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In recent years the machine learning techniques have shown a great potential in various problems from a multitude of disciplines, including materials design and drug discovery. The high computational speed on the one hand and the accuracy…

Chemical Physics · Physics 2018-05-09 Konstantin Gubaev , Evgeny V. Podryabinkin , Alexander V. Shapeev

The modeling of atomistic biomolecular simulations using kinetic models such as Markov state models (MSMs) has had many notable algorithmic advances in recent years. The variational principle has opened the door for a nearly fully automated…

Biological Physics · Physics 2019-11-26 Martin K. Scherer , Brooke E. Husic , Moritz Hoffmann , Fabian Paul , Hao Wu , Frank Noé

Embedding artificial intelligence into systems introduces significant challenges to modern engineering practices. Hazard analysis tools and processes have not yet been adequately adapted to the new paradigm. This paper describes initial…

Software Engineering · Computer Science 2022-03-30 Nikolas Martelaro , Carol J. Smith , Tamara Zilovic

Chemical synthesis remains a critical bottleneck in the discovery and manufacture of functional small molecules. AI-based synthesis planning models could be a potential remedy to find effective syntheses, and have made progress in recent…

The Q-method has been utilized over time in various areas, including information systems. In this study, we used a systematic mapping to illustrate how the Q-method was applied within Information Systems (IS) community and proposing towards…

Human-Computer Interaction · Computer Science 2019-08-30 Irawan Nurhas , Stefan Geisler , Jan Pawlowski

Machine learning offers an exciting opportunity to improve the calibration of nearly all reconstructed objects in high-energy physics detectors. However, machine learning approaches often depend on the spectra of examples used during…

High Energy Physics - Phenomenology · Physics 2022-09-02 Rikab Gambhir , Benjamin Nachman , Jesse Thaler

Artificial intelligence is beginning to reduce the manual effort in the CAD-to-mesh pipeline. Written for meshing and geometry practitioners with limited AI background, this survey organizes recent work by workflow step. We cover part…

Computational Engineering, Finance, and Science · Computer Science 2026-02-03 Steven Owen , Nathan Brown , Nikos Chrisochoides , Rao Garimella , Xianfeng Gu , Franck Ledoux , Na Lei , Roshan Quadros , Navamita Ray , Nicolas Winovich , Yongjie Jessica Zhang

AI Planning, Machine Learning and Process Mining have so far developed into separate research fields. At the same time, many interesting concepts and insights have been gained at the intersection of these areas in recent years. For example,…

Artificial Intelligence · Computer Science 2022-08-19 Peter Fettke , Alexander Rombach

In order to achieve state-of-the-art performance, modern machine learning techniques require careful data pre-processing and hyperparameter tuning. Moreover, given the ever increasing number of machine learning models being developed, model…

Machine Learning · Statistics 2018-05-03 Nicolo Fusi , Rishit Sheth , Huseyn Melih Elibol

Self-supervised pre-training is gaining increasingly more popularity in AI-aided drug discovery, leading to more and more pre-trained models with the promise that they can extract better feature representations for molecules. Yet, the…

Biomolecules · Quantitative Biology 2022-09-16 Ziqiao Zhang , Yatao Bian , Ailin Xie , Pengju Han , Long-Kai Huang , Shuigeng Zhou

Predicting the outcome of a chemical reaction using efficient computational models can be used to develop high-throughput screening techniques. This can significantly reduce the number of experiments needed to be performed in a huge search…

Artificial intelligence (AI) has been widely applied in drug discovery with a major task as molecular property prediction. Despite booming techniques in molecular representation learning, key elements underlying molecular property…

Quantitative Methods · Quantitative Biology 2023-09-06 Jianyuan Deng , Zhibo Yang , Hehe Wang , Iwao Ojima , Dimitris Samaras , Fusheng Wang

Gaussian process regression is a powerful method for predicting states based on given data. It has been successfully applied for probabilistic predictions of structural systems to quantify, for example, the crack growth in mechanical…

Machine Learning · Statistics 2022-06-20 Simon Pfingstl , Markus Zimmermann

\textit{Indirect Immunofluorescence Imaging of Human Epithelial Type 2} (HEp-2) cells is an effective way to identify the presence of Anti-Nuclear Antibody (ANA). Most existing works on HEp-2 cell classification mainly focus on feature…

Computer Vision and Pattern Recognition · Computer Science 2015-09-09 Xianbiao Qi , Guoying Zhao , Jie Chen , Matti Pietikäinen

The first step in the construction of a regression model or a data-driven analysis, aiming to predict or elucidate the relationship between the atomic scale structure of matter and its properties, involves transforming the Cartesian…

High-throughput approximations of quantum mechanics calculations and combinatorial experiments have been traditionally used to reduce the search space of possible molecules, drugs and materials. However, the interplay of structural and…

Quantum Physics · Physics 2019-10-29 Alain Tchagang , Julio Valdés

Microstructures of a material form the bridge linking processing conditions - which can be controlled, to the material property - which is the primary interest in engineering applications. Thus a critical task in material design is…

Image and Video Processing · Electrical Eng. & Systems 2019-10-08 Akshay Iyer , Biswadip Dey , Arindam Dasgupta , Wei Chen , Amit Chakraborty

Datasets in the Natural Sciences are often curated with the goal of aiding scientific understanding and hence may not always be in a form that facilitates the application of machine learning. In this paper, we identify three trends within…

Chemical Physics · Physics 2021-05-07 Ryan-Rhys Griffiths , Philippe Schwaller , Alpha A. Lee

Data Assimilation is the process in which we improve the representation of the state of a physical system by combining information coming from a numerical model, real-world observations, and some prior modelling. It is widely used to model…

Optimization and Control · Mathematics 2025-01-09 Victor Trappler , Arthur Vidard

Humans naturally follow distinct patterns when conducting their daily activities, which are driven by established practices and processes, such as production workflows, social norms and daily routines. Human activity recognition (HAR)…

Artificial Intelligence · Computer Science 2024-11-14 Jiawei Zheng , Petros Papapanagiotou , Jacques D. Fleuriot , Jane Hillston