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In clinical trials, inferences on clinical outcomes are often made conditional on specific selective processes. For instance, only when a treatment demonstrates a significant effect on the primary outcome, further analysis is conducted to…

Methodology · Statistics 2025-04-15 Tianyu Pan , Vivek Charu , Ying Lu , Lu Tian

This paper explores the challenges of constructing suitable inferential models in scenarios where the parameter of interest is determined in light of the data, such as regression after variable selection. Two compelling arguments for…

Statistics Theory · Mathematics 2025-07-22 Daniel Garcia Rasines , G. Alastair Young

Statistical inference after model selection requires an inference framework that takes the selection into account in order to be valid. Following recent work on selective inference, we derive analytical expressions for inference after…

Methodology · Statistics 2017-09-26 David Rügamer , Sonja Greven

In this article, we review selective inference, a set of techniques for inference when the statistical question asked is a function of the data. This setting often arises in contemporary scientific workflows, where hypotheses and parameters…

Methodology · Statistics 2026-04-14 Anna Neufeld , Ronan Perry , Daniela Witten

Variable selection for regression models plays a key role in the analysis of biomedical data. However, inference after selection is not covered by classical statistical frequentist theory which assumes a fixed set of covariates in the…

Methodology · Statistics 2021-07-21 Michael Kammer , Daniela Dunkler , Stefan Michiels , Georg Heinze

The inferential model (IM) framework provides valid prior-free probabilistic inference by focusing on predicting unobserved auxiliary variables. But, efficient IM-based inference can be challenging when the auxiliary variable is of higher…

Statistics Theory · Mathematics 2015-01-20 Ryan Martin , Chuanhai Liu

We investigate generically applicable and intuitively appealing prediction intervals based on $k$-fold cross validation. We focus on the conditional coverage probability of the proposed intervals, given the observations in the training…

Statistics Theory · Mathematics 2022-05-13 Lukas Steinberger , Hannes Leeb

Conditional probabilities are a core concept in machine learning. For example, optimal prediction of a label $Y$ given an input $X$ corresponds to maximizing the conditional probability of $Y$ given $X$. A common approach to inference tasks…

Machine Learning · Computer Science 2017-08-09 Yoav Wald , Amir Globerson

We develop a general approach to valid inference after model selection. At the core of our framework is a result that characterizes the distribution of a post-selection estimator conditioned on the selection event. We specialize the…

Statistics Theory · Mathematics 2016-05-04 Jason D. Lee , Dennis L. Sun , Yuekai Sun , Jonathan E. Taylor

Investigators often use the data to generate interesting hypotheses and then perform inference for the generated hypotheses. P-values and confidence intervals must account for this explorative data analysis. A fruitful method for doing so…

Methodology · Statistics 2018-02-06 Keli Liu , Jelena Markovic , Robert Tibshirani

This work addresses the problem of conducting valid inference for additive and linear mixed models after model selection. One possible solution to overcome overconfident inference results after model selection is selective inference, which…

Methodology · Statistics 2020-12-22 David Rügamer , Philipp F. M. Baumann , Sonja Greven

We consider an empirical likelihood framework for inference for a statistical model based on an informative sampling design. Covariate information is incorporated both through the weights and the estimating equations. The estimator is based…

Methodology · Statistics 2019-05-03 Sanjay Chaudhuri , Mark S. Handcock

Selective inference (post-selection inference) is a methodology that has attracted much attention in recent years in the fields of statistics and machine learning. Naive inference based on data that are also used for model selection tends…

Methodology · Statistics 2021-11-25 Yoshiyuki Ninomiya , Yuta Umezu , Ichiro Takeuchi

We consider the problem of inference for parameters selected to report only after some algorithm, the canonical example being inference for model parameters after a model selection procedure. The conditional correction for selection…

Methodology · Statistics 2019-01-30 Jelena Markovic , Jonathan Taylor , Jeremy Taylor

Conformal predictors are machine learning algorithms that output prediction sets that have a guarantee of marginal validity for finite samples with minimal distributional assumptions. This is a property that makes conformal predictors…

Machine Learning · Computer Science 2021-03-03 Anthony Bellotti

Parameters of sub-populations can be more relevant than super-population ones. For example, a healthcare provider may be interested in the effect of a treatment plan for a specific subset of their patients; policymakers may be concerned…

Methodology · Statistics 2023-03-22 Ying Jin , Dominik Rothenhäusler

Valid inference after model selection is currently a very active area of research. The polyhedral method, pioneered by Lee, et al. (2016), allows for valid inference after model selection if the model selection event can be described by…

Statistics Theory · Mathematics 2019-07-08 Danijel Kivaranovic , Hannes Leeb

Intelligent test requires efficient and effective analysis of high-dimensional data in a large scale. Traditionally, the analysis is often conducted by human experts, but it is not scalable in the era of big data. To tackle this challenge,…

Machine Learning · Computer Science 2022-07-04 Yiwen Liao , Tianjie Ge , Raphaël Latty , Bin Yang

We consider the problem of estimating the conditional distribution of a post-model-selection estimator where the conditioning is on the selected model. The notion of a post-model-selection estimator here refers to the combined procedure…

Statistics Theory · Mathematics 2007-11-06 Hannes Leeb , Benedikt M. Pötscher

We examine the conditions under which descriptive inference can be based directly on the observed distribution in a non-probability sample, under both the super-population and quasi-randomisation modelling approaches. Review of existing…

Statistics Theory · Mathematics 2018-10-02 Li-Chun Zhang
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