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Related papers: Intramolecular fluorescence correlation spectrosco…

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Correlative microscopy is a powerful technique that combines the advantages of multiple imaging modalities to achieve a comprehensive understanding of investigated samples. For example, fluorescence microscopy provides unique functional…

We consider a two-level atom stimulated by a coherent monochromatic laser and we study how to enhance the squeezing of the fluorescence light and of the atom itself in the presence of a Wiseman-Milburn feedback mechanism, based on the…

Quantum Physics · Physics 2009-01-21 A. Barchielli , M. Gregoratti , M. Licciardo

Protein rotational kinetics are essential for understanding macromolecular behavior in crowded environments, yet measuring these dynamics at solid-liquid interfaces remains a significant challenge due to low signal strengths. Here, we…

The currently existing theory of fluorescence correlation spectroscopy(FCS) is based on the linear fluctuation theory originally developed by Einstein, Onsager, Lax, and others as a phenomenological approach to equilibrium fluctuations in…

Biological Physics · Physics 2015-04-01 Mauricio J. Del Razo , Wenxiao Pan , Hong Qian , Guang Lin

A ubiquitous observation in crowded cell membranes is that molecular transport does not follow Fickian diffusion but exhibits subdiffusion. The microscopic origin of such a behaviour is not understood and highly debated. Here we discuss the…

Soft Condensed Matter · Physics 2011-02-15 Felix Höfling , Karl-Ulrich Bamberg , Thomas Franosch

Inferring functional relationships within complex networks from static snapshots of a subset of variables is a ubiquitous problem in science. For example, a key challenge of systems biology is to translate cellular heterogeneity data…

Molecular Networks · Quantitative Biology 2024-08-09 Euan Joly-Smith , Zitong Jerry Wang , Andreas Hilfinger

Cells measure concentrations of external ligands by capturing ligand molecules with cell surface receptors. The numbers of molecules captured by different receptors co-vary because they depend on the same extrinsic ligand fluctuations.…

Neurons and Cognition · Quantitative Biology 2016-09-21 Vijay Singh , Martin Tchernookov , Ilya Nemenman

Versatile, ultracompact, easy-to-handle, high-sensitivity sensors are compelling tools for in situ pivotal applications, such as medical diagnostics, security and safety assessments, and environmental control. In this work, we combine…

Conformational dynamics of biomolecules are of fundamental importance for their function. Single-molecule F\"orster Resonance Energy Transfer (smFRET) is a powerful approach to inform on the structure and the dynamics of labeled molecules.…

Speckle-correlation imaging techniques are widely used for non-invasive imaging through complex scattering media. While light propagation through multimode fibers and scattering media share many analogies, reconstructing images through…

We investigate how short and long electron trajectory contributions to high harmonic emission and their interferences give access to intra-molecular dynamics. In the case of unaligned molecules, we show experimental evidences that the long…

DNA is subject to large deformations in a wide range of biological processes. Two key examples illustrate how such deformations influence the readout of the genetic information: the sequestering of eukaryotic genes by nucleosomes, and DNA…

Biomolecules · Quantitative Biology 2015-11-10 Stephanie Johnson , Martin Lindén , Rob Phillips

Tracking cells in time-lapse videos is an essential technique for monitoring cell population dynamics at a single-cell level. Current methods for cell tracking are developed on videos with mostly single, constant signals and do not detect…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Florian Bürger , Martim Dias Gomes , Nica Gutu , Adrián E. Granada , Noémie Moreau , Katarzyna Bozek

In biological cells and novel diagnostic devices biochemical receptors need to be sensitive to extremely small concentration changes of signaling molecules. The accuracy of such molecular signaling is ultimately limited by the counting…

Subcellular Processes · Quantitative Biology 2023-04-06 Aljaz Godec , Ralf Metzler

Fluorescence spectroscopy is an image correlation technique to analyze and characterize the molecular dynamics from a sequence of fluorescence images. Many image correlation techniques have been developed for different applications [1]. But…

Quantitative Methods · Quantitative Biology 2017-10-24 C. Chen , P. Paul-Gilloteaux , T. Vignaud , J. Salamero , F. Waharte

The full understanding of cellular functions requires information about protein numbers for various biomolecular assemblies and their dynamics, which can be partly accessed by super-resolution fluorescence microscopy. Yet, many protein…

Biological Physics · Physics 2020-06-17 Kristin S. Grußmayer , Klaus Yserentant , Dirk-Peter Herten

The development of spectroscopic techniques able to detect and verify quantum coherence is a goal of increasing importance given the rapid progress of new quantum technologies, the advances in the field of quantum thermodynamics, and the…

Quantum Physics · Physics 2020-05-27 Carlos Sánchez Muñoz , Frank Schlawin

Variable-length feedback codes can provide advantages over fixed-length feedback or non-feedback codes. This letter focuses on uncoded variable-symbol-length feedback communication and analyzes the autocorrelation and spectrum of the…

Information Theory · Computer Science 2022-11-23 Chin-Wei Hsu , Hun-Seok Kim , Achilleas Anastasopoulos

The influence of decoherence and bonding on the linear conductance of single double-stranded DNA molecules is examined by fitting a phenomenological statistical model developed recently (EPJB {\bf 68}, 237 (2009)) to experimental results.…

Soft Condensed Matter · Physics 2010-09-30 M. Zilly , O. Ujsaghy , D. E. Wolf

DNA-interacting proteins have roles multiple processes, many operating as molecular machines which undergo dynamic metastable transitions to bring about their biological function. To fully understand this molecular heterogeneity, DNA and…

Biomolecules · Quantitative Biology 2015-04-15 Adam J. M. Wollman , Helen Miller , Zhaokun Zhou , Mark C. Leake