-Shun Kuan , Frank Julicher , Vasily Zaburdaev

Spontaneous phase separation, or demixing, is important in biological phenomena such as cell sorting. In particle-based models, an open question is whether differences in diffusivity can drive such demixing. While…

Soft Condensed Matter · Physics 2023-07-10 Erin McCarthy , Ojan Damavandi , Raj Kumar Manna , M. Lisa Manning

Phase separation can drive spatial organization of multicomponent mixtures. For instance in developing animal embryos, effective phase separation descriptions have been used to account for the spatial organization of different tissue types.…

Soft Condensed Matter · Physics 2023-01-18 Simon Gsell , Matthias Merkel

We study pattern formation in gels undergoing simultaneous phase separation and orientational ordering. A 2D numerical simulation is performed using a minimal model of nonlinear elasticity with density-anisotropy coupling. For strong…

Soft Condensed Matter · Physics 2009-11-07 Nariya Uchida

Non-equilibrium phase separating systems with reactions can break time-reversal symmetry (TRS) in two distinct ways. Firstly, the conservative and non-conservative sectors of the dynamics can be governed by incompatible free energies; when…

Soft Condensed Matter · Physics 2021-05-31 Yuting I. Li , Michael E. Cates