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Surface roughness plays a crucial role in the accuracy of indentation experiments used to measure the elastic properties of materials. In this study, we present a computational analysis of how surface roughness, represented explicitly by…

Computational Physics · Physics 2024-10-24 D. F. S. Costa , J. H. M Pontes , W. P. Ferreira , J. S. de Sousa , C. L. N. Oliveira

Recent advances in (scanning) transmission electron microscopy have enabled routine generation of large volumes of high-veracity structural data on 2D and 3D materials, naturally offering the challenge of using these as starting inputs for…

Data Analysis, Statistics and Probability · Physics 2022-11-08 Ayana Ghosh , Maxim Ziatdinov , Ondrej Dyck , Bobby Sumpter , Sergei V. Kalinin

Soft materials, such as liquids, polymers, foams, gels, colloids, granular materials, and most soft biological materials, play an important role in our daily lives. From a mechanical viewpoint, soft materials can easily achieve large…

Soft Condensed Matter · Physics 2022-12-16 Shengyou Yang , Pradeep Sharma

Bayesian methods have been very successful in quantifying uncertainty in physics-based problems in parameter estimation and prediction. In these cases, physical measurements y are modeled as the best fit of a physics-based model…

Data Analysis, Statistics and Probability · Physics 2015-02-06 Dave Higdon , Jordan D. McDonnell , Nicolas Schunck , Jason Sarich , Stefan M. Wild

Detecting a change point is a crucial task in statistics that has been recently extended to the quantum realm. A source state generator that emits a series of single photons in a default state suffers an alteration at some point and starts…

Changepoint detection methods are used in many areas of science and engineering, e.g., in the analysis of copy number variation data, to detect abnormalities in copy numbers along the genome. Despite the broad array of available tools,…

Methodology · Statistics 2018-12-11 Sangwon Hyun , Kevin Lin , Max G'Sell , Ryan J. Tibshirani

We introduce a novel Bayesian method that can detect multiple structural breaks in the mean and variance of a length $T$ time-series. Our method quantifies uncertainty by returning $\alpha$-level credible sets around the estimated locations…

Methodology · Statistics 2025-07-14 Davis Berlind , Lorenzo Cappello , Oscar Hernan Madrid Padilla

Soft tissues - such as ligaments and tendons - primarily consist of solid (collagen, predominantly) and liquid phases. Understanding the interaction between such components and how they change under physiological loading sets the basis for…

We propose the first Bayesian methods for detecting change points in high-dimensional mean and covariance structures. These methods are constructed using pairwise Bayes factors, leveraging modularization to identify significant changes in…

Methodology · Statistics 2024-11-25 Jaehoon Kim , Kyoungjae Lee , Lizhen Lin

Experiments aimed at searching for variations in the fine-structure constant $\alpha$ are based on spectroscopy of transitions in microscopic bound systems, such as atoms and ions, or resonances in optical cavities. The sensitivities of…

Atomic Physics · Physics 2023-05-22 Beata Zjawin , Marcin Bober , Roman Ciuryło , Daniel Lisak , Michał Zawada , Piotr Wcisło

We propose a multi-metric flexible Bayesian framework to support efficient interim decision-making in multi-arm multi-stage phase II clinical trials. Multi-arm multi-stage phase II studies increase the efficiency of drug development, but…

Applications · Statistics 2023-12-15 Suzanne M. Dufault , Angela M. Crook , Katie Rolfe , Patrick P. J. Phillips

This study develops a Bayesian, uncertainty-aware framework for tendon breakage localization in pre-stressed concrete members using high-resolution data from distributed fiber-optic sensors (DFOS). DFOS enable full-field monitoring of…

Computational Engineering, Finance, and Science · Computer Science 2026-04-10 Daniel Andrés Arcones , Aeneas Paul , Martin Weiser , David Sanio , Peter Mark , Jörg F. Unger

The so-called indentation stiffness tomography technique for detecting the interior mechanical properties of an elastic sample with an inhomogeneity is analyzed in the framework of the asymptotic modeling approach under the assumption of…

Analysis of PDEs · Mathematics 2013-11-22 Ivan Argatov

Automated identification of protein conformational states from simulation of an ensemble of structures is a hard problem because it requires teaching a computer to recognize shapes. We adapt the naive Bayes classifier from the machine…

Computational Physics · Physics 2020-12-02 David M. Rogers

Diagnosis based on medical images, such as X-ray images, often involves manual annotation of anatomical keypoints. However, this process involves significant human efforts and can thus be a bottleneck in the diagnostic process. To fully…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Jinhee Kim , Taesung Kim , Taewoo Kim , Jaegul Choo , Dong-Wook Kim , Byungduk Ahn , In-Seok Song , Yoon-Ji Kim

In this paper, we present a methodology that uses an optical tactile sensor for efficient tactile exploration of embedded objects within soft materials. The methodology consists of an exploration phase, where a probabilistic estimate of the…

Robotics · Computer Science 2024-04-01 Jose A. Solano-Castellanos , Won Kyung Do , Monroe Kennedy

Atomic force microscopes have proved to be fundamental research tools in many situations where a gentle imaging process is required, and in a variety of environmental conditions, such as the study of biological samples. Among the possible…

Systems and Control · Computer Science 2023-01-05 Marco Coraggio , Martin Homer , Oliver D. Payton , Mario di Bernardo

The classical problem of indentation on an elastic substrate has found new applications in the field of the Atomic Force Microscopy. However, linearly elastic indentation models are not sufficiently accurate to predict the…

Soft Condensed Matter · Physics 2022-12-14 Yangkun Du , Peter Stewart , Nicholas A Hill , Huabing Yin , Raimondo Penta , Jakub Kory , Xiaoyu Luo , Raymond Ogden

Information about the physical properties of astrophysical objects cannot be measured directly but is inferred by interpreting spectroscopic observations in the context of atomic physics calculations. Ratios of emission lines, for example,…

Nanoindentation involves probing a hard diamond tip into a material, where the load and the displacement experienced by the tip is recorded continuously. This load-displacement data is a direct function of material's innate stress-strain…

Computational Engineering, Finance, and Science · Computer Science 2016-12-13 Salah U. Hamim