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Critical points separate distinct dynamical regimes of complex systems, often delimiting functional or macroscopic phases in which the system operates. However, the long-term prediction of critical regimes and behaviors is challenging given…

Physics and Society · Physics 2025-04-15 Xiangrong Wang , Dan Lu , Zongze Wu , Weina Xu , Hongru Hou , Yanqing Hu , Yamir Moreno

A fundamental premise of statistical physics is that the particles in a physical system are interchangeable, and hence the state of each specific component is representative of the system as a whole. This assumption breaks down for complex…

Physics and Society · Physics 2025-12-16 Neil G. MacLaren , Baruch Barzel , Naoki Masuda

Neural network modules conditioned by known priors can be effectively trained and combined to represent systems with nonlinear dynamics. This work explores a novel formulation for data-efficient learning of deep control-oriented nonlinear…

Dynamical Systems · Mathematics 2021-01-07 Elliott Skomski , Soumya Vasisht , Colby Wight , Aaron Tuor , Jan Drgona , Draguna Vrabie

Many systems in biology, physics and engineering can be described by systems of ordinary differential equation containing many parameters. When studying the dynamic behavior of these large, nonlinear systems, it is useful to identify and…

Molecular Networks · Quantitative Biology 2016-04-13 Heather A. Harrington , Dhagash Mehta , Helen M. Byrne , Jonathan D. Hauenstein

Time-discrete dynamical systems on a finite state space have been used with great success to model natural and engineered systems such as biological networks, social networks, and engineered control systems. They have the advantage of being…

Combinatorics · Mathematics 2015-03-17 Alan Veliz-Cuba , Reinhard Laubenbacher

Structural changes in a network representation of a system (e.g.,different experimental conditions, time evolution), can provide insight on its organization, function and on how it responds to external perturbations. The deeper…

Data Analysis, Statistics and Probability · Physics 2021-01-04 Leonardo L. Portes , Michael Small

Models of complex networks often incorporate node-intrinsic properties abstracted as hidden variables. The probability of connections in the network is then a function of these variables. Real-world networks evolve over time, and many…

Physics and Society · Physics 2021-05-19 Harrison Hartle , Fragkiskos Papadopoulos , Dmitri Krioukov

The recent discovery of universal principles underlying many complex networks occurring across a wide range of length scales in the biological world has spurred physicists in trying to understand such features using techniques from…

Biological Physics · Physics 2015-05-13 Sitabhra Sinha

The study of network structure has uncovered signatures of the organization of complex systems. However, there is also a need to understand how to control them; for example, identifying strategies to revert a diseased cell to a healthy…

Molecular Networks · Quantitative Biology 2016-04-19 Alexander J. Gates , Luis M. Rocha

In the fields of computation and neuroscience, much is still unknown about the underlying computations that enable key cognitive functions including learning, memory, abstraction and behavior. This paper proposes a mathematical and…

Artificial Intelligence · Computer Science 2025-01-14 Jeet Singh

Identifying governing equations for a dynamical system is a topic of critical interest across an array of disciplines, from mathematics to engineering to biology. Machine learning -- specifically deep learning -- techniques have shown their…

Dynamical Systems · Mathematics 2026-05-07 Nibodh Boddupalli , Timothy Matchen , Jeff Moehlis

Metabolic networks consist of linked functional components, or modules. The mechanism underlying metabolic network modularity is of great interest not only to researchers of basic science but also to those in fields of engineering. Previous…

Molecular Networks · Quantitative Biology 2012-09-14 Kazuhiro Takemoto

We consider a dynamic social network model in which agents play repeated games in pairings determined by a stochastically evolving social network. Individual agents begin to interact at random, with the interactions modeled as games. The…

Probability · Mathematics 2007-05-23 Brian Skyrms , Robin Pemantle

This paper formulates a framework for the analysis and distributed control of interconnected systems from the behavioural perspective. The discussions are carried out from the viewpoint of set theory and the results are completely…

Systems and Control · Electrical Eng. & Systems 2021-03-19 Yitao Yan , Jie Bao , Biao Huang

Complex systems are successfully reduced to interacting elements via the network concept. Transport plays a key role in the survival of networks. For example the specialized signaling cascades of cellular networks filter noise and…

Biological Physics · Physics 2010-10-05 Robin Palotai , Peter Csermely

In general, many dynamic processes are involved with interacting variables, from physical systems to sociological analysis. The interplay of components in the system can give rise to confounding dynamic behavior. Many approaches model…

Artificial Intelligence · Computer Science 2021-06-02 Qianyu Feng , Bang Zhang , Yi Yang

Dynamic probabilistic networks are a compact representation of complex stochastic processes. In this paper we examine how to learn the structure of a DPN from data. We extend structure scoring rules for standard probabilistic networks to…

Artificial Intelligence · Computer Science 2013-02-01 Nir Friedman , Kevin Murphy , Stuart Russell

The promise of discovering a functional blueprint of a cellular system from large-scale and high-throughput sequence and experimental data is predicated on the belief that the same top-down investigative approach that proved successful in…

Molecular Networks · Quantitative Biology 2007-05-23 Riccardo Boscolo , Behnam A. Rezaei , P. Oscar Boykin , Vwani P. Roychowdhury

Genetic regulatory networks enable cells to respond to the changes in internal and external conditions by dynamically coordinating their gene expression profiles. Our ability to make quantitative measurements in these biochemical circuits…

Biological Physics · Physics 2015-03-17 Aleksandra M Walczak , Gašper Tkačik

What can we learn about controlling a system solely from its underlying network structure? Here we adapt a recently developed framework for control of networks governed by a broad class of nonlinear dynamics that includes the major dynamic…

Disordered Systems and Neural Networks · Physics 2017-07-07 Jorge G. T. Zañudo , Gang Yang , Réka Albert