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Related papers: Maximum Cliques in Protein Structure Comparison

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We present a method that compares the protein interaction networks of two species to detect functionally similar (conserved) protein modules between them. The method is based on an algorithm we developed to identify matching subgraphs…

Molecular Networks · Quantitative Biology 2007-05-23 Manikandan Narayanan , Richard M. Karp

A $k$-clique is a dense graph, consisting of $k$ fully-connected nodes, that finds numerous applications, such as community detection and network analysis. In this paper, we study a new problem, that finds a maximum set of disjoint…

Social and Information Networks · Computer Science 2025-04-15 Wenqing Lin , Xin Chen , Haoxuan Xie , Sibo Wang , Siqiang Luo

Counting instances of specific subgraphs in a larger graph is an important problem in graph mining. Finding cliques of size k (k-cliques) is one example of this NP-hard problem. Different algorithms for clique counting avoid counting the…

Data Structures and Algorithms · Computer Science 2021-12-30 Amogh Lonkar , Scott Beamer

In this paper, we propose a randomized $\tilde{O}(\mu(G))$-round algorithm for the maximum cardinality matching problem in the CONGEST model, where $\mu(G)$ means the maximum size of a matching of the input graph $G$. The proposed algorithm…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-01-13 Taisuke Izumi , Naoki Kitamura , Yutaro Yamaguchi

Accurately predicting protein structures from amino acid sequences remains a fundamental challenge in computational biology, with profound implications for understanding biological functions and enabling structure-based drug discovery.…

We present CLIPPER+, an algorithm for finding maximal cliques in unweighted graphs for outlier-robust global registration. The registration problem can be formulated as a graph and solved by finding its maximum clique. This formulation…

Robotics · Computer Science 2024-02-26 Kaveh Fathian , Tyler Summers

A disk graph is an intersection graph of disks in $\mathbb{R}^2$. Determining the computational complexity of finding a maximum clique in a disk graph is a long-standing open problem. In 1990, Clark, Colbourn, and Johnson gave a…

Computational Geometry · Computer Science 2024-07-17 J. Mark Keil , Debajyoti Mondal

A matching cut is a partition of the vertex set of a graph into two sets $A$ and $B$ such that each vertex has at most one neighbor in the other side of the cut. The MATCHING CUT problem asks whether a graph has a matching cut, and has been…

Data Structures and Algorithms · Computer Science 2019-05-09 Guilherme C. M. Gomes , Ignasi Sau

One of the most difficult problems difficult problem in systems biology is to discover protein-protein interactions as well as their associated functions. The analysis and alignment of protein-protein interaction networks (PPIN), which are…

Molecular Networks · Quantitative Biology 2019-02-20 Ricardo Alberich , Adrià Alcala , Mercè Llabrés , Francesc Rosselló , Gabriel Valiente

Protein structure prediction is one of the most important problems in computational biology. The most successful computational approach, also called template-based modeling, identifies templates with solved crystal structures for the query…

Biomolecules · Quantitative Biology 2013-06-20 Jian Peng

Determining the interaction partners among protein/domain families poses hard computational problems, in particular in the presence of paralogous proteins. Available approaches aim to identify interaction partners among protein/domain…

Populations and Evolution · Quantitative Biology 2015-01-14 Iman Hajirasouliha , Alexander Schönhuth , David Juan , Alfonso Valencia , S. Cenk Sahinalp

The performance of spectral clustering heavily relies on the quality of affinity matrix. A variety of affinity-matrix-construction (AMC) methods have been proposed but they have hyperparameters to determine beforehand, which requires strong…

Machine Learning · Computer Science 2023-02-07 Jicong Fan , Yiheng Tu , Zhao Zhang , Mingbo Zhao , Haijun Zhang

Listing k-cliques plays a fundamental role in various data mining tasks, such as community detection and mining of cohesive substructures. Existing algorithms for the k-clique listing problem are built upon a general framework, which finds…

Databases · Computer Science 2025-02-04 Yehyun Nam , Jihoon Jang , Kunsoo Park , Jianye Yang , Cheng Long

The volume of image repositories continues to grow. Despite the availability of content-based addressing, we still lack a lightweight tool that allows us to discover images of distinct characteristics from a large collection. In this paper,…

Computer Vision and Pattern Recognition · Computer Science 2024-02-15 Shanfeng Hu

Listing dense subgraphs in large graphs plays a key task in varieties of network analysis applications like community detection. Clique, as the densest model, has been widely investigated. However, in practice, communities rarely form as…

Data Structures and Algorithms · Computer Science 2022-02-22 Zhengren Wang , Yi Zhou , Mingyu Xiao , Bakhadyr Khoussainov

Finding large cliques or cliques missing a few edges is a fundamental algorithmic task in the study of real-world graphs, with applications in community detection, pattern recognition, and clustering. A number of effective…

Combinatorics · Mathematics 2021-11-23 Balaram Behera , Edin Husić , Shweta Jain , Tim Roughgarden , C. Seshadhri

The fold recognition methods are promissing tools for capturing the structure of a protein by its amino acid residues sequence but their use is still restricted by the needs of huge computational resources and suitable efficient algorithms…

Quantitative Methods · Quantitative Biology 2007-07-30 Rumen Andonov , Guillaume Collet , Jean-François Gibrat , Antoine Marin , Vincent Poirriez , Nikola Yanev

Network embedding, a graph representation learning method illustrating network topology by mapping nodes into lower-dimension vectors, is challenging to accommodate the ever-changing dynamic graphs in practice. Existing research is mainly…

Social and Information Networks · Computer Science 2023-06-16 Haoran Deng , Yang Yang , Jiahe Li , Haoyang Cai , Shiliang Pu , Weihao Jiang

This paper studies the maximum cardinality matching problem in stochastically evolving graphs. We formally define the arrival-departure model with stochastic departures. There, a graph is sampled from a specific probability distribution and…

Data Structures and Algorithms · Computer Science 2020-05-19 Eleni C. Akrida , Argyrios Deligkas , George B. Mertzios , Paul G. Spirakis , Viktor Zamaraev

We implement a new algorithm for listing all maximal cliques in sparse graphs due to Eppstein, L\"offler, and Strash (ISAAC 2010) and analyze its performance on a large corpus of real-world graphs. Our analysis shows that this algorithm is…

Data Structures and Algorithms · Computer Science 2011-03-03 David Eppstein , Darren Strash
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