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Since the seminal work of Powell, the relationships between the population growth rate, the probability distributions of generation time, and the distribution of cell age have been known for the bacterial population in a steady state of…

Biological Physics · Physics 2023-06-02 Jakub Jędrak , Marcin Rubin , Anna Ochab-Marcinek

In most biological studies and processes, cell proliferation and population dynamics play an essential role. Due to this ubiquity, a multitude of mathematical models has been developed to describe these processes. While the simplest models…

Populations and Evolution · Quantitative Biology 2012-02-23 J. Hasenauer , D. Schittler , F. Allgower

Protein distributions measured under a broad set of conditions in bacteria and yeast were shown to exhibit a common skewed shape, with variances depending quadratically on means. For bacteria these properties were reproduced by temporal…

Biological Physics · Physics 2015-10-28 Naama Brenner , C. M. Newman , Dino Osmanovic , Yitzhak Rabin , Hanna Salman , D. L. Stein

We generalize the SiZer of Chaudhuri and Marron (J. Amer. Statist. Assoc. 94 (1999) 807-823, Ann. Statist. 28 (2000) 408-428) for the detection of shape parameters of densities on the real line to the case of circular data. It turns out…

Spatial models where growth is limited to the edge of the expansions have been instrumental to understand the population dynamics and the clone size distribution in growing cellular populations, such as microbial colonies and avascular…

Populations and Evolution · Quantitative Biology 2022-06-08 Armin Eghdami , Jayson Paulose , Diana Fusco

Recent experiments have supported the Adder model for E. coli division control. This model posits that bacteria grow, on average, a fixed size before division. It also predicts decorrelation between the noise in the added size and the size…

Stem cell regeneration is a crucial biological process for most self-renewing tissues during the development and maintenance of tissue homeostasis. In developing the mathematical models of stem cell regeneration and tissue development, cell…

Quantitative Methods · Quantitative Biology 2024-01-17 Jinzhi Lei

Within the framework of hierarchical clustering we show that a simple Press-Schechter-like approximation, based on spherical dynamics, provides a good estimate of the evolution of the density field in the quasi-linear regime up to $\Sigma…

Astrophysics · Physics 2007-05-23 P. Valageas

Using demographic data of high spatial resolution for a region in the south of Europe, we study the population over fixed-size spatial cells. We find that, counterintuitively, the distribution of the number of inhabitants per cell increases…

Physics and Society · Physics 2022-12-07 Alvaro Corral , Montserrat García del Muro

Reconstructing past population size from present day genetic data is a major goal of population genetics. Recent empirical studies infer population size history using coalescent-based models applied to a small number of individuals. Here we…

Populations and Evolution · Quantitative Biology 2014-09-30 Junhyong Kim , Elchanan Mossel , Miklós Z. Rácz , Nathan Ross

For various species of biological cells, experimental observations indicate the existence of universal distributions of the cellular size, scaling relations between the cell-size moments and simple rules for the cell-size control. We…

Soft Condensed Matter · Physics 2017-01-12 David A. Kessler , Stanislav Burov

The multivariate hypergeometric distribution describes sampling without replacement from a discrete population of elements divided into multiple categories. Addressing a gap in the literature, we tackle the challenge of estimating discrete…

Machine Learning · Computer Science 2024-06-11 Liam Hodgson , Danilo Bzdok

Using a population dynamics inspired by an ensemble of growing cells, a set of fluctuation theorems linking observables measured at the lineage and population levels are derived. One of these relations implies specific inequalities…

Populations and Evolution · Quantitative Biology 2021-11-08 Reinaldo García-García , Arthur Genthon , David Lacoste

The paper describes a new class of capture-recapture models for closed populations when individual covariates are available. The novelty consists in combining a latent class model for the distribution of the capture history, where the class…

Methodology · Statistics 2021-11-08 Antonio Forcina , Francesco Bartolucci

The Giardin\`a-Kurchan-Peliti algorithm is a numerical procedure that uses population dynamics in order to calculate large deviation functions associated to the distribution of time-averaged observables. To study the numerical errors of…

Statistical Mechanics · Physics 2017-05-11 Takahiro Nemoto , Esteban Guevara Hidalgo , Vivien Lecomte

Many complex ecosystems, such as those formed by multiple microbial taxa, involve intricate interactions amongst various sub-communities. The most basic relationships are frequently modeled as co-occurrence networks in which the nodes…

Machine Learning · Statistics 2017-03-09 Diego Hernán Díaz Martínez , Christine H. Lee , Peter T. Kim , Washington Mio

Accurate estimates of the reproduction ratio are crucial to project infectious disease epidemic evolution and guide public health response. Here, we prove that estimates of the reproduction ratio based on inference from surveillance data…

Physics and Society · Physics 2025-01-08 Piero Birello , Michele Re Fiorentin , Boxuan Wang , Vittoria Colizza , Eugenio Valdano

Despite recent molecular technique improvements, biological knowledge remains incomplete. Reasoning on living systems hence implies to integrate heterogeneous and partial informations. Although current investigations successfully focus on…

Quantitative Methods · Quantitative Biology 2009-09-29 Jérémie Bourdon , Damien Eveillard , Samuel Gabillard , Theo Merle

Structured populations are ubiquitous across the biological sciences. Mathematical models of these populations allow us to understand how individual physiological traits drive the overall dynamics in aggregate. For example, linear age- or…

Analysis of PDEs · Mathematics 2022-04-25 Sabina L. Altus , Jeffrey C. Cameron , David M. Bortz

We study time continuous branching processes with exponentially distributed lifetimes, with two types of cells that proliferate according to binary fission. A range of possible system dynamics are considered, each of which is characterized…

Probability · Mathematics 2022-04-27 Nam H Nguyen , Marek Kimmel
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