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In this letter we study the full semi-conservative treatment of a model for the co-evolution of a virus and an adaptive immune system. Regions of viability are calculated for both conservatively and semi-conservatively replicating viruses…

Populations and Evolution · Quantitative Biology 2009-11-10 Yisroel Brumer , Eugene I. Shakhnovich

For robots to handle the numerous factors that can affect them in the real world, they must adapt to changes and unexpected events. Evolutionary robotics tries to solve some of these issues by automatically optimizing a robot for a specific…

Robotics · Computer Science 2018-05-10 Tønnes F. Nygaard , Charles P. Martin , Eivind Samuelsen , Jim Torresen , Kyrre Glette

In large populations, multiple beneficial mutations may be simultaneously spreading. In asexual populations, these mutations must either arise on the same background or compete against each other. In sexual populations, recombination can…

Populations and Evolution · Quantitative Biology 2013-12-19 D. B. Weissman , O. Hallatschek

Mutation is one of the most important stages of the genetic algorithm because of its impact on the exploration of global optima, and to overcome premature convergence. There are many types of mutation, and the problem lies in selection of…

In this paper we analyse the genetic evolution of a diploid hermaphroditic population, which is modelled by a three-type nonlinear birth-and-death process with competition and Mendelian reproduction. In a recent paper, Collet et al., 2013…

Probability · Mathematics 2017-08-28 Anton Bovier , Rebecca Neukirch

If two species exhibit different nonlinear responses to a single shared resource, and if each species modifies the resource dynamics such that this favors its competitor, they may stably coexist. This coexistence mechanism, known as…

Populations and Evolution · Quantitative Biology 2015-06-16 Florian Hartig , Tamara Münkemüller , Karin Johst , Ulf Dieckmann

Growing efforts to measure fitness landscapes in molecular and microbial systems are premised on a tight relationship between landscape topography and evolutionary trajectories. This relationship, however, is far from being straightforward:…

Populations and Evolution · Quantitative Biology 2019-12-13 Matteo Smerlak

We propose a minimal off-lattice model of living organisms where just a very few dynamical rules of growth are assumed. The stable coexistence of many clusters is detected when we replace the global restriction rule by a locally applied…

Physics and Society · Physics 2021-08-19 B. F. de Oliveira , M. V. de Moraes , D. Bazeia , A. Szolnoki

To approximate convolutions which occur in evolution equations with memory terms, a variable-stepsize algorithm is presented for which advancing N steps requires only O(N log(N)) operations and O(log(N)) active memory, in place of O(N^2)…

Numerical Analysis · Mathematics 2007-05-23 María López-Fernández , Christian Lubich , Achim Schädle

We study a parabolic Lotka-Volterra type equation that describes the evolution of a population structured by a phenotypic trait, under the effects of mutations and competition for resources modelled by a nonlocal feedback. The limit of…

Analysis of PDEs · Mathematics 2020-03-13 Manon Costa , Christèle Etchegaray , Sepideh Mirrahimi

A population genetics model based on a multitype branching process, or equivalently a Galton-Watson branching process for multiple alleles, is pre- sented. The diffusion limit forward Kolmogorov equation is derived for the case of neutral…

Populations and Evolution · Quantitative Biology 2018-02-21 Conrad J. Burden , Yi Wei

The general Markov plus invariable sites (GM+I) model of biological sequence evolution is a two-class model in which an unknown proportion of sites are not allowed to change, while the remainder undergo substitutions according to a Markov…

Populations and Evolution · Quantitative Biology 2011-11-10 Elizabeth S. Allman , John A. Rhodes

This paper deals with the ergodicity and the existence of a strong law of large numbers for adaptive Markov Chain Monte Carlo. We show that a diminishing adaptation assumption together with a drift condition for positive recurrence is…

Probability · Mathematics 2013-03-05 Yves Atchadé , Gersende Fort

The presence of phenomena analogous to phase transition in Statistical Mechanics, has been suggested in the evolution of a polygenic trait under stabilizing selection, mutation and genetic drift. By using numerical simulations of a model…

Populations and Evolution · Quantitative Biology 2017-02-13 Annalisa Fierro , Sergio Cocozza , Antonella Monticelli , Giovanni Scala , Gennaro Miele

A procedure is described for estimating evolutionary rate matrices from observed site frequency data. The procedure assumes (1) that the data are obtained from a constant size population evolving according to a stationary Wright-Fisher…

Populations and Evolution · Quantitative Biology 2016-07-18 Conrad J. Burden , Yurong Tang

We find that the hypothesis made by Jan, Stauffer and Moseley [Theory in Biosc., 119, 166 (2000)] for the evolution of sex, namely a strategy devised to escape extinction due to too many deleterious mutations, is sufficient but not…

Soft Condensed Matter · Physics 2009-11-07 Erkan Tuzel , Volkan Sevim , Ayse Erzan

In this paper, we consider an individual-based model with power law mutation probability. In this setting, we use the large population limit with a subsequent ``small mutations'' limit to derive the canonical equation of adaptive dynamics.…

Populations and Evolution · Quantitative Biology 2024-02-14 Tobias Paul

We propose and analyze a self-adaptive version of the $(1,\lambda)$ evolutionary algorithm in which the current mutation rate is part of the individual and thus also subject to mutation. A rigorous runtime analysis on the OneMax benchmark…

Neural and Evolutionary Computing · Computer Science 2018-12-03 Benjamin Doerr , Carsten Witt , Jing Yang

Biological evolution depends on the passing down to subsequent generations of genetic information encoding beneficial traits, and on the removal of unfit individuals by a selection mechanism. However, selection acts on phenotypes, and is…

Populations and Evolution · Quantitative Biology 2026-05-01 Bastien Mallein , Francesco Paparella , Emmanuel Schertzer , Zsófia Talyigás

We consider a mutation-selection model of a population structured by the spatial variables and a trait variable which is the diffusion rate. Competition for resource is local in spatial variables, but nonlocal in the trait variable. We…

Analysis of PDEs · Mathematics 2020-04-20 King-Yeung Lam , Yuan Lou
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