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The broad abundance of time series data, which is in sharp contrast to limited knowledge of the underlying network dynamic processes that produce such observations, calls for a rigorous and efficient method of causal network inference. Here…

Information Theory · Computer Science 2015-05-19 Jie Sun , Dane Taylor , Erik M. Bollt

Gene regulatory networks (GRNs) represent the causal relationships between transcription factors (TFs) and target genes in single-cell RNA sequencing (scRNA-seq) data. Understanding these networks is crucial for uncovering disease…

Artificial Intelligence · Computer Science 2024-10-22 Tejumade Afonja , Ivaxi Sheth , Ruta Binkyte , Waqar Hanif , Thomas Ulas , Matthias Becker , Mario Fritz

In the post-crisis era, financial regulators and policymakers are increasingly interested in data-driven tools to measure systemic risk and to identify systemically important firms. Granger Causality (GC) based techniques to build networks…

Statistical Finance · Quantitative Finance 2022-07-27 Kara Karpman , Samriddha Lahiry , Diganta Mukherjee , Sumanta Basu

In this paper we construct an inferential procedure for Granger causality in high-dimensional non-stationary vector autoregressive (VAR) models. Our method does not require knowledge of the order of integration of the time series under…

Econometrics · Economics 2023-09-18 Alain Hecq , Luca Margaritella , Stephan Smeekes

There is growing interest in the study of causal methods in the Earth sciences. However, most applications have focused on causal discovery, i.e. inferring the causal relationships and causal structure from data. This paper instead examines…

Atmospheric and Oceanic Physics · Physics 2021-05-04 Adam Massmann , Pierre Gentine , Jakob Runge

The multiple-subject vector autoregression (multi-VAR) model captures heterogeneous network Granger causality across subjects by decomposing individual sparse VAR transition matrices into commonly shared and subject-unique paths. The model…

Methodology · Statistics 2025-10-17 Younghoon Kim , Zachary F. Fisher , Vladas Pipiras

Causal inference is a science with multi-disciplinary evolution and applications. On the one hand, it measures effects of treatments in observational data based on experimental designs and rigorous statistical inference to draw causal…

Methodology · Statistics 2022-09-05 Jingying Zeng , Run Wang

Causal variables in Markov boundary (MB) have been widely applied in extensive single-label tasks. While few researches focus on the causal variable discovery in multi-label data due to the complex causal relationships. Since some variables…

Machine Learning · Computer Science 2020-11-10 Xingyu Wu , Bingbing Jiang , Yan Zhong , Huanhuan Chen

Despite theoretical advantages, causal methods for Gene Regulatory Network (GRN) inference from single-cell RNA-seq data consistently fail to match or outperform correlation-based baselines in many realistic benchmarks, a persistent puzzle…

Machine Learning · Computer Science 2026-05-07 Miguel Fernandez-de-Retana , Ruben Sanchez-Corcuera , Unai Zulaika , Aritz Bilbao-Jayo , Aitor Almeida

Sharing spectrum with a communicating incumbent user (IU) network requires avoiding interference to IU receivers. But since receivers are passive when in the receive mode and cannot be detected, the network topology can be used to predict…

Networking and Internet Architecture · Computer Science 2018-03-14 Mihir Laghate , Danijela Cabric

Graph data is becoming increasingly prevalent due to the growing demand for relational insights in AI across various domains. Organizations regularly use graph data to solve complex problems involving relationships and connections. Causal…

Machine Learning · Computer Science 2026-02-23 Simi Job , Xiaohui Tao , Taotao Cai , Haoran Xie , Jianming Yong , Xin Wang

Linear regression model (LRM) based on mean square error (MSE) criterion is widely used in Granger causality analysis (GCA), which is the most commonly used method to detect the causality between a pair of time series. However, when signals…

Methodology · Statistics 2019-02-20 Badong Chen , Rongjin Ma , Siyu Yu , Shaoyi Du , Jing Qin

We propose a novel machine learning approach for inferring causal variables of a target variable from observations. Our focus is on directly inferring a set of causal factors without requiring full causal graph reconstruction, which is…

Machine Learning · Computer Science 2025-10-01 Jang-Hyun Kim , Claudia Skok Gibbs , Sangdoo Yun , Hyun Oh Song , Kyunghyun Cho

Causality has traditionally been a scientific way to generate knowledge by relating causes to effects. From an imaginery point of view, causal graphs are a helpful tool for representing and infering new causal information. In previous…

Artificial Intelligence · Computer Science 2020-02-07 Eduardo C. Garrido-Merchán , C. Puente , A. Sobrino , J. A. Olivas

The mainstream of research in genetics, epigenetics and imaging data analysis focuses on statistical association or exploring statistical dependence between variables. Despite their significant progresses in genetic research, understanding…

Genomics · Quantitative Biology 2018-05-14 Rong Jiao , Nan Lin , Zixin Hu , David A Bennett , Li Jin , Momiao Xiong

Uncertainty quantification is central to many applications of causal machine learning, yet principled Bayesian inference for causal effects remains challenging. Standard Bayesian approaches typically require specifying a probabilistic model…

Machine Learning · Statistics 2026-03-04 Emil Javurek , Dennis Frauen , Yuxin Wang , Stefan Feuerriegel

The specific connectivity of a neuronal network is reflected in the dynamics of the signals recorded on its nodes. The analysis of how the activity in one node predicts the behaviour of another gives the directionality in their…

Quantitative Methods · Quantitative Biology 2019-11-21 Víctor J. López-Madrona , Fernanda Matias , Claudio Mirasso , Santiago Canals , Ernesto Pereda

This paper proposes a new approach for testing Granger non-causality on panel data. Instead of aggregating panel member statistics, we aggregate their corresponding p-values and show that the resulting p-value approximately bounds the type…

Inferring a cause from its effect using observed time series data is a major challenge in natural and social sciences. Assuming the effect is generated by the cause trough a linear system, we propose a new approach based on the hypothesis…

Artificial Intelligence · Computer Science 2015-03-05 Naji Shajarisales , Dominik Janzing , Bernhard Shoelkopf , Michel Besserve

Understanding the dynamics of functional brain connectivity patterns using noninvasive neuroimaging techniques is an important focus in human neuroscience. Vector autoregressive (VAR) processes and Granger causality analysis (GCA) have been…

Applications · Statistics 2022-09-16 Jingjing Fan , Kevin Sitek , Bharath Chandrasekaran , Abhra Sarkar
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