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A phylogenetic variety is an algebraic variety parameterized by a statistical model of the evolution of biological sequences along a tree. Understanding this variety is an important problem in the area of algebraic statistics with…

Populations and Evolution · Quantitative Biology 2024-05-22 Luis David Garcia Puente , Marina Garrote-López , Elima Shehu

Phylogenetic invariants are certain polynomials in the joint probability distribution of a Markov model on a phylogenetic tree. Such polynomials are of theoretical interest in the field of algebraic statistics and they are also of practical…

Populations and Evolution · Quantitative Biology 2008-01-21 Nicholas Eriksson

In this paper we investigate properties of algebraic varieties representing group-based phylogenetic models. We propose a method of generating many phylogenetic invariants. We prove that we obtain all invariants for any tree for the binary…

Algebraic Geometry · Mathematics 2012-07-30 Maria Donten-Bury , Mateusz Michalek

In the last decade, some algebraic tools have been successfully applied to phylogenetic reconstruction. These tools are mainly based on the knowledge of equations describing algebraic varieties associated to phylogenetic trees evolving…

Populations and Evolution · Quantitative Biology 2025-07-04 Marta Casanellas , Jesús Fernández-Sánchez

Statistical models of evolution are algebraic varieties in the space of joint probability distributions on the leaf colorations of a phylogenetic tree. The phylogenetic invariants of a model are the polynomials which vanish on the variety.…

Populations and Evolution · Quantitative Biology 2007-05-23 Bernd Sturmfels , Seth Sullivant

We introduce new methods for phylogenetic tree quartet construction by using machine learning to optimize the power of phylogenetic invariants. Phylogenetic invariants are polynomials in the joint probabilities which vanish under a model of…

Populations and Evolution · Quantitative Biology 2007-05-23 Nicholas Eriksson , Yuan Yao

Phylogenetic networks provide a means of describing the evolutionary history of sets of species believed to have undergone hybridization or gene flow during their evolution. The mutation process for a set of such species can be modeled as a…

Populations and Evolution · Quantitative Biology 2022-11-23 Travis Barton , Elizabeth Gross , Colby Long , Joseph Rusinko

We introduce the package PhylogeneticTrees for Macaulay2 which allows users to compute phylogenetic invariants for group-based tree models. We provide some background information on phylogenetic algebraic geometry and show how the package…

Populations and Evolution · Quantitative Biology 2021-01-27 Hector Baños , Nathaniel Bushek , Ruth Davidson , Elizabeth Gross , Pamela E. Harris , Robert Krone , Colby Long , Allen Stewart , Robert Walker

The general Markov model of the evolution of biological sequences along a tree leads to a parameterization of an algebraic variety. Understanding this variety and the polynomials, called phylogenetic invariants, which vanish on it, is a…

Algebraic Geometry · Mathematics 2007-06-13 Elizabeth S. Allman , John A. Rhodes

We prove identifiability of the tree parameters of the 3-class Jukes-Cantor mixture model. The proof uses ideas from algebraic statistics, in particular: finding phylogenetic invariants that separate the varieties associated to different…

Populations and Evolution · Quantitative Biology 2014-08-12 Colby Long , Seth Sullivant

The reconstruction of phylogenetic trees from molecular sequence data relies on modelling site substitutions by a Markov process, or a mixture of such processes. In general, allowing mixed processes can result in different tree topologies…

Populations and Evolution · Quantitative Biology 2016-09-07 Marta Casanellas , Mike Steel

The need for structures capable of accommodating complex evolutionary signals such as those found in, for example, wheat has fueled research into phylogenetic networks. Such structures generalize the standard phylogenetic tree model by also…

Combinatorics · Mathematics 2015-11-30 Philippe Gambette , Katharina T. Huber , Guillaume E. Scholz

The algebraic properties of flattenings and subflattenings provide direct methods for identifying edges in the true phylogeny -- and by extension the complete tree -- using pattern counts from a sequence alignment. The relatively small…

Populations and Evolution · Quantitative Biology 2022-05-06 Joshua Stevenson , Barbara Holland , Michael Charleston , Jeremy Sumner

The selection of the most suitable evolutionary model to analyze the given molecular data is usually left to biologist's choice. In his famous book, J Felsenstein suggested that certain linear equations satisfied by the expected…

Populations and Evolution · Quantitative Biology 2012-11-20 Marta Casanellas , Jesus Fernandez-Sanchez , Anna Kedzierska

Modelling the substitution of nucleotides along a phylogenetic tree is usually done by a hidden Markov process. This allows to define a distribution of characters at the leaves of the trees and one might be able to obtain polynomial…

Populations and Evolution · Quantitative Biology 2020-10-12 Marta Casanellas , Jesús Fernández-Sánchez , Marina Garrote-López

Null models of binary phylogenetic trees are useful for testing hypotheses on real world phylogenies. In this paper we consider phylogenies as binary trees without edge lengths together with a sampling measure and encode them as algebraic…

Probability · Mathematics 2020-06-17 Josué Nussbaumer , Anita Winter

Changing base composition during the evolution of biological sequences can mislead some of the phylogenetic inference techniques in current use. However, detecting whether such a process has occurred may be difficult, since convergent…

Populations and Evolution · Quantitative Biology 2007-05-23 Elizabeth S. Allman , John A. Rhodes

Phylogenetic invariants are equations that vanish on algebraic varieties associated with Markov processes that model molecular substitutions on phylogenetic trees. For practical applications, it is essential to understand these equations…

Populations and Evolution · Quantitative Biology 2025-05-28 Marta Casanellas , Jennifer Garbett , Roser Homs , Annachiara Korchmaros , Niharika Chakrabarty Paul

Identifiability of phylogenetic models is a necessary condition to ensure that the model parameters can be uniquely determined from data. Mixture models are phylogenetic models where the probability distributions in the model are convex…

Populations and Evolution · Quantitative Biology 2025-08-11 Bryson Kagy , Seth Sullivant

We apply the theory of markov random fields on trees to derive a phase transition in the number of samples needed in order to reconstruct phylogenies. We consider the Cavender-Farris-Neyman model of evolution on trees, where all the inner…

Probability · Mathematics 2007-05-23 Elchanan Mossel
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