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Mutations of genetic sequences are often accompanied by their recombinations, known as phylogenetic networks. These networks are typically reconstructed from coalescent processes that may arise from optimal merging or fitting together a…

Algebraic Topology · Mathematics 2024-08-28 Paweł Dłotko , Jan Felix Senge , Anastasios Stefanou

There are few, if any, algorithms in statistical phylogenetics which are used more heavily than Felsenstein's 1973 pruning method for computing the likelihood of a tree. We present LvD, (Likelihood via Decomposition), an alternative to…

Populations and Evolution · Quantitative Biology 2026-01-28 David Bryant , Celine Scornavacca , David Swofford

Generative Adversarial Networks (GANs) are formulated as minimax game problems, whereby generators attempt to approach real data distributions by virtue of adversarial learning against discriminators. The intrinsic problem complexity poses…

Computer Vision and Pattern Recognition · Computer Science 2021-08-10 Yuesong Tian , Li Shen , Li Shen , Guinan Su , Zhifeng Li , Wei Liu

Phylogenetic networks are an extension of phylogenetic trees which are used to represent evolutionary histories in which reticulation events (such as recombination and hybridization) have occurred. A central question for such networks is…

Populations and Evolution · Quantitative Biology 2018-03-28 Andrew Francis , Vincent Moulton

In phylogenetics, phylogenetic trees are rooted binary trees, whereas phylogenetic networks are rooted arbitrary acyclic digraphs. Edges are directed away from the root and leaves are uniquely labeled with taxa in phylogenetic networks. For…

Populations and Evolution · Quantitative Biology 2016-03-30 Andreas DM Gunawan , Bhaskar DasGupta , Louxin Zhang

We introduce and analyze a new technique for model reduction for deep neural networks. While large networks are theoretically capable of learning arbitrarily complex models, overfitting and model redundancy negatively affects the prediction…

Machine Learning · Computer Science 2017-11-27 Alireza Aghasi , Afshin Abdi , Nam Nguyen , Justin Romberg

We present TripNet, a method for constructing phylogenetic networks from triplets. We will present the motivations behind our approach and its theoretical and empirical justification. To demonstrate the accuracy and efficiency of TripNet,…

Computational Engineering, Finance, and Science · Computer Science 2015-03-19 Ruzbeh Tusserkani , Changiz Eslahchi , Hadi Poormohammadi , Azin Azadi

One strategy for reconstruction of phylogenetic networks is to solve the phylogenetic network problem, which involves inferring phylogenetic trees first and subsequently computing the smallest phylogenetic network that displays all the…

Combinatorics · Mathematics 2023-09-26 Laurent Bulteau , Louxin Zhang

We consider the NP-hard Tree Containment problem that has important applications in phylogenetics. The problem asks if a given leaf-labeled network contains a subdivision of a given leaf-labeled tree. We develop a fast algorithm for the…

Computational Complexity · Computer Science 2017-02-22 Mathias Weller

Agent-based simulation platforms play a key role in enabling fast-to-run evolution experiments that can be precisely controlled and observed in detail. Availability of high-resolution snapshots of lineage ancestries from digital…

Neural and Evolutionary Computing · Computer Science 2025-08-22 Vivaan Singhvi , Joey Wagner , Emily Dolson , Luis Zaman , Matthew Andres Moreno

Code reproduction is a cornerstone of scientific validity, yet it remains a formidable challenge in computer networking research due to the scarcity of open-source implementations and the complexity of heterogeneous system architectures.…

Networking and Internet Architecture · Computer Science 2026-02-17 Yining Jiang , Yunxin Xu , Wenyun Xu , Yufan Zhu , Tangtang He , Haiying Huang , Letian Zhu , Qingyu Song , Qiang Su , Lizhao You , Lu Tang , Wanjin Feng , Yuchao Zhang , Linghe Kong , Qiao Xiang , Jiwu Shu

Recent work has proven the existence of extreme inbreeding in a European ancestry sample taken from the contemporary UK population \cite{nature_01}. This result brings our attention again to a math problem related to inbreeding family trees…

Populations and Evolution · Quantitative Biology 2021-09-08 C. Jarne , F A. Gómez Albarracín , M. Caruso

Since the advent of modern bioinformatics, the challenging, multifaceted problem of reconstructing phylogenetic history from biological sequences has hatched perennial statistical and algorithmic innovation. Studies of the phylogenetic…

Data Structures and Algorithms · Computer Science 2024-03-05 Matthew Andres Moreno , Santiago Rodriguez Papa , Emily Dolson

We consider the problem of estimating the evolutionary history of a set of species (phylogeny or species tree) from several genes. It is known that the evolutionary history of individual genes (gene trees) might be topologically distinct…

Populations and Evolution · Quantitative Biology 2016-11-18 Gautam Dasarathy , Robert Nowak , Sebastien Roch

Motivation: Laboratory gene regulatory data for a species are sporadic. Despite the abundance of gene regulatory network algorithms that employ single data sets, few algorithms can combine the vast but disperse sources of data and extract…

Genomics · Quantitative Biology 2020-08-17 Mehrzad Saremi , Maryam Amirmazlaghani

We consider the phylogenetic tree reconstruction problem with insertions and deletions (indels). Phylogenetic algorithms proceed under a model where sequences evolve down the model tree, and given sequences at the leaves, the problem is to…

Data Structures and Algorithms · Computer Science 2019-02-22 Arun Ganesh , Qiuyi Zhang

Phylogenetic networks are leaf-labelled directed acyclic graphs that are used to describe non-treelike evolutionary histories and are thus a generalization of phylogenetic trees. The hybridization number of a phylogenetic network is the sum…

Data Structures and Algorithms · Computer Science 2016-06-01 Leo van Iersel , Steven Kelk , Nela Lekić , Chris Whidden , Norbert Zeh

We propose a reinforcement-learning algorithm to tackle the challenge of reconstructing phylogenetic trees. The search for the tree that best describes the data is algorithmically challenging, thus all current algorithms for phylogeny…

Populations and Evolution · Quantitative Biology 2023-03-14 Dana Azouri , Oz Granit , Michael Alburquerque , Yishay Mansour , Tal Pupko , Itay Mayrose

Phylogenetic networks are important for the study of evolution. The number of methods to find such networks is increasing, but most such methods can only reconstruct small networks. To find bigger networks, one can attempt to combine small…

Discrete Mathematics · Computer Science 2019-12-10 Remie Janssen , Mark Jones , Yukihiro Murakami

The architecture of deep convolutional networks (CNNs) has evolved for years, becoming more accurate and faster. However, it is still challenging to design reasonable network structures that aim at obtaining the best accuracy under a…

Computer Vision and Pattern Recognition · Computer Science 2021-10-01 Lu Rao
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