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We introduce a framework for the reconstruction and representation of functions in a setting where these objects cannot be directly observed, but only indirect and noisy measurements are available, namely an inverse problem setting. The…

Methodology · Statistics 2020-09-15 Eardi Lila , Simon Arridge , John A. D. Aston

Autoencoders are a type of unsupervised neural networks, which can be used to solve various tasks, e.g., dimensionality reduction, image compression, and image denoising. An AE has two goals: (i) compress the original input to a…

Computer Vision and Pattern Recognition · Computer Science 2022-11-24 Firas Laakom , Jenni Raitoharju , Alexandros Iosifidis , Moncef Gabbouj

We discuss a stochastic approach for reconstructing the native structures of proteins from the knowledge of the "effective connectivity", which is a one-dimensional structural profile constructed as a linear combination of the eigenvectors…

Biological Physics · Physics 2009-01-20 Katrin Wolff , Michele Vendruscolo , Markus Porto

We introduce a new discriminant analysis method (Empirical Discriminant Analysis or EDA) for binary classification in machine learning. Given a dataset of feature vectors, this method defines an empirical feature map transforming the…

Machine Learning · Statistics 2012-10-30 Mark A. Kon , Nikolay Nikolaev

Equation Discovery techniques have shown considerable success in regression tasks, where they are used to discover concise and interpretable models (\textit{Symbolic Regression}). In this paper, we propose a new ED-based binary…

Machine Learning · Computer Science 2025-10-29 Guus Toussaint , Arno Knobbe

Descriptor generation methods using latent representations of encoder$-$decoder (ED) models with SMILES as input are useful because of the continuity of descriptor and restorability to the structure. However, it is not clear how the…

Chemical Physics · Physics 2023-04-14 Shumpei Nemoto , Tadahaya Mizuno , Hiroyuki Kusuhara

A fundamental problem associated with the task of network reconstruction from dynamical or behavioral data consists in determining the most appropriate model complexity in a manner that prevents overfitting, and produces an inferred network…

Machine Learning · Statistics 2025-03-24 Tiago P. Peixoto

Accelerating materials development requires quantitative linkages between processing, microstructure, and properties. In this work, we introduce a framework for mapping microstructure onto a low-dimensional material manifold that is…

Materials Science · Physics 2026-05-20 Simon A. Mason , Megna N. Shah , Jeffrey P. Simmons , Dennis M. Dimiduk , Stephen R. Niezgoda

In this paper, it is shown that an auto-encoder using optimal reconstruction significantly outperforms a conventional auto-encoder. Optimal reconstruction uses the conditional mean of the input given the features, under a maximum entropy…

Machine Learning · Computer Science 2021-04-16 Paul M Baggenstoss

Electron tomography is becoming an increasingly important tool in materials science for studying the three-dimensional morphologies and chemical compositions of nanostructures. The image quality obtained by many current algorithms is…

A primary interest in dynamic inverse problems is to identify the underlying temporal behaviour of the system from outside measurements. In this work we consider the case, where the target can be represented by a decomposition of spatial…

Numerical Analysis · Mathematics 2020-06-09 Simon Arridge , Pascal Fernsel , Andreas Hauptmann

We propose a method to reconstruct and cluster incomplete high-dimensional data lying in a union of low-dimensional subspaces. Exploring the sparse representation model, we jointly estimate the missing data while imposing the intrinsic…

Computer Vision and Pattern Recognition · Computer Science 2017-09-06 João Carvalho , Manuel Marques , João P. Costeira

Dual-energy computed tomography (DECT) has shown great potential and promising applications in advanced imaging fields for its capabilities of material decomposition. However, image reconstructions and decompositions under sparse views…

Medical Physics · Physics 2016-08-01 Lei Li , Ailong Cai , Linyuan Wang , Bin Yan , Hanming Zhang , Zhizhong Zheng , Wenkun Zhang , Wanli Lu , Guoen Hu

We consider the problem of joint estimation of structured inverse covariance matrices. We perform the estimation using groups of measurements with different covariances of the same unknown structure. Assuming the inverse covariances to span…

Machine Learning · Statistics 2015-11-23 Ilya Soloveychik , Ami Wiesel

Inverse design can be a useful strategy for discovering interactions that drive particles to spontaneously self-assemble into a desired structure. Here, we extend an inverse design methodology--relative entropy optimization--to determine…

Soft Condensed Matter · Physics 2018-03-16 William D. Piñeros , Beth A. Lindquist , Ryan B. Jadrich , Thomas M. Truskett

Multiscale techniques have been widely shown to potentially overcome the limitation of homogenization schemes in representing the microscopic failure mechanisms in heterogeneous media as well as their influence on their structural response…

Numerical Analysis · Mathematics 2021-08-10 Fabrizio Greco , Lorenzo Leonetti , Paolo Lonetti , Raimondo Luciano , Andrea Pranno

Ultrasound imaging faces a trade-off between image quality and hardware complexity caused by dense transducers. Sparse arrays are one popular solution to mitigate this challenge. This work proposes an end-to-end optimization framework that…

Image and Video Processing · Electrical Eng. & Systems 2026-04-01 Sergio Urrea , Adrian Basarab , Hervé Liebgott , Henry Arguello

Convolutional neural networks are increasingly being used to analyze and classify material microstructures, motivated by the possibility that they will be able to identify relevant microstructural features more efficiently and impartially…

Computational Physics · Physics 2026-01-01 Shrunal Pothagoni , Dylan Miley , Tyrus Berry , Jeremy K. Mason , Benjamin Schweinhart

Autoencoders can be challenged by spatially non-uniform sampling of image content. This is common in medical imaging, biology, and physics, where informative patterns occur rarely at specific image coordinates, as background dominates these…

Computer Vision and Pattern Recognition · Computer Science 2026-04-03 Alejandro Castañeda Garcia , Jan van Gemert , Daan Brinks , Nergis Tömen

Accurately determining the crystallographic structure of a material, organic or inorganic, is a critical primary step in material development and analysis. The most common practices involve analysis of diffraction patterns produced in…

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