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The cellular phenotype is described by a complex network of molecular interactions. Elucidating network properties that distinguish disease from the healthy cellular state is therefore of critical importance for gaining systems-level…

Molecular Networks · Quantitative Biology 2012-11-22 James West , Ginestra Bianconi , Simone Severini , Andrew Teschendorff

One important question in neuroscience is how global behavior in a brain network emerges from the interplay between network connectivity and the neural dynamics of individual nodes. To better understand this theoretical relationship, we…

Neurons and Cognition · Quantitative Biology 2022-09-13 Anca Radulescu , Johan Nakuci , Simone Evans , Sarah Muldoon

The availability of new data sources on human mobility is opening new avenues for investigating the interplay of social networks, human mobility and dynamical processes such as epidemic spreading. Here we analyze data on the time-resolved…

In recent years, applications of data mining methods are become more popular in many fields of medical diagnosis and evaluations. The data mining methods are appropriate tools for discovering and extracting of available knowledge in medical…

Computational Engineering, Finance, and Science · Computer Science 2013-12-10 Peyman Mohammadi , Abdolreza Hatamlou , Mohammad Masdari

We use the annealed formulation of complex networks to study the dynamical behavior of disease spreading on both static and adaptive networked systems. This unifying approach relies on the annealed adjacency matrix, representing one network…

Physics and Society · Physics 2010-11-09 Beniamino Guerra , Jesus Gomez-Gardenes

Structural changes in a network representation of a system (e.g.,different experimental conditions, time evolution), can provide insight on its organization, function and on how it responds to external perturbations. The deeper…

Data Analysis, Statistics and Probability · Physics 2021-01-04 Leonardo L. Portes , Michael Small

Most infectious diseases spread on a dynamic network of human interactions. Recent studies of social dynamics have provided evidence that spreading patterns may depend strongly on detailed micro-dynamics of the social system. We have…

Physics and Society · Physics 2015-09-23 Arkadiusz Stopczynski , Alex Sandy Pentland , Sune Lehmann

Objective: We investigate whether deep learning techniques for natural language processing (NLP) can be used efficiently for patient phenotyping. Patient phenotyping is a classification task for determining whether a patient has a medical…

Multi-scale biomedical knowledge networks are expanding with emerging experimental technologies that generates multi-scale biomedical big data. Link prediction is increasingly used especially in bipartite biomedical networks to identify…

Social and Information Networks · Computer Science 2022-02-25 Jinjiang Guo , Jie Li , Dawei Leng , Lurong Pan

Modern disease classification often overlooks molecular commonalities hidden beneath divergent clinical presentations. This study introduces a transcriptomics-driven framework for discovering disease relationships by analyzing over 1300…

Genomics · Quantitative Biology 2025-08-08 Ke Chen , Haohan Wang

The study of neuronal morphology is important not only for its potential relationship with neuronal dynamics, but also as a means to classify diverse types of cells and compare than among species, organs, and conditions. In the present…

Neurons and Cognition · Quantitative Biology 2024-03-11 Alexandre Benatti , Henrique F. de Arruda , Luciano da F. Costa

Cells with the same genome can exist in different phenotypes. and can change between distinct phenotypes when subject to specific stimuli and microenvironments. Some examples include cell differentiation during development, reprogramming…

Quantitative Methods · Quantitative Biology 2022-09-28 Jianhua Xing

Network science has become an essential interdisciplinary tool for understanding complex biological systems. However, because these systems undergo continuous, often stimulus-driven changes in both structure and function, traditional static…

Molecular Networks · Quantitative Biology 2025-05-19 Abir Khazaal , Fatemeh Vafaee

Empirical studies of graphs have contributed enormously to our understanding of complex systems. Known today as network science, what was originally a theoretical study of graphs has grown into a more scientific exploration of communities…

Quantitative Methods · Quantitative Biology 2020-01-01 Ryan E. Langendorf , Debra S. Goldberg

Recent advances of information technology in biomedical sciences and other applied areas have created numerous large diverse data sets with a high dimensional feature space, which provide us a tremendous amount of information and new…

Applications · Statistics 2008-12-18 Yulan Liang , Arpad Kelemen

In the field of health-care and bio-medical research, understanding the relationship between the symptoms of diseases is crucial for early diagnosis and determining hidden relationships between diseases. The study aimed to understand the…

Artificial Intelligence · Computer Science 2023-02-24 Zolzaya Dashdorj , Stanislav Grigorev , Munguntsatsral Dovdondash

Networks built to model real world phenomena are characeterised by some properties that have attracted the attention of the scientific community: (i) they are organised according to community structure and (ii) their structure evolves with…

Social and Information Networks · Computer Science 2019-09-04 Giulio Rossetti , Rémy Cazabet

Traditional mathematical models of epidemic disease had for decades conventionally considered static structure for contacts. Recently, an upsurge of theoretical inquiry has strived towards rendering the models more realistic by…

Physics and Society · Physics 2016-01-20 Babak Fotouhi , Mehrdad Khani Shirkoohi

With the increasing availability and size of multi-omics datasets, investigating the casual relationships between molecular phenotypes has become an important aspect of exploring underlying biology and genetics. This paper aims to introduce…

Molecular Networks · Quantitative Biology 2022-01-31 Jack Kelly , Carlo Berzuini , Bernard Keavney , Maciej Tomaszewski , Hui Guo

Graphs are essential representations of many real-world data such as social networks. Recent years have witnessed the increasing efforts made to extend the neural network models to graph-structured data. These methods, which are usually…

Machine Learning · Computer Science 2018-11-07 Yao Ma , Ziyi Guo , Zhaochun Ren , Eric Zhao , Jiliang Tang , Dawei Yin
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