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Related papers: LinkedCT: A Linked Data Space for Clinical Trials

200 papers

As clinical decision-making increasingly moves toward individualized and context-specific treatment recommendations, reliance on any single evidence source, randomized or observational, may be insufficient. Principled integration of…

The surging amount of biomedical literature & digital clinical records presents a growing need for text mining techniques that can not only identify but also semantically relate entities in unstructured data. In this paper we propose a text…

Computation and Language · Computer Science 2021-12-28 Hasham Ul Haq , Veysel Kocaman , David Talby

Structured data offers a sophisticated mechanism for the organization of information. Existing methodologies for the text-serialization of structured data in the context of large language models fail to adequately address the heterogeneity…

Computation and Language · Computer Science 2024-02-20 YiQiu Guo , Yuchen Yang , Ya Zhang , Yu Wang , Yanfeng Wang

The Semantic Publishing Challenge series aims at investigating novel approaches for improving scholarly publishing using Linked Data technology. In 2014 we had bootstrapped this effort with a focus on extracting information from…

Digital Libraries · Computer Science 2015-08-26 Angelo Di Iorio , Christoph Lange , Anastasia Dimou , Sahar Vahdati

In this paper we analyse the functional requirements of linked data citation and identify a minimal set of operations and primitives needed to realize such task. Citing linked data implies solving a series of data provenance issues and…

Digital Libraries · Computer Science 2019-07-12 Dario De Nart , Dante Degl'Innocenti , Marco Peressotti

Clinical coding is a critical task in healthcare, although traditional methods for automating clinical coding may not provide sufficient explicit evidence for coders in production environments. This evidence is crucial, as medical coders…

Computation and Language · Computer Science 2025-04-08 Leonor Barreiros , Isabel Coutinho , Gonçalo M. Correia , Bruno Martins

Despite great advances in the area of Semantic Web, industry rather seldom adopts Semantic Web technologies and their storage and query concepts. Instead, relational databases (RDB) are often deployed to store business-critical data, which…

Databases · Computer Science 2021-08-02 Markus Schröder , Michael Schulze , Christian Jilek , Andreas Dengel

High-quality datasets are typically required for accomplishing data-driven tasks, such as training medical diagnosis models, predicting real-time traffic conditions, or conducting experiments to validate research hypotheses. Consequently,…

Information Retrieval · Computer Science 2025-09-03 Pengyue Li , Sheng Wang , Hua Dai , Zhiyu Chen , Zhifeng Bao , Brian D. Davison

There is a growing need to semantically process and integrate clinical data from different sources for Clinical Data Management and Clinical Decision Support in the healthcare IT industry. In the clinical practice domain, the semantic gap…

Databases · Computer Science 2012-10-25 Hong Sun , Kristof Depraetere , Jos De Roo , Boris De Vloed , Giovanni Mels , Dirk Colaert

Linked Open Data (LOD) is the publicly available RDF data in the Web. Each LOD entity is identfied by a URI and accessible via HTTP. LOD encodes globalscale knowledge potentially available to any human as well as artificial intelligence…

Clinical trials are critical for advancing medical treatments but remain prohibitively expensive and time-consuming. Accurate prediction of clinical trial outcomes can significantly reduce research and development costs and accelerate drug…

Machine Learning · Computer Science 2025-06-06 Fengze Liu , Haoyu Wang , Joonhyuk Cho , Dan Roth , Andrew W. Lo

Automatic extraction of clinical concepts is an essential step for turning the unstructured data within a clinical note into structured and actionable information. In this work, we propose a clinical concept extraction model for automatic…

Computation and Language · Computer Science 2018-11-28 Henghui Zhu , Ioannis Ch. Paschalidis , Amir Tahmasebi

The Semantic Web began to emerge as its standards and technologies developed rapidly in the recent years. The continuing development of Semantic Web technologies has facilitated publishing explicit semantics with data on the Web in RDF data…

Artificial Intelligence · Computer Science 2017-07-13 Serkan Ayvaz , Mehmet Aydar

The integration of real-world data (RWD) and randomized controlled trials (RCT) is increasingly important for advancing causal inference in scientific research. This combination holds great promise for enhancing the efficiency of causal…

Methodology · Statistics 2024-07-02 Xi Lin , Jens Magelund Tarp , Robin J. Evans

Data Linkage is an important step that can provide valuable insights for evidence-based decision making, especially for crucial events. Performing sensible queries across heterogeneous databases containing millions of records is a complex…

Databases · Computer Science 2015-10-09 Mohammed Gollapalli

Randomized controlled trials (RCTs) have been the cornerstone of clinical evidence; however, their cost, duration, and restrictive eligibility criteria limit power and external validity. Studies using real-world data (RWD), historically…

Methodology · Statistics 2025-11-26 Shu Yang , Margaret Gamalo , Haoda Fu

This article presents a novel approach to estimate semantic entity similarity using entity features available as Linked Data. The key idea is to exploit ranked lists of features, extracted from Linked Data sources, as a representation of…

Over the years several studies have demonstrated the ability to identify potential drug-drug interactions via data mining from the literature (MEDLINE), electronic health records, public databases (Drugbank), etc. While each one of these…

Computers and Society · Computer Science 2015-07-21 Juan M. Banda , Tobias Kuhn , Nigam H. Shah , Michel Dumontier

With the generation of personal and medical data at several locations, medical data science faces unique challenges when working on distributed datasets. Growing data protection requirements in recent years drastically limit the use of…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-09-13 Maximilian Jugl , Sascha Welten , Yongli Mou , Yeliz Ucer Yediel , Oya Deniz Beyan , Ulrich Sax , Toralf Kirsten

Digital collaboration systems support asynchronous work over replicated data, where conflicts arise when concurrent operations cannot be unambiguously integrated into a shared history. While Conflict-Free Replicated Data Types (CRDTs)…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-14 Georgii Semenov , Vitaly Aksenov