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We study the unzipping of double stranded DNA (dsDNA) by applying a pulling force at a fraction $s$ $(0 \le s \le 1)$ from the anchored end. From exact analytical and numerical results, the complete phase diagram is presented. The phase…

Soft Condensed Matter · Physics 2009-11-10 Rajeev Kapri , Somendra M. Bhattacharjee , Flavio Seno

Single molecule experiments on single- and double stranded DNA have sparked a renewed interest in the force-extension of polymers. The extensible Freely Jointed Chain (FJC) model is frequently invoked to explain the observed behavior of…

Biological Physics · Physics 2009-11-07 Cornelis Storm , Philip Nelson

Calculations for two electrons in an elliptic quantum dot, using symmetry breaking at the unrestricted Hartree-Fock level and subsequent restoration of the broken parity via projection techniques, show that the electrons can localize and…

Mesoscale and Nanoscale Physics · Physics 2007-05-23 Constantine Yannouleas , Uzi Landman

The proton structure function is re-deduced from the data of deep inelastic electron-proton scattering after enhanced correction that is made due to the multiple scattering effect. The Glauber approach is used to account for the multiple…

High Energy Physics - Phenomenology · Physics 2007-05-23 N. M. Hassan , W. R. El-Harby , R. W. El-Moualed And M. T. Hussein

The first level of folding of DNA in eukaryotes is provided by the so called '10 nm chromatin fibre', where DNA wraps around histone proteins (approx. 10 nm in size) to form nucleosomes, which go on to create a zig zagging bead on a string…

Biological Physics · Physics 2016-03-23 S. Tesoro , I. Ali , A. N. Morozov , N. Sulaiman , D. Marenduzzo

The formation of bubbles in nucleic acids (NAs) are fundamental in many biological processes such as DNA replication, recombination, telomeres formation, nucleotide excision repair, as well as RNA transcription and splicing. These precesses…

Biomolecules · Quantitative Biology 2007-05-23 D. Hennig , J. F. R. Archilla , J. M. Romero

The computational modelling of DNA is becoming crucial in light of new advances in DNA nanotechnology, single-molecule experiments and in vivo DNA tampering. Here we present a mesoscopic model for double stranded DNA (dsDNA) at the single…

Soft Condensed Matter · Physics 2025-02-03 Y. A. G. Fosado , D. Michieletto , J. Allan , C. Brackley , O. Henrich , D. Marenduzzo

We theoretically determine the probability distribution function of the net field of the random planar structure of dipoles which represent polarized particles. At small surface concentrations c of the point dipoles this distribution is…

Statistical Mechanics · Physics 2012-05-04 Andrey V. Panov

Tensors are ubiquitous in science and engineering and tensor factorization approaches have become important tools for the characterization of higher order structure. Factorizations includes the outer-product rank Canonical Polyadic…

Machine Learning · Statistics 2023-10-05 Jesper Løve Hinrich , Morten Mørup

Within a simple elastic theory, we study the elongation versus force characteristics of a supercoiled DNA molecule at thermal equilibrium in the regime of small supercoiling. The partition function is mapped to the path integral…

Soft Condensed Matter · Physics 2016-08-31 C. Bouchiat , M. Mezard

DNA is an attractive candidate for data storage. Its millennial durability and nanometer scale offer exceptional data density and longevity. Its relevance to medical applications also drives advances in DNA-related biotechnology. To protect…

Information Theory · Computer Science 2025-11-25 Yu-Ting Lin , Hsin-Po Wang , Venkatesan Guruswami

We study the role of cations on the stability of double stranded DNA (dsDNA) molecules.It is known that the two strands of double stranded DNA(dsDNA) have negative charge due to phosphate group. Cations in the form of salt in the solution,…

Soft Condensed Matter · Physics 2015-09-29 Amar Singh , Navin Singh

Partition functions of N=2 theories on the squashed 3-sphere have been recently shown to localise to matrix integrals. By explicitly evaluating the matrix integral we show that abelian partition functions can be expressed as a sum of…

High Energy Physics - Theory · Physics 2015-06-03 Sara Pasquetti

We investigate the translocation of a single stranded DNA (ssDNA) through a pore, which fluctuates between two conformations, by using coupled master equations (ME). The probability density function (PDF) of the first passage times (FPT) of…

Subcellular Processes · Quantitative Biology 2007-05-23 O. Flomenbom , J. Klafter

We investigate the statistical properties of a randomly branched 3--functional $N$--link polymer chain without excluded volume, whose one point is fixed at the distance $d$ from the impenetrable surface in a 3--dimensional space. Exactly…

Statistical Mechanics · Physics 2009-11-10 M. V. Tamm , S. K. Nechaev , I. Ya. Erukhimovich

Purpose: To present a closed formalism calculating charged particle radiation damage induced in DNA. The formalism is valid for all types of charged particles and due to its closed nature is suited to provide fast conversion of dose to…

Medical Physics · Physics 2016-04-13 Frank Van den Heuvel

We report a novel simulation strategy that enables us to identify key parameters controlling the experimentally measurable characteristics of structural protein tags on dsDNA construct translocating through a double nanopore setup. First,…

Soft Condensed Matter · Physics 2022-02-14 Swarnadeep Seth , Arthur Rand , Walter Reisner , William B. Dunbar , Robert Sladek , Aniket Bhattacharya

A detailed description of the conformational plasticity of double stranded DNA (ds) is a necessary framework for understanding protein-DNA interactions. Until now, however structure and kinetics of the transition from the basic conformation…

Soft Condensed Matter · Physics 2011-03-04 Pasquale Bianco , Lorenzo Bongini , Luca Melli , Mario Dolfi , Vincenzo Lombardi

We compute the partition functions of $\mathcal{N} = 1$ gauge theories on $S^2 \times \mathbb{R}^2_\varepsilon$ using supersymmetric localization. The path integral reduces to a sum over vortices at the poles of $S^2$ and at the origin of…

High Energy Physics - Theory · Physics 2021-07-02 Taro Kimura , Jun Nian , Peng Zhao

We consider two complementary polymer strands of length $L$ attached by a common end monomer. The two strands bind through complementary monomers and at low temperatures form a double stranded conformation (zipping), while at high…

Statistical Mechanics · Physics 2015-03-19 Jean-Charles Walter , Alessandro Ferrantini , Enrico Carlon , Carlo Vanderzande