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Linear stability of synchronized states in networks of delay-coupled oscillators depends on the type of interaction, the network and oscillator properties. For inert oscillator response, found ubiquitously from biology to engineering,…

Adaptation and Self-Organizing Systems · Physics 2022-02-02 Dimitrios Prousalis , Lucas Wetzel

We investigate the stability properties of two different classes of metabolic cycles using a combination of analytical and computational methods. Using principles from structural kinetic modeling (SKM), we show that the stability of…

Molecular Networks · Quantitative Biology 2010-07-29 Ed Reznik , Daniel Segrè

The process of pattern formation for a multi-species model anchored on a time varying network is studied. A non homogeneous perturbation superposed to an homogeneous stable fixed point can amplify, as follows a novel mechanism of…

Statistical Mechanics · Physics 2017-10-11 Julien Petit , Ben Lauwens , Duccio Fanelli , Timoteo Carletti

Identifiability conditions for single or multiple modules in a dynamic network specify under which conditions the considered modules can be uniquely recovered from the second-order statistical properties of the measured signals. Conditions…

Systems and Control · Electrical Eng. & Systems 2021-10-28 Shengling Shi , Xiaodong Cheng , Paul M. J. Van den Hof

Stochastic chemical processes are described by the chemical master equation satisfying the law of mass-action. We first ask whether the dual master equation, which has the same steady state as the chemical master equation, but with inverted…

The functions of many networked systems in physics, biology or engineering rely on a coordinated or synchronized dynamics of its constituents. In power grids for example, all generators must synchronize and run at the same frequency and…

Adaptation and Self-Organizing Systems · Physics 2017-09-13 Debsankha Manik , Marc Timme , Dirk Witthaut

We study the effect of intrinsic noise on the thermodynamic balance of complex chemical networks subtending cellular metabolism and gene regulation. A topological network property called deficiency, known to determine the possibility of…

Molecular Networks · Quantitative Biology 2015-11-12 Matteo Polettini , Artur Wachtel , Massimiliano Esposito

Stochastic reaction networks are mathematical models with a wide range of applications in biochemistry, ecology, and epidemiology, and are often complex to analyze. Except for some special cases, it is generally difficult to predict how the…

Probability · Mathematics 2026-04-02 Daniele Cappelletti , Giulio Cuniberti , Paola Siri

We consider a deep structured linear network under sparsity constraints. We study sharp conditions guaranteeing the stability of the optimal parameters defining the network. More precisely, we provide sharp conditions on the network…

Optimization and Control · Mathematics 2023-02-03 Francois Malgouyres

Many real-world networks such as social networks consist of strategic agents. The topology of these networks often plays a crucial role in determining the ease and speed with which certain information driven tasks can be accomplished.…

Social and Information Networks · Computer Science 2017-07-03 Swapnil Dhamal , Y. Narahari

The aim of this paper is to prove results about the existence and stability of multiple steady states in a system of ordinary differential equations introduced by R. Lev Bar-Or to model the interactions between T cells and macrophages.…

Cell Behavior · Quantitative Biology 2011-07-28 Alan D. Rendall

Previous work on sensitivity analysis in Bayesian networks has focused on single parameters, where the goal is to understand the sensitivity of queries to single parameter changes, and to identify single parameter changes that would enforce…

Artificial Intelligence · Computer Science 2012-07-19 Hei Chan , Adnan Darwiche

The fundamental decomposition of a chemical reaction network (CRN) is induced by partitioning the reaction set into "fundamental classes". It was the basis of the Higher Deficiency Algorithm for mass action systems of Ji and Feinberg, and…

Dynamical Systems · Mathematics 2020-08-13 Bryan S. Hernandez

Multistationarity is the property of a system to exhibit two distinct equilibria (steady-states) under otherwise identical conditions, and it is a phenomenon of recognized importance for biochemical systems. Multistationarity may appear in…

Dynamical Systems · Mathematics 2022-05-26 Nicola Vassena

Stochastic reaction networks are mathematical models frequently used in, but not limited to, biochemistry. These models are continuous-time Markov chains whose transition rates depend on certain parameters called rate constants, which…

Probability · Mathematics 2025-08-14 Daniele Cappelletti , Aidan Howells , Chuang Xu

In this work and the supporting Parts II [2] and III [3], we provide a rather detailed analysis of the stability and performance of asynchronous strategies for solving distributed optimization and adaptation problems over networks. We…

Systems and Control · Computer Science 2014-12-17 Xiaochuan Zhao , Ali H. Sayed

Consider a Markovian Petri net with race policy. The marking process has a "product form" stationary distribution if the probability of viewing a given marking can be decomposed as the product over places of terms depending only on the…

Discrete Mathematics · Computer Science 2010-06-01 Jean Mairesse , Hoang-Thach Nguyen

State estimation plays a key role in the transition from the passive to the active operation of distribution systems, as it allows to monitor these networks and, successively, to perform control actions. However, designing state estimators…

Systems and Control · Electrical Eng. & Systems 2020-11-25 Marta Vanin , Tom Van Acker , Reinhilde D'hulst , Dirk Van Hertem

Scaling transformations involving a small parameter ({\em degenerate scalings}) are frequently used for ordinary differential equations that model (bio-) chemical reaction networks. They are motivated by quasi-steady state (QSS) of certain…

Dynamical Systems · Mathematics 2022-09-20 Christian Lax , Sebastian Walcher

Underpinning the past decades of work on the design, initialization, and optimization of neural networks is a seemingly innocuous assumption: that the network is trained on a \textit{stationary} data distribution. In settings where this…

Machine Learning · Computer Science 2024-03-01 Clare Lyle , Zeyu Zheng , Khimya Khetarpal , Hado van Hasselt , Razvan Pascanu , James Martens , Will Dabney