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Self-assembly is a fundamental concept in biology and of significant interest to nanotechnology. Significant progress has been made in characterizing and controlling the properties of the resulting structures, both experimentally and…

Soft Condensed Matter · Physics 2024-03-06 Florian M. Gartner , Erwin Frey

Soft colloids allow to explore high density states well beyond random close packing. An important open question is whether softness controls the dynamics under these dense conditions. While experimental works reported conflicting results,…

Soft Condensed Matter · Physics 2021-06-08 Nicoletta Gnan , Emanuela Zaccarelli

We present an analytically solvable model for self-assembly of a molecular complex on a filament. The process is driven by a seed molecule that undergoes facilitated diffusion, which is a search strategy that combines diffusion in…

Statistical Mechanics · Physics 2015-11-04 Ziya Kalay

In this study, we present a comprehensive exploration of formation of different phases in lipid molecules using a coarse-grained implicit solvent model, where each lipid molecule is represented as a rigid, three-bead rod-like structure. Our…

Soft Condensed Matter · Physics 2023-12-13 Biplab Bawali , Alokmay Datta , Jayashree Saha

We perform numerical simulations to study self-assembly of nanoparticles mediated by an elastic planar surface. We show how the nontrivial elastic response to deformations of these surfaces leads to anisotropic interactions between the…

Soft Condensed Matter · Physics 2012-01-04 Andela Šarić , Angelo Cacciuto

From the analysis of sizes of approximately 130 small icosahedral viruses we find that there is a typical structural capsid protein, having a mean diameter of 5 nm and a mean thickness of 3 nm, with more than two thirds of the analyzed…

Biological Physics · Physics 2013-07-16 Anze Losdorfer Bozic , Antonio Siber , Rudolf Podgornik

The question of how stiff polymers are able to pack into small containers is particularly relevant to the study of DNA packaging in viruses. A reduced version of the problem based on coarse-grained representations of the main components of…

Biomolecules · Quantitative Biology 2016-10-12 D. C. Rapaport

The growth dynamics of rigid biopolymers, consisting of $N$ parallel protofilaments, is investigated theoretically using simple approximate models. In our approach, the structure of a polymer's growing end and lateral interactions between…

Statistical Mechanics · Physics 2009-11-10 Evgeny B. Stukalin , Anatoly B. Kolomeisky

We demonstrate a simple method by which time-dependent interactions can be exploited to improve self-assembly in colloidal systems. We apply this method to two systems: a model colloid with short-ranged attractive potentials that undergoes…

Soft Condensed Matter · Physics 2017-09-13 Christopher J. Fullerton , Robert L. Jack

We examine the budding of a nanoscale particle through a lipid bilayer using molecular dynamics simulations, free energy calculations, and an elastic theory, with the aim of determining the extent to which equilibrium elasticity theory can…

Subcellular Processes · Quantitative Biology 2012-02-22 Teresa Ruiz-Herrero , Enrique Velasco , Michael F. Hagan

The field of complex self-assembly is moving toward the design of multi-particle structures consisting of thousands of distinct building blocks. To exploit the potential benefits of structures with such `addressable complexity,' we need to…

Soft Condensed Matter · Physics 2015-06-02 William M. Jacobs , Aleks Reinhardt , Daan Frenkel

We present a top-down approach to the study of the dynamics of icosahedral virus capsids, in which each protein is approximated by a point mass. Although this represents a rather crude coarse-graining, we argue that it highlights several…

Biomolecules · Quantitative Biology 2008-08-20 Kasper Peeters , Anne Taormina

We study the mathematical properties of a general model of cell division structured with several internal variables. We begin with a simpler and specific model with two variables, we solve the eigenvalue problem with strong or weak…

Analysis of PDEs · Mathematics 2008-10-08 Marie Doumic Jauffret

The inverse geometric approach to the modeling of the growth of circular objects revealing required features, such as the velocity of the growth and fractal behavior of their contours, is presented. It enables to reproduce some of the…

Medical Physics · Physics 2007-05-23 Branislav Brutovsky , Denis Horvath , Vladimir Lisy

A simple model of an active colloid consisting of dumbbell-shaped particles that cyclically change their length without propelling themselves is proposed and analyzed. At nanoscales, it represents an idealization for bacterial cytoplasm or…

Adaptation and Self-Organizing Systems · Physics 2020-01-28 Yuki Koyano , Hiroyuki Kitahata , Alexander S. Mikhailov

We develop a multi-scale approach to simulate hydrated nanobio systems under realistic condi- tions (e.g., nanoparticles and protein solutions at physiological conditions over time-scales up to hours). We combine atomistic simulations of…

Soft Condensed Matter · Physics 2017-07-05 Oriol Vilanova , Valentino Bianco , Giancarlo Franzese

A model of a discrete pregeometry on a microscopic scale is introduced. This model is a finite network of finite elementary processes. The mathematical description is a d-graph that is a generalization of a graph. This is the particular…

General Relativity and Quantum Cosmology · Physics 2010-04-29 Alexey L. Krugly

We explore the self-assembly process of colloidal structures immersed in active baths. By considering low-valence particles we numerically investigate the irreversible aggregation dynamics originated by the presence of run-and-tumble…

Soft Condensed Matter · Physics 2019-01-30 Luca Angelani

Microgels are colloidal-scale particles individually made of crosslinked polymer networks that can swell and deswell in response to external stimuli, such as changes to temperature or pH. Despite a large amount of experimental activities on…

Soft Condensed Matter · Physics 2019-02-08 Nicoletta Gnan , Lorenzo Rovigatti , Maxime Bergman , Emanuela Zaccarelli

The spongy mesophyll is a complex, porous tissue found in plant leaves that enables carbon capture and provides mechanical stability. Unlike many other biological tissues, which remain confluent throughout development, the spongy mesophyll…

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