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We present a novel microfluidic method to produce quasi-monodisperse bubbles with diameters from tens to very few microns. A gaseous rivulet flows over the shallow groove printed on a T-junction exit channel. The triple contact line…

Fluid Dynamics · Physics 2025-04-04 A. Rubio , S. Rodríguez-Aparicio , J. M. Montanero , M. G. Cabezas

Droplet microfluidics, in which micro-droplets serve as individual reactors, has enabled a wide range of high-throughput biochemical processes. Unlike solid wells typically used in current biochemical assays, droplets are subject to…

Soft Condensed Matter · Physics 2022-06-03 Ya Gai , Andrea Montessori , Sauro Succi , Sindy K. Y. Tang

Reliable measurement of droplet/bubble size and velocity distributions in dense flows is desired in a variety of research fields, both for laboratory and industrial use. A new type of single-mode monofiber optical probe manufactured by A2…

Applied Physics · Physics 2021-10-26 Mathieu Alonzo , Anthony Lefebvre , Zhujun Huang , Stéphane Gluck , Alain Cartellier

Microfluidics is an established multidisciplinary research domain with widespread applications in the fields of medicine, biotechnology and engineering. Conventional production methods of microfluidic chips have been limited to planar…

The mechanical properties of biological fluids can serve as early indicators of disease, offering valuable insights into complex physiological and pathological processes. However, the existing technologies can hardly support high throughput…

Optics · Physics 2025-09-18 Zhonghao Li , Zhihan Cai , Chaoyang Gong

This paper describes the techniques and physical parameters used to produce stable centimetric water drops in microgravity, and to study single cavitation bubbles inside such drops (Parabolic Flight Campaigns, European Space Agency ESA).…

Fluid Dynamics · Physics 2010-10-22 Philippe Kobel , Danail Obreschkow , Aurèle de Bosset , Nicolas Dorsaz , M. Farhat

We demonstrate a compact piezoelectric-driven micropipette launcher for localized in-vacuum delivery of nano- and microparticles into optical traps. The launcher has been integrated into multiple optical trapping setups, including a…

We reveal an unreported physical mechanism that enables the pre-concentration, sorting and characterization of charged polystyrene nanobeads and liposomes dispersed in a continuous flow within a straight micron-sized channel. Initially, a…

Manipulation of micro/nano particles has been well studied and demonstrated by optical, electromagnetic, and acoustic approaches, or their combinations. Manipulation of internal structure of droplet/particle is rarely explored and remains…

Introducing controlled fluid motion inside a droplet turns out to be of outstanding scientific importance. In this work, we suggest a new method of flow manipulation inside a sessile droplet by simply deploying a static charge produced by…

In this study, we analyze the various arrangements that droplets can form within dispersed buoyant emulsions, which we refer to as the study of microstructure. To this end, we have developed a novel algorithm that effectively prevents…

Fluid Dynamics · Physics 2024-07-11 Nicolas Fintzi , Jean-Lou Pierson , Stéphane Popinet

The analysis of nano-and microparticle suspensions with micro systems affords improved space-time yields, selectivity, reaction residence times and conversions capabilities. These capabilities are of primary importance in various fields of…

Instrumentation and Detectors · Physics 2022-01-24 F. Onofri , Isaac Rodríguez-Ruiz , Fabrice Lamadie , Fabrice Onofri

Controlling fluid droplets efficiently in the microscale is of great interest both from a basic science and a technology perspective. We have designed and developed a general-purpose, highly scalable microfluidic control strategy through a…

Fluid Dynamics · Physics 2013-10-15 Georgios Katsikis , Manu Prakash

Precise manipulation of fluids and objects on the micro scale is seldom a simple task, but nevertheless crucial for many applications in life sciences and chemical engineering. We present a microfluidic chip fabricated in silicon-glass,…

Microcapsules allow for the controlled containment, transport, and release of cargoes ranging from pharmaceuticals to fragrances. Given the interest from a variety of industries in microcapsules and other core-shell structures, a multitude…

Soft Condensed Matter · Physics 2021-08-04 Steven Dang , John Brady , Ryle Rel , Sreenidhi Surineni , Conor O'Shaughnessy , Ryan McGorty

We present a versatile setup for investigating the nanofluidic behavior of nanoparticles as a function of the gap distance between two confining surfaces. The setup is designed as an open system which operates with small amounts of…

Soft Condensed Matter · Physics 2017-01-17 Stefan Fringes , Felix Holzner , Armin W. Knoll

Effective mixing is essential for biochemical reactions. In droplet-based microfluidics, immediate mixing of substances upon contact in the droplet formation stage can greatly enhance the uniformity of chemical reactions. Furthermore, it…

Micropumps are one of the most important parts of a microfluidic system. In particular, for biomedical applications such as Lab-on-Chip systems, micropumps are used to transport and manipulate test fluids in a controlled manner. In this…

Fluid Dynamics · Physics 2021-07-20 Sumana Bhattacharjee

Nanocarriers are nanosized materials commonly used for targeted-oriented delivery of active compounds, including antimicrobials and small-molecular drugs. They equally represent fundamental and engineering challenges since sophisticated…

Soft Condensed Matter · Physics 2021-01-19 François Sicard , Jhoan Toro-Mendoza

We present a microfluidic platform for two-dimensional manipulation of water droplets immersed in bulk oil-based ferrofluid. Although non-magnetic, the droplets are exclusively controlled by magnetic fields, without any pressure-driven…

Fluid Dynamics · Physics 2017-12-05 Georgios Katsikis , Alexandre Breant , Anatoly Rinberg , Manu Prakash