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Clinical research often focuses on complex traits in which many variables play a role in mechanisms driving, or curing, diseases. Clinical prediction is hard when data is high-dimensional, but additional information, like domain knowledge…

Methodology · Statistics 2020-05-21 Mirrelijn M. van Nee , Lodewyk F. A. Wessels , Mark A. van de Wiel

We consider high-dimensional multiclass classification by sparse multinomial logistic regression. Unlike binary classification, in the multiclass setup one can think about an entire spectrum of possible notions of sparsity associated with…

Statistics Theory · Mathematics 2023-01-18 Tomer Levy , Felix Abramovich

For many high-dimensional studies, additional information on the variables, like (genomic) annotation or external p-values, is available. In the context of binary and continuous prediction, we develop a method for adaptive group-regularized…

In this paper, we consider the joint task of simultaneously optimizing (i) the weights of a deep neural network, (ii) the number of neurons for each hidden layer, and (iii) the subset of active input features (i.e., feature selection).…

Machine Learning · Statistics 2017-02-14 Simone Scardapane , Danilo Comminiello , Amir Hussain , Aurelio Uncini

Motivated by recent work on stochastic gradient descent methods, we develop two stochastic variants of greedy algorithms for possibly non-convex optimization problems with sparsity constraints. We prove linear convergence in expectation to…

Numerical Analysis · Mathematics 2014-07-02 Nam Nguyen , Deanna Needell , Tina Woolf

We consider the problem of multivariate regression in a setting where the relevant predictors could be shared among different responses. We propose an algorithm which decomposes the coefficient matrix into the product of a long matrix and a…

Machine Learning · Statistics 2016-03-02 Milad Kharratzadeh , Mark Coates

This paper considers generalized linear models using rule-based features, also referred to as rule ensembles, for regression and probabilistic classification. Rules facilitate model interpretation while also capturing nonlinear dependences…

Machine Learning · Computer Science 2019-06-06 Dennis Wei , Sanjeeb Dash , Tian Gao , Oktay Günlük

This paper considers the problem of networks reconstruction from heterogeneous data using a Gaussian Graphical Mixture Model (GGMM). It is well known that parameter estimation in this context is challenging due to large numbers of variables…

Machine Learning · Statistics 2013-10-08 Anani Lotsi , Ernst Wit

Imposition of a lasso penalty shrinks parameter estimates toward zero and performs continuous model selection. Lasso penalized regression is capable of handling linear regression problems where the number of predictors far exceeds the…

Applications · Statistics 2008-12-18 Tong Tong Wu , Kenneth Lange

Penalized least squares estimation is a popular technique in high-dimensional statistics. It includes such methods as the LASSO, the group LASSO, and the nuclear norm penalized least squares. The existing theory of these methods is not…

Statistics Theory · Mathematics 2017-07-10 Pierre C. Bellec , Guillaume Lecué , Alexandre B. Tsybakov

We study a norm for structured sparsity which leads to sparse linear predictors whose supports are unions of prede ned overlapping groups of variables. We call the obtained formulation latent group Lasso, since it is based on applying the…

Machine Learning · Statistics 2011-10-05 Guillaume Obozinski , Laurent Jacob , Jean-Philippe Vert

This paper develops a unified nonconvex optimization framework for the design of group-sparse feedback controllers in infinite-horizon linear-quadratic (LQ) problems. We address two prominent extensions of the classical LQ problem: the…

Optimization and Control · Mathematics 2025-08-06 Lechen Feng , Xun Li , Yuan-Hua Ni

Decision trees usefully represent sparse, high dimensional and noisy data. Having learned a function from this data, we may want to thereafter integrate the function into a larger decision-making problem, e.g., for picking the best chemical…

Optimization and Control · Mathematics 2019-09-26 Miten Mistry , Dimitrios Letsios , Gerhard Krennrich , Robert M. Lee , Ruth Misener

Optimization problems with convex quadratic cost and polyhedral constraints are ubiquitous in signal processing, automatic control and decision-making. We consider here an enlarged problem class that allows to encode logical conditions and…

Optimization and Control · Mathematics 2026-04-09 Alberto De Marchi

In this paper, we propose a double iteratively reweighted algorithm to solve nonconvex and nonsmooth optimization problems, where both the objectives and constraint functions are formulated by concave compositions to promote group-sparse…

Optimization and Control · Mathematics 2025-11-25 Wanqin Nie , Kai Tu , Minglu Ye , Shuqin Sun

Beta regression is commonly employed when the outcome variable is a proportion. Since its conception, the approach has been widely used in applications spanning various scientific fields. A series of extensions have been proposed over time,…

Methodology · Statistics 2025-07-29 Niloofar Ramezani , Martin Slawski

When faced with a supervised learning problem, we hope to have rich enough data to build a model that predicts future instances well. However, in practice, problems can exhibit predictive heterogeneity: most instances might be relatively…

Machine Learning · Statistics 2016-08-02 Rhiannon V. Rose , Daniel J. Lizotte

We propose generalized additive partial linear models for complex data which allow one to capture nonlinear patterns of some covariates, in the presence of linear components. The proposed method improves estimation efficiency and increases…

Statistics Theory · Mathematics 2014-05-26 Li Wang , Lan Xue , Annie Qu , Hua Liang

This paper is concerned with solving nonconvex learning problems with folded concave penalty. Despite that their global solutions entail desirable statistical properties, they lack optimization techniques that guarantee global optimality in…

Statistics Theory · Mathematics 2016-03-25 Hongcheng Liu , Tao Yao , Runze Li

High-dimensional sparse modeling via regularization provides a powerful tool for analyzing large-scale data sets and obtaining meaningful, interpretable models. The use of nonconvex penalty functions shows advantage in selecting important…

Methodology · Statistics 2016-05-12 Zemin Zheng , Yingying Fan , Jinchi Lv