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Detecting changepoints in a time series of length $N$ entails evaluating up to $2^{N-1}$ possible changepoint models, making exhaustive enumeration computationally infeasible. Genetic algorithms (GAs) provide a stochastic way to identify…

Computation · Statistics 2025-09-30 Mo Li , QiQi Lu

We propose an on-chip mid-infrared (MIR) photonic spectroscopy platform for aerosol characterization to obtain highly discriminatory information on the chemistry of aerosol particles. Sensing of aerosols is crucial for various…

Applied Physics · Physics 2020-05-12 Robin Singh , Peter Su , Lionel Kimerling , Anu Agarwal , Brian W Anthony

Deep neural networks demonstrate strong performance under aligned training-test distributions. However, real-world test data often exhibit domain shifts. Test-Time Adaptation (TTA) addresses this challenge by adapting the model to test data…

Artificial Intelligence · Computer Science 2025-08-27 Byung-Joon Lee , Jin-Seop Lee , Jee-Hyong Lee

Increasing the angular resolution of an interferometric array requires placing its elements at large separations. This often leads to sparse coverage and introduces challenges to reconstructing images from interferometric data. We introduce…

Instrumentation and Methods for Astrophysics · Physics 2024-12-04 Dimitrios Psaltis , Feryal Ozel , Yassine Ben Zineb

Network analysis is a powerful way of modeling chromatin interactions. Assortativity is a network property used in social sciences to identify factors affecting how people establish social ties. We propose a new approach, using chromatin…

Antibiotic Resistance (AR) is a critical global health challenge that necessitates the development of cost-effective, efficient, and accurate diagnostic tools. Given the genetic basis of AR, techniques such as Polymerase Chain Reaction…

Quantitative Methods · Quantitative Biology 2025-02-24 David Hagerman , Anna Johnning , Roman Naeem , Fredrik Kahl , Erik Kristiansson , Lennart Svensson

Motivation: ``Molecular signatures'' or ``gene-expression signatures'' are used to predict patients' characteristics using data from coexpressed genes. Signatures can enhance understanding about biological mechanisms and have diagnostic…

Quantitative Methods · Quantitative Biology 2007-05-23 Ramon Diaz-Uriarte

Systems biology is an inter-disciplinary field that studies systems of biological components at different scales, which may be molecules, cells or entire organism. In particular, systems biology methods are applied to understand functional…

Computational Engineering, Finance, and Science · Computer Science 2014-12-22 Thomas Cokelaer , Julio Saez-Rodriguez

The BRITE mission is a pioneering space project aimed at the long-term photometric monitoring of the brightest stars in the sky by means of a constellation of nano-satellites. Its main advantage is high photometric accuracy and time…

Functional near-infrared spectroscopy (fNIRS) is a non-invasive optical technique that measures brain activity by estimating blood oxygenation using near-infrared light. Traditionally, PsychoPy is used in many studies to send task-specific…

Human-Computer Interaction · Computer Science 2024-11-19 Shayla Sharmin , Md Fahim Abrar , Roghayeh Leila Barmaki

Analyzing array-based computations to determine data dependences is useful for many applications including automatic parallelization, race detection, computation and communication overlap, verification, and shape analysis. For sparse matrix…

Understanding the abundance pattern of metal-poor stars and the production of heavy elements through various nucleosynthesis processes offers crucial insights into the chemical evolution of the Milky Way, revealing primary sites and major…

Interstellar filaments are an important part of star formation. To understand the structure of filaments, cross-section profiles are often fitted with Plummer profiles. This profiling is often done with submm studies, such as Herschel. It…

Astrophysics of Galaxies · Physics 2015-06-05 J. Malinen , M. Juvela , M. G. Rawlings , D. Ward-Thompson , P. Palmeirim , Ph. Andre

Hematoxylin and eosin (H&E) staining is the clinical standard for assessing tissue morphology, but it lacks molecular-level diagnostic information. In contrast, immunohistochemistry (IHC) provides crucial insights into biomarker expression,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-05 Jingsong Liu , Xiaofeng Deng , Han Li , Azar Kazemi , Christian Grashei , Gesa Wilkens , Xin You , Tanja Groll , Nassir Navab , Carolin Mogler , Peter J. Schüffler

Fluorescence microscopy reveals that the contents of many (membrane-free) nuclear "bodies" exchange rapidly with the soluble pool whilst the underlying structure persists; such observations await a satisfactory biophysical explanation. To…

Biological Physics · Physics 2017-04-26 C. A. Brackley , B. Liebchen , D. Michieletto , F. Mouvet , P. R. Cook , D. Marenduzzo

As protein therapeutics play an important role in almost all medical fields, numerous studies have been conducted on proteins using artificial intelligence. Artificial intelligence has enabled data driven predictions without the need for…

Quantitative Methods · Quantitative Biology 2023-03-30 Myeonghun Lee , Kyoungmin Min

The identification and validation of therapeutic antibodies is critical for developing effective treatments for many diseases. We present a computational approach for identifying antibodies targeting GFRAL-specific receptors, receptors…

This report presents a generic image registration benchmark with automatic evaluation using landmark annotations. The key features of the BIRL framework are: easily extendable, performance evaluation, parallel experimentation, simple…

Computer Vision and Pattern Recognition · Computer Science 2020-01-22 Jiri Borovec

Accurate whole-cell and nuclear segmentation is essential for precision pathology and spatial omics, yet routine hematoxylin and eosin (H&E) staining provides limited cytoplasmic contrast, restricting analyses to nuclei. Multiplex…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Yasin Shokrollahi , Karina B. Pinao Gonzales , Elizve N. Barrientos Toro , Paul Acosta , Patient Mosaic Team , Pingjun Chen , Yinyin Yuan , Xiaoxi Pan

In computational biology and bioinformatics, the manner to understand evolution processes within various related organisms paid a lot of attention these last decades. However, accurate methodologies are still needed to discover genes…

Neural and Evolutionary Computing · Computer Science 2016-11-15 Bassam AlKindy , Christophe Guyeux , Jean-François Couchot , Michel Salomon , Jacques M. Bahi