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We describe an approach to online analysis of micro-rheology data using a multi-scale time-correlation method. The method is particularly suited to process high-volume data streams and compress the relevant information in real time. Using…

Soft Condensed Matter · Physics 2015-05-20 Taiki Yanagishima , Daan Frenkel , Jurij Kotar , Erika Eiser

We use a model based on the fractional Langevin equation with external noise to describe the anomalous dynamics observed in microrheology experiments in living cells. This model reproduces both the subdiffusive short-time and the…

Soft Condensed Matter · Physics 2013-07-25 Andreas Dechant , Eric Lutz

Fast and broadband spectrum sensing is an essential component in cognitive radio systems, intelligent transportation systems, electronic warfare systems, etc. However, traditional electronic-based solutions have a trade-off among the…

In this paper, we propose a Generalized Langevin Equation (GLE)-based model to describe the lateral diffusion of a protein in a lipid bilayer. The memory kernel is represented in terms of a viscous (instantaneous) and an elastic (non…

Biological Physics · Physics 2021-11-24 Loris Di Cairano , Benjamin Stamm , Vania Calandrini

Motivated by subdiffusive motion of bio-molecules observed in living cells we study the stochastic properties of a non-Brownian particle whose motion is governed by either fractional Brownian motion or the fractional Langevin equation and…

Statistical Mechanics · Physics 2016-09-08 Jae-Hyung Jeon , Ralf Metzler

Brownian motion is essential for describing diffusion in systems ranging from simple to complex liquids. Unlike simple liquids, which consist of only a solvent, complex liquids, such as colloidal suspensions or the cytoplasm of a cell, are…

Soft Condensed Matter · Physics 2025-02-27 Jeffrey C. Everts , Robert Hołyst , Karol Makuch

We report measurements of the frequency-dependent shear moduli of aging colloidal systems that evolve from a purely low-viscosity liquid to a predominantly elastic glass or gel. Using microrheology, we measure the local complex shear…

Soft Condensed Matter · Physics 2009-11-13 S. Jabbari-Farouji , M. Atakhorram , D. Mizuno , E. Eiser , G. H. Wegdam , F. C. MacKintosh , Daniel Bonn , C. F. Schmidt

Since the pioneering work of Arthur Ashkin, optical tweezers have become an indispensable tool for contactless manipulation of micro- and nanoparticles. Nowadays optical tweezers are employed in a myriad of applications demonstrating the…

Acousto-optic deflectors (AOD) enable spatiotemporal control of laser beams through diffraction at an ultrasonic grating that is controllable by radio-frequency (rf) waveforms. These devices are a widely used tool for high-bandwidth…

Optics · Physics 2025-12-19 Marcel Mittenbuehler , Lukas Sturm , Malte Schlosser , Gerhard Birkl

While being invented for precision measurement of single atomic transitions, frequency combs have also become a versatile tool for broadband spectroscopy in the last years. In this paper we present a novel and simple approach for broadband…

Optical tweezers are an invaluable tool for non-contact trapping and micro-manipulation, but their ability to facilitate high-throughput volumetric microrheology of biological samples for mechanobiology research is limited by the precise…

Instrumentation and Detectors · Physics 2021-04-07 Nichaluk Leartprapun , Rishyashring R. Iyer , Gavrielle R. Untracht , Jeffrey A. Mulligan , Steven G. Adie

Time-resolved optical spectroscopy (TR-OS) has emerged as a fundamental spectroscopic tool for probing complex materials, to both investigate ground-state-related properties and trigger phase transitions among different states with peculiar…

The rheological behavior of a material is strongly related to the energy dissipation, and the understanding and modeling of dissipation is important from the view point of rheology. To study rheological properties with some mesoscopic and…

Soft Condensed Matter · Physics 2020-05-20 Takashi Uneyama

By idealizing a general mapping as a series of local affine ones, we derive approximately transformed material parameters necessary to control solid elastic waves within classical elasticity theory. The transformed elastic moduli are…

Classical Physics · Physics 2011-11-04 Jin Hu , Zheng Chang , Gengkai Hu

A new theoretical method, referred to as Generalized Langevin Mode Analysis (GLMA), is proposed to analyze the mode of structural fluctuations of a biomolecule in solution. The method combines the two theories in the statistical mechanics,…

Statistical Mechanics · Physics 2022-05-20 Masatake Sugita , Fumio Hirata

Diffusing-Wave Spectroscopy (DWS) treats the transport of photons through turbid samples as a diffusion process, thereby making it possible to extract the dynamics of scatterers from measured correlation functions. The analysis of DWS data…

Soft Condensed Matter · Physics 2017-12-27 Zahra Fahimi , Frank Aangenendt , Panayiotis Voudouris , Johan Mattson , Hans M. Wyss

Recently, there has been interest in determining the viscoelastic properties of polymeric liquids and other complex fluids by means of Diffusing Wave Spectroscopy (DWS). In this technique, light-scattering spectroscopy is applied to highly…

Soft Condensed Matter · Physics 2024-08-27 George D. J. Phillies

Optical tweezers are powerful tools based on focused laser beams. They are able to trap, manipulate and investigate a wide range of microscopic and nanoscopic particles in different media, such as liquids, air, and vacuum. Key applications…

Optical tweezers are tools made of light that enable contactless pushing, trapping, and manipulation of objects ranging from atoms to space light sails. Since the pioneering work by Arthur Ashkin in the 1970s, optical tweezers have evolved…

Optics · Physics 2022-06-29 Giovanni Volpe , Onofrio M. Maragò , Halina Rubinzstein-Dunlop , Giuseppe Pesce , Alexander B. Stilgoe , Giorgio Volpe , Georgiy Tkachenko , Viet Giang Truong , Síle Nic Chormaic , Fatemeh Kalantarifard , Parviz Elahi , Mikael Käll , Agnese Callegari , Manuel I. Marqués , Antonio A. R. Neves , Wendel L. Moreira , Adriana Fontes , Carlos L. Cesar , Rosalba Saija , Abir Saidi , Paul Beck , Jörg S. Eismann , Peter Banzer , Thales F. D. Fernandes , Francesco Pedaci , Warwick P Bowen , Rahul Vaippully , Muruga Lokesh , Basudev Roy , Gregor Thalhammer , Monika Ritsch-Marte , Laura Pérez García , Alejandro V. Arzola , Isaac Pérez Castillo , Aykut Argun , Till M. Muenker , Bart E. Vos , Timo Betz , Ilaria Cristiani , Paolo Minzioni , Peter J. Reece , Fan Wang , David McGloin , Justus C. Ndukaife , Romain Quidant , Reece P. Roberts , Cyril Laplane , Thomas Volz , Reuven Gordon , Dag Hanstorp , Javier Tello Marmolejo , Graham D. Bruce , Kishan Dholakia , Tongcang Li , Oto Brzobohatý , Stephen H. Simpson , Pavel Zemánek , Felix Ritort , Yael Roichman , Valeriia Bobkova , Raphael Wittkowski , Cornelia Denz , G. V. Pavan Kumar , Antonino Foti , Maria Grazia Donato , Pietro G. Gucciardi , L. Gardini , G. Bianchi , A. Kashchuk , M. Capitanio , Lynn Paterson , P. H. Jones , Kirstine Berg-Sørensen , Younes F. Barooji , Lene B. Oddershede , Pegah Pouladian , Daryl Preece , Caroline Beck Adiels , Anna Chiara De Luca , A. Magazzù , D. Bronte Ciriza , M. A. Iatì , Grover A. Swartzlander

The Young\'s modulus of a nylon string has been determined experimentally by combining elasticity theory and wave optics. A diffraction experiment has been setup to determine the change in the string diameter for different tensile forces…