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Related papers: GPU-based ultra fast IMRT plan optimization

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A challenge in high-dimensional inverse problems is developing iterative solvers to find the accurate solution of regularized optimization problems with low computational cost. An important example is computed tomography (CT) where both…

Numerical Analysis · Mathematics 2024-12-16 Alessandro Perelli , Carola-Bibiane Schonlieb , Matthias J. Ehrhardt

Intensity Modulated Radiation Therapy is an effective cancer treatment. Models based on the Generalized Equivalent Uniform Dose (gEUD) provide radiation plans with excellent planning target volume coverage and low radiation for organs at…

We present a new algorithm to quickly generate high-performance GPU implementations of complex imaging and vision pipelines, directly from high-level Halide algorithm code. It is fully automatic, requiring no schedule templates or…

Programming Languages · Computer Science 2023-08-29 Luke Anderson , Andrew Adams , Karima Ma , Tzu-Mao Li , Tian Jin , Jonathan Ragan-Kelley

Implicit neural representations (INRs) provide a parameter-efficient and fully differentiable image model for CT reconstruction. However, optimizing INRs for CT reconstruction using standard auto-differentiation techniques can be…

Image and Video Processing · Electrical Eng. & Systems 2026-04-14 Mahrokh Najaf , Gregory Ongie

Searching for sources of electromagnetic emission in spectral-line radio astronomy interferometric data is a computationally intensive process. Parallel programming techniques and High Performance Computing hardware may be used to improve…

Instrumentation and Methods for Astrophysics · Physics 2015-07-20 Stefan Westerlund , Christopher Harris

Intensity-modulated proton therapy (IMPT) offers superior dose conformity with reduced exposure to surrounding healthy tissues compared to conventional photon therapy. Improving IMPT delivery efficiency reduces motion-related uncertainties,…

Medical Physics · Physics 2025-04-15 Ya-Nan Zhu , Nimita Shinde , Bowen Lin , Hao Gao

Proton therapy is a modality in fast development. Characterized by a maximum dose deposition at the end of the proton trajectory followed by a sharp fall-off, proton beams can deliver a highly conformal dose to the tumor while sparing…

Medical Physics · Physics 2022-05-18 François Smekens , Nicolas Freud , Bruno Sixou , Guillaume Beslon , Jean M Létang

VMAT optimization is a computationally challenging problem due to its large data size, high degrees of freedom, and many hardware constraints. High-performance graphics processing units have been used to speed up the computations. However,…

Medical Physics · Physics 2017-02-08 Zhen Tian , Fei Peng , Michael Folkerts , Jun Tan , Xun Jia , Steve B. Jiang

We present the methodology of a photon-conserving, spatially-adaptive, ray-tracing radiative transfer algorithm, designed to run on multiple parallel Graphic Processing Units (GPUs). Each GPU has thousands computing cores, making them…

Cosmology and Nongalactic Astrophysics · Physics 2018-10-17 Blake Hartley , Massimo Ricotti

In many applied optimization settings, parameters that define the constraints may not guarantee the best possible solution, and superior solutions might exist that are infeasible for the given parameter values. Removing such constraints,…

Optimization and Control · Mathematics 2024-07-22 Farzin Ahmadi , Todd R. McNutt , Kimia Ghobadi

Conventional planning objectives in optimization of intensity-modulated radiotherapy treatment (IMRT) plans are designed to minimize the violation of dose-volume histogram (DVH) thresholds using penalty functions. Although successful in…

Medical Physics · Physics 2023-07-19 Lovisa Engberg , Kjell Eriksson , Anders Forsgren , Björn Hårdemark

We present an improved inverse ray-shooting code based on GPUs for generating microlensing magnification maps. In addition to introducing GPUs for acceleration, we put the efforts in two aspects: (i) A standard circular lens plane is…

Instrumentation and Methods for Astrophysics · Physics 2022-06-08 Wenwen Zheng , Xuechun Chen , Guoliang Li , Hou-zun Chen

In the treatment plan optimization for intensity modulated radiation therapy (IMRT), dose-deposition coefficient (DDC) matrix is often pre-computed to parameterize the dose contribution to each voxel in the volume of interest from each…

Medical Physics · Physics 2013-03-15 Zhen Tian , Masoud Zarepisheh , Xun Jia , Steve B. Jiang

Adaptive mesh refinement (AMR) reduces computational costs in CFD by concentrating resolution where needed, but efficiently embedding complex, non-aligned geometries on GPUs remains challenging. We present a GPU-native algorithm for…

Computational Engineering, Finance, and Science · Computer Science 2026-04-28 Khodr Jaber , Ebenezer E. Essel , Pierre E. Sullivan

Tomographic image sizes keep increasing over time and while the GPUs that compute the tomographic reconstruction are also increasing in memory size, they are not doing so fast enough to reconstruct the largest datasets. This problem is…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-05-10 Ander Biguri , Reuben Lindroos , Robert Bryll , Hossein Towsyfyan , Hans Deyhle , Richard Boardman , Mark Mavrogordato , Manjit Dosanjh , Steven Hancock , Thomas Blumensath

Temporally modulated pulsed radiotherapy (TMPRT) delivers conventional fraction doses of radiation using temporally separated pulses of low doses (<30 cGy) yielding fraction-effective dose rates of around 6.7 cGy/min with the goal to…

Medical Physics · Physics 2026-01-13 Christian Velten , Adam Bayliss , Jiayi Huang , Wolfgang A. Tomé

Four-dimensional computed tomography (4DCT) has been widely used in cancer radiotherapy for accurate target delineation and motion measurement for tumors in thorax and upper abdomen areas. However, 4DCT simulation is associated with much…

Medical Physics · Physics 2015-05-19 Zhen Tian , Xun Jia , Steve B. Jiang

This work details a highly efficient implementation of the 3D scale-invariant feature transform (SIFT) algorithm, for the purpose of machine learning from large sets of volumetric medical image data. The primary operations of the 3D SIFT…

Computer Vision and Pattern Recognition · Computer Science 2021-12-21 Jean-Baptiste Carluer , Laurent Chauvin , Jie Luo , William M. Wells , Ines Machado , Rola Harmouche , Matthew Toews

Purpose: To enhance an in-house graphic-processing-unit (GPU) accelerated virtual particle (VP)-based Monte Carlo (MC) proton dose engine (VPMC) to model aperture blocks in both dose calculation and optimization for pencil beam scanning…

Heterogeneity in the cell population of cancer tissues poses many challenges in cancer diagnosis and treatment. Studying the heterogeneity in cell populations from gene expression measurement data in the context of cancer research is a…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-01-31 Anik Chaudhuri , Anwoy Mohanty , Manoranjan Satpathy