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Computational models of the cardiovascular system are increasingly used for the diagnosis, treatment, and prevention of cardiovascular disease. Before being used for translational applications, the predictive abilities of these models need…

Applications · Statistics 2024-01-11 Friederike Schäfer , Daniele E. Schiavazzi , Leif Rune Hellevik , Jacob Sturdy

Simulations are becoming ever more common as a tool for designing complex products. Sensitivity analysis techniques can be applied to these simulations to gain insight, or to reduce the complexity of the problem at hand. However, these…

Other Computer Science · Computer Science 2017-02-03 Tom Van Steenkiste , Joachim van der Herten , Ivo Couckuyt , Tom Dhaene

Global sensitivity metrics are essential tools for assessing parameter importance in complex models, particularly when precise information about parameter values is unavailable. In many cases, such metrics are used to provide parameter…

Statistics Theory · Mathematics 2025-11-19 Huiyan Zou , Allison L. Lewis

Given-data methods for variance-based sensitivity analysis have significantly advanced the feasibility of Sobol' index computation for computationally expensive models and models with many inputs. However, the limitations of existing…

Machine Learning · Statistics 2025-09-16 Teresa Portone , Bert Debusschere , Samantha Yang , Emiliano Islas-Quinones , T. Patrick Xiao

Variance-based Sobol' sensitivity is one of the most well-known measures in global sensitivity analysis (GSA). However, uncertainties with certain distributions, such as highly skewed distributions or those with a heavy tail, cannot be…

Numerical Analysis · Mathematics 2025-02-12 Jiannan Yang

We propose a new statistical estimation framework for a large family of global sensitivity analysis indices. Our approach is based on rank statistics and uses an empirical correlation coefficient recently introduced by Chatterjee [9]. We…

Methodology · Statistics 2026-05-25 Fabrice Gamboa , Pierre Gremaud , Thierry Klein , Agnès Lagnoux

Inspired by the well-established variance-based methods for global sensitivity analysis, we develop a local total sensitivity index that decomposes the global total sensitivity conditions by independent variables' values. We employ this…

Methodology · Statistics 2021-07-21 Brian W. Bush , Joanne Wendelberger , Rebecca Hanes

Variance-based global sensitivity analysis (GSA) can provide a wealth of information when applied to complex models. A well-known Achilles' heel of this approach is its computational cost which often renders it unfeasible in practice. An…

Numerical Analysis · Mathematics 2026-01-08 John Darges , Alen Alexanderian , Pierre Gremaud

Global sensitivity analysis (GSA) is frequently used to analyze the influence of uncertain parameters in mathematical models and simulations. In principle, tools from GSA may be extended to analyze the influence of parameters in statistical…

Computation · Statistics 2018-06-29 Joseph Hart , Julie Bessac , Emil Constantinescu

We propose a new statistical estimation framework for a large family of global sensitivity analysis methods. Our approach is based on rank statistics and uses an empirical correlation coefficient recently introduced by Sourav Chatterjee. We…

Statistics Theory · Mathematics 2023-06-29 Fabrice Gamboa , Pierre Gremaud , Thierry Klein , Agnès Lagnoux

Complex computer codes are often too time expensive to be directly used to perform uncertainty propagation studies, global sensitivity analysis or to solve optimization problems. A well known and widely used method to circumvent this…

Applications · Statistics 2008-04-06 Amandine Marrel , Bertrand Iooss , Francois Van Dorpe , Elena Volkova

Global sensitivity analysis (GSA) of numerical simulators aims at studying the global impact of the input uncertainties on the output. To perform the GSA, statistical tools based on inputs/output dependence measures are commonly used. We…

Statistics Theory · Mathematics 2019-02-20 Anouar Meynaoui , Amandine Marrel , Béatrice Laurent

This paper presents a simple noise correction method for Sobol' indices estimation. Sobol' indices, especially total Sobol' indices are quite sensitive to the noise in the output and tend to be severly biased (overestimated) if no noise…

Computation · Statistics 2018-04-04 Pavel Prikhodko , Nikita Kotlyarov

In this paper, we study sensitivity indices for independent groups of variables and we look at the particular case of block-additive models. We show in this case that most of the Sobol indices are equal to zero and that Shapley effects can…

Statistics Theory · Mathematics 2018-12-12 Baptiste Broto , François Bachoc , Marine Depecker , Jean-Marc Martinez

We define and study a generalization of Sobol sensitivity indices for the case of a vector output.

Applications · Statistics 2013-04-18 Fabrice Gamboa , Alexandre Janon , Thierry Klein , Agnès Lagnoux

Chaos expansions are widely used in global sensitivity analysis (GSA), as they leverage orthogonal bases of L2 spaces to efficiently compute Sobol' indices, particularly in data-scarce settings. When derivatives are available, we argue that…

Statistics Theory · Mathematics 2025-10-06 O Roustant , N Lüthen , D Heredia , B Sudret

The hierarchically orthogonal functional decomposition of any measurable function f of a random vector X=(X_1,...,X_p) consists in decomposing f(X) into a sum of increasing dimension functions depending only on a subvector of X. Even when…

Applications · Statistics 2014-05-22 Gaelle Chastaing , Clémentine Prieur , Fabrice Gamboa

In the context of sensitivity analysis of complex phenomena in presence of uncertainty, we motivate and precise the idea of orienting the analysis towards a critical domain of the studied phenomenon. We make a brief history of related…

Methodology · Statistics 2018-04-02 Hugo Raguet , Amandine Marrel

This article presents a general multivariate $f$-sensitivity index, rooted in the $f$-divergence between the unconditional and conditional probability measures of a stochastic response, for global sensitivity analysis. Unlike the…

Numerical Analysis · Mathematics 2015-12-09 Sharif Rahman

The main objective of this paper is to estimate optimally Sobol' indices at any order when a unique input/output i.i.d.\ sample is available. Our approach stands on three main ingredients: semi-parametric estimation theory, high-order…

Statistics Theory · Mathematics 2025-11-10 Sébastien Da Veiga , Fabrice Gamboa , Thierry Klein , Agnès Lagnoux , Clémentine Prieur
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