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Molecular biology is a nanotechnology that works--it has worked for billions of years and in an amazing variety of circumstances. At its core is a system for acquiring, processing and communicating information that is universal, from…

Genomics · Quantitative Biology 2016-12-21 Apoorva D. Patel

It has been repeatedly proposed to expand the scope for SETI, and one of the suggested alternatives to radio is the biological media. Genomic DNA is already used on Earth to store non-biological information. Though smaller in capacity, but…

Other Quantitative Biology · Quantitative Biology 2017-06-13 Vladimir I. shCherbak , Maxim A. Makukov

A system-level genetic code is a hypothetical genetic code that exclusively or preferentially codes systems of interacting coadapted parts. System-level genetic codes differ from part-level genetic codes in which each discrete part is coded…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 John F. McGowan

It is a fascinating subject to explore how well we can understand the processes of life on the basis of fundamental laws of physics. It is emphasised that viewing biological processes as manipulation of information extracts their essential…

Quantum Physics · Physics 2007-05-23 Apoorva Patel

The sequence of nucleotide bases occurring in an organism's DNA is often regarded as a codescript for its construction. However, information in a DNA sequence can only be regarded as a codescript relative to an operational biochemical…

Other Quantitative Biology · Quantitative Biology 2013-08-12 Peter R. Wills

The standard genetic code multiplet structure as well as the correct degeneracies, class by class, are all extracted from the (unique) number 23, the order of the permutation group of 23 objects.

Other Quantitative Biology · Quantitative Biology 2008-09-01 Tidjani Negadi

The structure of the genetic code is discussed in formal terms. A rectangular table of the code ("the code matrix"), whose properties reveal its arithmetical content tagged with the information symbols in several notations. New parameters…

Other Quantitative Biology · Quantitative Biology 2009-07-22 Felix Filatov

The problem of the directionality of genome evolution is studied. Based on the analysis of C-value paradox and the evolution of genome size we propose that the function-coding information quantity of a genome always grows in the course of…

Genomics · Quantitative Biology 2015-05-13 Liaofu Luo

Information is a key concept in evolutionary biology. Information is stored in biological organism's genomes, and used to generate the organism as well as to maintain and control it. Information is also "that which evolves". When a…

Populations and Evolution · Quantitative Biology 2012-07-25 Christoph Adami

A representation of the genetic code as a six-dimensional Boolean hypercube is proposed. It is assumed here that this structure is the result of the hierarchical order of the interaction energies of the bases in codon-anticodon recognition.…

Soft Condensed Matter · Physics 2007-05-23 Miguel A. Jimenez-Montano , Carlos R. de la Mora-Basanez , Thorsten Poeschel

In this work it is shown that 20 canonical amino acids (AAs) within genetic code appear to be a whole system with strict AAs positions; more exactly, with AAs ordinal number in three variants; first variant 00-19, second 00-21 and third…

Other Quantitative Biology · Quantitative Biology 2015-06-26 Zvonimir M. Damjanovic , Miloje M. Rakocevic

Predictive coding offers a potentially unifying account of cortical function -- postulating that the core function of the brain is to minimize prediction errors with respect to a generative model of the world. The theory is closely related…

Artificial Intelligence · Computer Science 2022-07-14 Beren Millidge , Anil Seth , Christopher L Buckley

We propose a physical model to describe the mechanisms of two major scenarios of the genetic code evolution, the codon capture and ambiguous intermediate scenarios, in a consistent manner. We sketch the lowest dimensional version of our…

Populations and Evolution · Quantitative Biology 2009-09-30 Tatsuro Yamashita , Osamu Narikiyo

Scientists have been trying to identify all of the genes in the human genome since the initial draft of the genome was published in 2001. Over the intervening years, much progress has been made in identifying protein-coding genes, and the…

Rich information on the prebiotic evolution is still stored in contemporary genomic data. The statistical mechanism at the sequence level may play a significant role in the prebiotic evolution. Based on statistical analysis of genome…

Other Quantitative Biology · Quantitative Biology 2018-07-12 Dirson Jian Li

Many of life's most fascinating phenomena emerge from interactions among many elements--many amino acids determine the structure of a single protein, many genes determine the fate of a cell, many neurons are involved in shaping our thoughts…

Quantitative Methods · Quantitative Biology 2011-11-28 Thierry Mora , William Bialek

In this work it is shown that 20 canonical amino acids (AAs) within genetic code appear to be a whole system with strict distinction in Genetic Code Table (GCT) into some different quantums: 20, 23, 61 amino acid molecules. These molecules…

Biomolecules · Quantitative Biology 2019-09-23 Miloje M. Rakocevic

Relation of genome sizes to organisms complexity is still described rather equivocally. Neither the number of genes (G-value), nor the total amount of DNA (C-value) correlates consistently with phenotype complexity. Using information theory…

Genomics · Quantitative Biology 2007-05-23 Dmitri V. Parkhomchuk

It is presented that the positions of amino acids within Genetic Code Table follow from strict their physical and chemical properties as well as from a pure formal determination by the Golden mean.

Biomolecules · Quantitative Biology 2009-04-08 Miloje M. Rakocevic

Proteins employ the information stored in the genetic code and translated into their sequences to carry out well-defined functions in the cellular environment. The possibility to encode for such functions is controlled by the balance…

Biomolecules · Quantitative Biology 2018-05-24 A. Possenti , M. Vendruscolo , C. Camilloni , G. Tiana