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The question of testing for equality in distribution between two linear models, each consisting of sums of distinct discrete independent random variables with unequal numbers of observations, has emerged from the biological research. In…

Statistics Theory · Mathematics 2020-09-01 Giulio Prevedello , Ken R. Duffy

New automated and high-throughput methods allow the manipulation and selection of numerous bacterial populations. In this manuscript we are interested in the neutral diversity patterns that emerge from such a setup in which many bacterial…

Populations and Evolution · Quantitative Biology 2024-03-13 Guilhem Doulcier , Amaury Lambert

We review recent work on the statistical mechanics of Von Neumann's growth model and discuss its application to cellular metabolic networks. In this context, we present a detailed analysis of the physiological scenario underlying optimality…

Disordered Systems and Neural Networks · Physics 2015-06-05 Andrea De Martino , Enzo Marinari , Andrea Romualdi

In this article, a new mathematical model of human population growth as an autonomous non-Markov queuing system with an unlimited number of servers and two types of applications is proposed. The research of this system was carried out a…

Probability · Mathematics 2020-05-22 Mariia Nosova

We use a model whose rules were inspired by population genetics, the random capability growth model, to describe the statistical details observed in experiments of fragmentation of brittle platelike objects, and in particular the existence…

Statistical Mechanics · Physics 2016-12-21 M. A. F. Gomes , Viviane M. de Oliveira

This is work in progress. We make it accessible hoping that people might find the idea useful. We propose a discrete, recursive 5-compartment model for the spread of epidemics, which we call {\em SEPIR-model}. Under mild assumptions which…

Populations and Evolution · Quantitative Biology 2020-09-02 Matthias Kreck , Erhard Scholz

We develop a stochastic framework for viral population dynamics at the cellular level that explicitly incorporates the replication cycle with random stage durations. The model is formulated as a structured birth-death process coupled with a…

Populations and Evolution · Quantitative Biology 2026-05-13 Seong Jun Park

Small sample sizes in clinical studies arises from factors such as reduced costs, limited subject availability, and the rarity of studied conditions. This creates challenges for accurately calculating confidence intervals (CIs) using the…

Methodology · Statistics 2025-11-11 Mulan Wu , Mengyu Xu , Dongyun Kim

In this paper, the statistical properties of Newton s method algorithm output in a specific case have been studied. The relative frequency density of this sample converges to a well-defined function, prompting us to explore its…

Data Analysis, Statistics and Probability · Physics 2024-07-16 Taki Kirouani

We present in this article an analysis of some of the properties of the density field realized in numerical simulations for power-law initial power-spectra in the case of a critical density universe. We compare our numerical results in the…

Astrophysics · Physics 2009-10-31 P. Valageas , C. Lacey , R. Schaeffer

Replication through cell division is one of the most fundamental processes of life and a major driver of dynamics in systems ranging from bacterial colonies to embryogenesis, tissues and tumors. While regulation often plays a role in…

Soft Condensed Matter · Physics 2024-10-21 Lukas Hupe , Yoav G. Pollack , Jonas Isensee , Aboutaleb Amiri , Ramin Golestanian , Philip Bittihn

We consider an age-size structured cell population model based on the cell cycle length. The model is described by a first order partial differential equation with initial-boundary conditions. Using the theory of semigroups of positive…

Analysis of PDEs · Mathematics 2022-06-15 Katarzyna Pichór , Ryszard Rudnicki

We model the growth of a cell population using a piecewise deterministic Markov branching tree. In this model, each cell splits into two offspring at a division rate $B(x)$, which depends on its size $x$. The size of each cell increases…

Probability · Mathematics 2024-09-06 Nathalie Krell

In human microbiome studies, sequencing reads data are often summarized as counts of bacterial taxa at various taxonomic levels specified by a taxonomic tree. This paper considers the problem of analyzing two repeated measurements of…

Applications · Statistics 2017-02-17 Pixu Shi , Hongzhe Li

The Min system in Escherichia coli directs division to the centre of the cell through pole-to-pole oscillations of the MinCDE proteins. We present a one dimensional stochastic model of these oscillations which incorporates membrane…

Subcellular Processes · Quantitative Biology 2007-05-23 Filipe Tostevin , Martin Howard

The Luria-Delbr\"uck distribution is a classical model of mutations in cell kinetics. It is obtained as a limit when the probability of mutation tends to zero and the number of divisions to infinity. It can be interpreted as a compound…

Applications · Statistics 2013-09-11 Agnès Hamon , Bernard Ycart

This paper is concerned with the evolution of haploid organisms that reproduce asexually. In a seminal piece of work, Eigen and coauthors proposed the quasispecies model in an attempt to understand such an evolutionary process. Their work…

Populations and Evolution · Quantitative Biology 2012-03-07 Narendra M. Dixit , Piyush Srivastava , Nisheeth K. Vishnoi

Mathematical and computational models can assist in gaining an understanding of cell behavior at many levels of organization. Here, we review models in the literature that focus on eukaryotic cell motility at 3 size scales: intracellular…

Cell Behavior · Quantitative Biology 2021-01-27 Andreas Buttenschön , Leah Edelstein-Keshet

We propose a model for evolution aiming to reproduce statistical features of fossil data, in particular the distributions of extinction events, the distribution of species per genus and the distribution of lifetimes, all of which are known…

Populations and Evolution · Quantitative Biology 2008-06-06 Peter Klimek , Stefan Thurner , Rudolf Hanel

Preterm birth is associated with premature cervical remodeling, yet current clinical assessments cannot detect the underlying microstructural changes in collagen organization. We apply imaging Mueller polarimetry to murine cervical tissue…