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We investigate the evolutionary dynamics of a finite population of sequences adapting to NK fitness landscapes. We find that, unlike in the case of an infinite population, the average fitness in a finite population is maximized at a small…

Biological Physics · Physics 2009-11-07 Paulo R. A. Campos , Christoph Adami , Claus O. Wilke

We study numerically the behavior of RNA secondary structures under influence of a varying external force. This allows to measure the work $W$ during the resulting fast unfolding and refolding processes. Here, we investigate a medium-size…

Statistical Mechanics · Physics 2021-09-15 Peter Werner , Alexander K. Hartmann

This paper introduces a variational formulation of natural selection, paying special attention to the nature of "things" and the way that different "kinds" of "things" are individuated from - and influence - each other. We use the Bayesian…

Populations and Evolution · Quantitative Biology 2023-07-05 Karl Friston , Daniel Ari Friedman , Axel Constant , V. Bleu Knight , Thomas Parr , John O. Campbell

When studying the dynamics of trait distribution of populations in a heterogeneous environment, classical models from quantitative genetics choose to look at its system of moments, specifically the first two ones. Additionally, in order to…

Populations and Evolution · Quantitative Biology 2020-12-21 Léonard Dekens

A new delay equation is introduced to describe the punctuated evolution of complex nonlinear systems. A detailed analytical and numerical investigation provides the classification of all possible types of solutions for the dynamics of a…

Adaptation and Self-Organizing Systems · Physics 2015-05-13 V. I. Yukalov , E. P. Yukalova , D. Sornette

In this paper, we discuss the fitness landscape evolution of permanent replicator systems using a hypothesis that the specific time of evolutionary adaptation of the system parameters is much slower than the time of internal evolutionary…

Populations and Evolution · Quantitative Biology 2019-11-11 Sergei Drozhzhin , Tatiana Yakushkina , Alexander Bratus

We investigate a simple quantitative genetics model subjet to a gradual environmental change from the viewpoint of the phylogenies of the living individuals. We aim to understand better how the past traits of their ancestors are shaped by…

Probability · Mathematics 2021-04-22 Vincent Calvez , Benoît Henry , Sylvie Méléard , Viet Chi Tran

The influence of migration on the stochastic dynamics of subdivided populations is still an open issue in various evolutionary models. We develop here a self-consistent mean-field-like method in order to determine the effects of migration…

Statistical Mechanics · Physics 2014-04-10 Pierangelo Lombardo , Andrea Gambassi , Luca Dall'Asta

Quasistatic evolutions of critical points of time-dependent energies exhibit piecewise smooth behavior, making them useful for modeling continuum mechanics phenomena like elastic-plasticity and fracture. Traditionally, such evolutions have…

Optimization and Control · Mathematics 2026-01-09 Stefano Almi , Massimo Fornasier , Jona Klemenc , Alessandro Scagliotti

A punctuated equilibrium model of biological evolution with relative fitness between different species being the fundamental driving force of evolution is introduced. Mutation is modeled as a fitness updating cellular automaton process…

Condensed Matter · Physics 2015-06-25 H. F. Chau , L. Mak , P. K. Kwok

The mutation and selection of regulatory DNA sequences is presented as an ideal model system of molecular evolution where genotype, phenotype, and fitness can be explicitly and independently characterized. In this theoretical study, we…

Biological Physics · Physics 2007-05-23 Ulrich Gerland , Terence Hwa

We study in detail a recently proposed simple discrete model for evolution on smooth landscapes. An asymptotic solution of this model for long times is constructed. We find that the dynamics of the population are governed by correlation…

Condensed Matter · Physics 2009-10-28 David A. Kessler , Herbert Levine , Douglas Ridgway , Lev Tsimring

We study the adaptation dynamics of an initially maladapted asexual population with genotypes represented by binary sequences of length $L$. The population evolves in a maximally rugged fitness landscape with a large number of local optima.…

Populations and Evolution · Quantitative Biology 2007-05-23 Kavita Jain , Joachim Krug

We analyse a non-local parabolic integro-differential equation modelling the evolutionary dynamics of a phenotypically-structured population in a changing environment. Such models arise in a variety of contexts from climate change to…

Analysis of PDEs · Mathematics 2024-07-16 Manh Hong Duong , Fabian Spill , Blaine van Rensburg

In subdivided populations, migration acts together with selection and genetic drift and determines their evolution. Building up on a recently proposed method, which hinges on the emergence of a time scale separation between local and global…

Populations and Evolution · Quantitative Biology 2015-03-24 Pierangelo Lombardo , Andrea Gambassi , Luca Dall'Asta

We analytically study the dynamics of evolving populations that exhibit metastability on the level of phenotype or fitness. In constant selective environments, such metastable behavior is caused by two qualitatively different mechanisms.…

adap-org · Physics 2007-05-23 Erik van Nimwegen , James P. Crutchfield

The coupling between evolutionary and ecological changes (eco-evolutionary dynamics) has been shown to be relevant among diverse species, and is also of interest outside of ecology, i.e. in cancer evolution. These dynamics play an important…

Analysis of PDEs · Mathematics 2026-01-21 Manh Hong Duong , Fabian Spill , Blaine van Rensburg

We consider the effect of network structure on the evolution of a population. Models of this kind typically consider a population of fixed size and distribution. Here we consider eco-evolutionary dynamics where population size and…

Populations and Evolution · Quantitative Biology 2023-04-05 Karan Pattni , Wajid Ali , Mark Broom , Kieran J Sharkey

Our understanding of the evolutionary process has gone a long way since the publication, 150 years ago, of "On the origin of species" by Charles R. Darwin. The XXth Century witnessed great efforts to embrace replication, mutation, and…

Populations and Evolution · Quantitative Biology 2012-02-02 Susanna C. Manrubia , Jose A. Cuesta

In this paper we are concerned with the learnability of energies from data obtained by observing time evolutions of their critical points starting at random initial equilibria. As a byproduct of our theoretical framework we introduce the…

Machine Learning · Computer Science 2019-11-04 Stefano Almi , Massimo Fornasier , Richard Huber
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