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Optimizing the performance of computational fluid dynamics (CFD) applications accelerated by graphics processing units (GPUs) is crucial for efficient simulations. In this study, we employed a machine learning-based autotuning technique to…

Performance · Computer Science 2024-02-21 Weicheng Xue , Christohper John Roy

We present a novel application of Tensor Network methods in cancer treatment as a potential tool to solve the dose optimization problem in radiotherapy. In particular, the Intensity-Modulated Radiation Therapy (IMRT) technique - that allows…

Medical Physics · Physics 2021-08-11 Samuele Cavinato , Timo Felser , Marco Fusella , Marta Paiusco , Simone Montangero

We developed a novel method of creating intensity modulated proton arc therapy (IMPAT) plans that uses computing resources efficiently and may offer a dosimetric benefit for patients with ependymoma or similar tumor geometries. Our IMPAT…

Statistical iterative reconstruction is expected to improve the image quality of megavoltage computed tomography (MVCT). However, one of the challenges of iterative reconstruction is its large computational cost. The purpose of this work is…

In this work, we propose FFDP, a set of IO-aware non-GEMM fused kernels supplemented with a distributed framework for image registration at unprecedented scales. Image registration is an inverse problem fundamental to biomedical and life…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Rohit Jena , Vedant Zope , Pratik Chaudhari , James C. Gee

This paper presents a heterogeneous adaptive mesh refinement (AMR) framework for efficient simulation of moderately stiff reactive problems. This framework features an elaborate subcycling-in-time algorithm along with a specialized…

Computational Physics · Physics 2025-06-04 Yuqi Wang , Yadong Zeng , Ralf Deiterding , Jianhan Liang

Multimodal foundation models are transformative in sequential recommender systems, leveraging powerful representation learning capabilities. While Parameter-efficient Fine-tuning (PEFT) is commonly used to adapt foundation models for…

Information Retrieval · Computer Science 2024-07-23 Junchen Fu , Xuri Ge , Xin Xin , Alexandros Karatzoglou , Ioannis Arapakis , Jie Wang , Joemon M. Jose

Molecular similarity search has been widely used in drug discovery to identify structurally similar compounds from large molecular databases rapidly. With the increasing size of chemical libraries, there is growing interest in the efficient…

Hardware Architecture · Computer Science 2021-09-15 Hongwu Peng , Shiyang Chen , Zhepeng Wang , Junhuan Yang , Scott A. Weitze , Tong Geng , Ang Li , Jinbo Bi , Minghu Song , Weiwen Jiang , Hang Liu , Caiwen Ding

Purpose: The FLASH effect, which reduces the radiosensitivity of healthy tissue while maintaining tumor control at high dose rates, has shown potential for improving radiation therapy. Conformal FLASH proton therapy involves advanced…

Medical Physics · Physics 2023-04-13 Sylvain Deffet , Edmond Sterpin

We introduce the first end-to-end learning-based solution to near-field Photometric Stereo (PS), where the light sources are close to the object of interest. This setup is especially useful for reconstructing large immobile objects. Our…

Computer Vision and Pattern Recognition · Computer Science 2022-03-31 Daniel Lichy , Soumyadip Sengupta , David W. Jacobs

We describe a GPU-enabled approach for real-time optical frequency comb spectroscopy in which data is recorded, Fourier transformed, normalized, and fit at data rates up to 2.2 GB/s. As an initial demonstration we have applied this approach…

Instrumentation and Detectors · Physics 2023-07-26 Sean M. Bresler , David A. Long , Benjamin J. Reschovsky , Yiliang. Bao , Thomas W. LeBrun

The incoherent scatter radar (ISR) technique is a powerful remote sensing tool for ionosphere and thermosphere dynamics in the near-Earth space environment. Weak ISR scatter from naturally occurring Langmuir oscillations, or plasma lines,…

Data Analysis, Statistics and Probability · Physics 2023-12-01 Natalie Hilliard , Juha Vierinen , Philip J. Erickson

We conduct a theoretical study of various solution methods for the adaptive fractionation problem. The two messages of this paper are: (i) dynamic programming (DP) is a useful framework for adaptive radiation therapy, particularly adaptive…

Medical Physics · Physics 2012-02-16 Jagdish Ramakrishnan , David Craft , Thomas Bortfeld , John N. Tsitsiklis

Detailed analysis of efficiency and pollutant emission characteristics of practical turbulent combustion devices using complex combustion kinetics often depend on the interactions between the combustion chemistry involving both gasses…

Computational Physics · Physics 2020-05-26 Sudip Adhikari , Alan Sayre , Abhilash J Chandy

Purpose: Prior AI-based dose prediction studies in photon and proton therapy often neglect underlying physics, limiting their generalizability to handle outlier clinical cases, especially for pencil beam scanning proton therapy (PBSPT). Our…

We propose to develop deep learning models that can predict Pareto optimal dose distributions by using any given set of beam angles, along with patient anatomy, as input to train the deep neural networks. We implement and compare two deep…

Medical Physics · Physics 2021-01-27 Gyanendra Bohara , Azar Sadeghnejad Barkousaraie , Steve Jiang , Dan Nguyen

Cardiac action potential models allow examination of a variety of cardiac dynamics, including how behavior may change under specific interventions. To study a specific scenario, including patient-specific cases, model parameter sets must be…

Computational Engineering, Finance, and Science · Computer Science 2025-04-21 Darby I. Cairns , Maxfield R. Comstock , Flavio H. Fenton , Elizabeth M. Cherry

We present a set of rules to guide the design of GPU algorithms. These rules are grounded on the principle of reducing waste in GPU utility to achieve good speed up. In accordance to these rules, we propose GPU algorithms for 2D…

Graphics · Computer Science 2020-07-02 Zhenghai Chen , Tiow-Seng Tan , Hong-Yang Ong

The high computational cost of ab-initio methods limits their application in predicting electronic properties at the device scale. Therefore, an efficient method is needed to map the atomic structure to the electronic structure quickly.…

Materials Science · Physics 2025-09-09 Yunlong Wang , Zhixin Liang , Chi Ding , Junjie Wang , Zheyong Fan , Hui-Tian Wang , Dingyu Xing , Jian Sun

Proton computed tomography (pCT) is a novel medical imaging modality for mapping the distribution of proton relative stopping power (RSP) in medical objects of interest. Compared to conventional X-ray computed tomography, where range…