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A key overall goal of biomolecular simulations is the characterization of "mechanism" -- the pathways through configuration space of processes such as conformational transitions and binding. Some amount of heterogeneity is intrinsic to the…

Chemical Physics · Physics 2018-10-25 Ernesto Suárez , Daniel M. Zuckerman

Systems of particles interacting with "stealthy" pair potentials have been shown to possess infinitely degenerate disordered hyperuniform classical ground states with novel physical properties. Previous attempts to sample the infinitely…

Statistical Mechanics · Physics 2015-08-20 Ge Zhang , Frank H. Stillinger , Salvatore Torquato

Assessing the convergence of a biomolecular simulation is an essential part of any computational investigation. This is because many important quantities (e.g., free energy differences) depend on the relative populations of different…

Biological Physics · Physics 2009-11-11 Edward Lyman , Daniel M. Zuckerman

We introduce a variational method for the approximation of ground states of strongly interacting spin systems in arbitrary geometries and spatial dimensions. The approach is based on weighted graph states and superpositions thereof. These…

Quantum Physics · Physics 2007-05-23 S. Anders , M. B. Plenio , W. Dür , F. Verstraete , H. -J. Briegel

Many robotic systems are underactuated, meaning not all degrees of freedom can be directly controlled due to lack of actuators, input constraints, or state-dependent actuation. This property, compounded by modeling uncertainties and…

Systems and Control · Electrical Eng. & Systems 2025-10-10 Daniel M. Cherenson , Dimitra Panagou

In recent years, network embedding methods have garnered increasing attention because of their effectiveness in various information retrieval tasks. The goal is to learn low-dimensional representations of vertexes in an information network…

Social and Information Networks · Computer Science 2017-11-02 Chih-Ming Chen , Yi-Hsuan Yang , Yian Chen , Ming-Feng Tsai

Fitting mixed models to complex survey data is a challenging problem. Most methods in the literature, including the most widely used one, require a close relationship between the model structure and the survey design. In this paper we…

Methodology · Statistics 2023-11-23 Thomas Lumley , Xudong Huang

A network as a substrate for dynamic processes may have its own dynamics. We propose a model for networks which evolve together with diffusing particles through a coupled dynamics, and investigate emerging structural property. The model…

Statistical Mechanics · Physics 2009-11-10 Sang-Woo Kim , Jae Dong Noh

Sampling the collective, dynamical fluctuations that lead to nonequilibrium pattern formation requires probing rare regions of trajectory space. Recent approaches to this problem based on importance sampling, cloning, and spectral…

Statistical Mechanics · Physics 2022-02-14 Jiawei Yan , Hugo Touchette , Grant M. Rotskoff

We introduce a unified formulation of variational methods for simulating ground state properties of quantum many-body systems. The key feature is a novel variational method over quantum circuits via infinitesimal unitary transformations,…

Quantum Physics · Physics 2009-11-13 Christopher M. Dawson , Jens Eisert , Tobias J. Osborne

Probabilistic graphical models (PGMs) are widely used to discover latent structure in data, but their success hinges on selecting an appropriate model design. In practice, model specification is difficult and often requires iterative…

Machine Learning · Computer Science 2026-04-08 Kevin Zhang , Yixin Wang

This study presents a finite element analysis approach to non-linear and linearized tensegrity dynamics based on the Lagrangian method with nodal coordinate vectors as the generalized coordinates. In this paper, nonlinear tensegrity…

Applied Physics · Physics 2021-06-07 Shuo Ma , Muhao Chen , Robert E. Skelton

The weighting of critical-point samples in the weighted randomized maximum likelihood method depend on the magnitude of the data mismatch at the critical points and on the Jacobian of the transformation from the prior density to the…

Methodology · Statistics 2023-01-16 Yuming Ba , Dean S. Oliver

Natural and social multivariate systems are commonly studied through sets of simultaneous and time-spaced measurements of the observables that drive their dynamics, i.e., through sets of time series. Typically, this is done via hypothesis…

Statistical Finance · Quantitative Finance 2020-07-01 Riccardo Marcaccioli , Giacomo Livan

It is increasingly common to encounter prediction tasks in the biomedical sciences for which multiple datasets are available for model training. Common approaches such as pooling datasets and applying standard statistical learning methods…

Machine Learning · Statistics 2021-10-05 Gabriel Loewinger , Rolando Acosta Nunez , Rahul Mazumder , Giovanni Parmigiani

We present a general model for the growth of weighted networks in which the structural growth is coupled with the edges' weight dynamical evolution. The model is based on a simple weight-driven dynamics and a weights' reinforcement…

Statistical Mechanics · Physics 2009-11-10 Alain Barrat , Marc Barthelemy , Alessandro Vespignani

We propose a hybrid meta-learning framework for forecasting and anomaly detection in nonlinear dynamical systems characterized by nonstationary and stochastic behavior. The approach integrates a physics-inspired simulator that captures…

Machine Learning · Computer Science 2025-06-18 Abdullah Burkan Bereketoglu

Many dynamical systems, including thermal, fluid, and multi-agent systems, can be represented as weighted graphs. In this paper we consider whether the unstable states of such systems can be observed from limited discrete-time measurement,…

Systems and Control · Electrical Eng. & Systems 2022-09-28 Uduak Inyang-Udoh , Michael Shanks , Neera Jain

Dynamic substructuring (DS) methods encompass a range of techniques to decompose large structural systems into multiple coupled subsystems. This decomposition has the principle benefit of reducing computational time for dynamic simulation…

Computational Engineering, Finance, and Science · Computer Science 2020-07-01 Thomas Simpson , Dimitrios Giagopoulos , Vasilis Dertimanis , Eleni Chatzi

We analyst in detail a new approach to the monitoring and forecasting of the onset of transitions in high dimensional complex systems (see Phys. Rev. Lett . vol. 113, 264102 (2014)) by application to the Tangled Nature Model of evolutionary…

Adaptation and Self-Organizing Systems · Physics 2015-08-03 Duccio Piovani , Jelena Grujic , Henrik Jeldtoft Jensen